Find Family Hotels in Central West End, MO

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Check availability on Central West End Family Hotels

Tonight
Dec 28 - Dec 29
Tomorrow
Dec 29 - Dec 30
Next weekend
Jan 2 - Jan 4
In two weeks
Jan 9 - Jan 11

Our top choices for Central West End family-friendly hotels

Lobby
AC Hotel St. Louis Central West End

AC Hotel St. Louis Central West End

AC Hotel St. Louis Central West End
4.0 star property
Central West End
9.0 out of 10, Wonderful, (686)
"Clean room, Helpful staff, Easy/cheap parking "
United States
Delaney
The price is NT$3,866
NT$4,560 total
includes taxes & fees
Jan 2 - 2026/1/3
AC Hotel St. Louis Central West End
Terrace/patio
The West End

The West End

The West End
2.0 star property
Central West End
8.4 out of 10, Very Good, (410)
"Great stay!"
United States
Shaniqua
The price is NT$2,196
NT$3,164 total
includes taxes & fees
Jan 6 - 2026/1/7
The West End
Property amenity
Aloft St. Louis Cortex

Aloft St. Louis Cortex

Aloft St. Louis Cortex
3.0 star property
Central West End
8.6 out of 10, Excellent, (836)
"Great Stay "
United States
Brandon Russell
The price is NT$3,649
NT$4,267 total
includes taxes & fees
Dec 30 - Dec 31
Aloft St. Louis Cortex
Restaurant
Hotel Indigo St Louis - Central West End by IHG

Hotel Indigo St Louis - Central West End by IHG

Hotel Indigo St Louis - Central West End by IHG
3.5 star property
Central West End
8.2 out of 10, Very Good, (1000)
"Very friendly staff. Clean modern hotel room with comfortable bed and spacious shower! "
United States
Courtney
The price is NT$3,646
NT$4,645 total
includes taxes & fees
Jan 26 - 2026/1/27
Hotel Indigo St Louis - Central West End by IHG
Bar (on property)
Magnolia Hotel St. Louis, a Tribute Portfolio Hotel

Magnolia Hotel St. Louis, a Tribute Portfolio Hotel

Magnolia Hotel St. Louis, a Tribute Portfolio Hotel
4.0 star property
Downtown St. Louis
8.8 out of 10, Excellent, (1170)
"Staff was helpful at suggesting places to eat and shop"
United States
Ann Marie
The price is NT$3,049
NT$3,626 total
includes taxes & fees
Jan 25 - 2026/1/26
Magnolia Hotel St. Louis, a Tribute Portfolio Hotel
Lobby
Drury Inn & Suites Southwest St. Louis

Drury Inn & Suites Southwest St. Louis

Drury Inn & Suites Southwest St. Louis
3.0 star property
Valley Park
9.4 out of 10, Exceptional, (1001)
"Clean room, breakfast, and friendly staff"
United States
Angie
The price is NT$3,615
NT$4,229 total
includes taxes & fees
Jan 4 - 2026/1/5
Drury Inn & Suites Southwest St. Louis
Exterior
Hampton Inn St. Charles St. Peters

Hampton Inn St. Charles St. Peters

Hampton Inn St. Charles St. Peters
2.5 star property
St. Charles
8.0 out of 10, Very Good, (1009)
"very friendly staff and good location "
United States
Heather
The price is NT$2,810
NT$3,229 total
includes taxes & fees
Jan 4 - 2026/1/5
Hampton Inn St. Charles St. Peters
Rooftop terrace
Drury Plaza Hotel St. Louis at the Arch

Drury Plaza Hotel St. Louis at the Arch

Drury Plaza Hotel St. Louis at the