Find Business Hotels in Charleston, MO
Change your mindBook hotels with free cancellation
Be pickySearch almost a million properties worldwide
Check availability on Charleston Business Hotels
Tonight
Aug 10 - Aug 11Tomorrow
Aug 11 - Aug 12This weekend
Aug 14 - Aug 16Next weekend
Aug 21 - Aug 23Our top choices for Charleston business-friendly hotels
NT$2,142
NT$2,377 total
includes taxes & fees
Sep 10 - Sep 11
NT$3,576
NT$4,111 total
includes taxes & fees
Aug 16 - Aug 17
3. Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67)
Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67)Sikeston
Sharika West
NT$2,271
NT$2,589 total
includes taxes & fees
Aug 13 - Aug 14
4. Holiday Inn Express & Suites Sikeston Southwest by IHG
Holiday Inn Express & Suites Sikeston Southwest by IHGSikeston
michael
NT$3,133
NT$3,548 total
includes taxes & fees
Aug 23 - Aug 24
NT$2,081
NT$2,372 total
includes taxes & fees
Sep 10 - Sep 11
6. Fairfield Inn & Suites by Marriott Sikeston
Fairfield Inn & Suites by Marriott SikestonSikeston
Dwain
NT$3,544
NT$4,013 total
includes taxes & fees
Sep 3 - Sep 4
NT$3,067
NT$3,496 total
includes taxes & fees
Sep 10 - Sep 11
NT$3,521
NT$3,987 total
includes taxes & fees
Aug 23 - Aug 24
View all properties
Top Charleston Hotel Reviews
Drury Inn & Suites Sikeston, MO
10/10 Excellent
"Great stay!"
The Riverstone Hotel Charleston-Sikeston
8/10 Good
"The ad and picture for the hotel is a little deceiving. It shows a large fountain in front of the front lobby. There was none. This is the former Quality Inn Hotel was not good at all. The hotel has been cleaned up and rebranded. The room was nice. My only concern was all the bugs that were outside the room door and flew into the room when you opened your door at night. The other thing that I did not like was the surprise $100 fee that I had to pay up front for potential damage to the room. This fee was returned during check out."
Candlewood Suites Cape Girardeau by IHG
10/10 Excellent
"Our stove had a short in it so I wasn’t able to cook"
Super 8 by Wyndham Charleston/Sikeston East MO
10/10 Excellent
"Nice staff. Very accommodating."
Drury Plaza Hotel Cape Girardeau Conference Center
10/10 Excellent
"Everything about this property is 1000000/100000"
Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG
10/10 Excellent
"Very nice hotel and staff. Would definitely recommend "
Best Western Plus Sikeston I-55
10/10 Excellent
"Front desk was super helpful"
Drury Inn & Suites Cape Girardeau
10/10 Excellent
"Everything was awesome, highly recommended this hotel"
Hampton Inn Cape Girardeau I 55 East
10/10 Excellent
"Good Job!"
Frequently asked questions
Explore a world of travel with Expedia
- Hotels near Cape Girardeau Conservation Nature Center
- Cape Girardeau Hotels
- Hotels with an Indoor Pool in Sikeston
- Pet-Friendly Hotels in Dexter
- Pet-Friendly Hotels in Sikeston
- Bloomfield Hotels
- Charleston Hotels
- Pet-Friendly Hotels in Charleston
- Cheap Hotels in Charleston
- Luxury Hotels in Sikeston
- Hotels with an Indoor Pool in Jackson
- Apartments in Lilbourn
- Apartments in Mississippi County
- Hotels near Cape Splash Family Aquatic Center
- Gay friendly Hotels in Miner
- Motels in Bernie
- Bertrand Hotels
- Cheap Hotels in Sikeston
- 5 Star Hotels in Bertrand
- Malden Hotels
- Hotels near Malden Regional
- Hotels with smoking rooms in Sikeston
- Hotels with Bars in Hayti
- Marble Hill Hotels
- Resorts & Hotels with Spas in Hayti
- Apartments in Scott County
- 3 Star Hotels in Oran
- Hotels near Sikeston Memorial Municipal
- Casino Hotels in Hayti
- New Madrid Hotels
- Marston Hotels
- Hotels with Bars in Jackson
- Flights from Stuart (SUA) to Cape Girardeau (CGI)
- Flights from Bernie
- Flights from Chicago (CHI) to Cape Girardeau (CGI)
- Flights from Los Angeles (LAX) to Cape Girardeau (CGI)
- Flights from Meridian (MEI) to Cape Girardeau (CGI)
- Flights from Shanghai (PVG) to Cape Girardeau (CGI)
- Flights from Indianapolis (IND) to Cape Girardeau (CGI)
- Flights from Hartford (BDL) to Cape Girardeau (CGI)
- Flights from Indiana (IDI) to Cape Girardeau (CGI)
- Flights from Fresno (FAT) to Cape Girardeau (CGI)
- Flights from Hilton Head Island (HHH) to Cape Girardeau (CGI)
- Flights from Oakland (OAK) to Cape Girardeau (CGI)
- Flights from Boston (BOS) to Malden (MAW)
- Flights from Andrews (ADR) to Cape Girardeau (CGI)
- Flights from Orlando (SFB) to Cape Girardeau (CGI)
- Flights from Dhaka (DAC) to Cape Girardeau (CGI)
- Flights from Santa Barbara (SBA) to Cape Girardeau (CGI)
- Flights from Lawton (LAW) to Cape Girardeau (CGI)
- Flights from Rhinelander (RHI) to Cape Girardeau (CGI)
- Flights to Charleston
- Flights from Tupelo (TUP) to Cape Girardeau (CGI)
- Flights from Kingaroy (KGY) to Cape Girardeau (CGI)
- Flights from Montgomery (MGM) to Cape Girardeau (CGI)
- Flights from Boise (BOI) to Cape Girardeau (CGI)
- Flights from Corozal (CZH) to Cape Girardeau (CGI)
- Flights from Gambell (GAM) to Cape Girardeau (CGI)
- Flights from Harare (HRE) to Cape Girardeau (CGI)
- Flights from Marsa Matruh (MUH) to Cape Girardeau (CGI)
- Flights from Escanaba (ESC) to Cape Girardeau (CGI)
- Flights from Fayetteville (XNA) to Cape Girardeau (CGI)
- Flights from Joplin (JLN) to Cape Girardeau (CGI)
- Flights from Ilhéus Airport (IOS) to Cape Girardeau (CGI)
- Flights from Corvallis (CVO) to Cape Girardeau (CGI)
- Flights from Elmira (ELM) to Cape Girardeau (CGI)
- Flights from Lafayette (LFT) to Cape Girardeau (CGI)
- Flights from Malden Regional
- Flights from Hays (HYS) to Cape Girardeau (CGI)
- Flights from Billings (BIL) to Cape Girardeau (CGI)
- Flights from Perth (PER) to Cape Girardeau (CGI)
- Flights from Fort Smith (FSM) to Cape Girardeau (CGI)
- Flights from Gulfport (GPT) to Cape Girardeau (CGI)
- Flights from Cheyenne (CYS) to Cape Girardeau (CGI)
- Flights from Mexico City (MEX) to Cape Girardeau (CGI)
- Flights from South Bend (SBN) to Sikeston (SIK)
- Enterprise Rental Cars in Lambert
- Fox Rental Cars Rental Cars in Cape Girardeau Municipal
- Budget Rental Cars in Oran
- Car rental Jackson
- Alamo Rent A Car Rental Cars in Malden Regional
- Enterprise Rental Cars in Benton
- Dollar Rent A Car Rental Cars in Pocahontas
- Enterprise Rental Cars in Cape Girardeau Municipal
- Car rentals near Lazy L Safari Park
- Car rental Dexter
- Enterprise Rental Cars in Miner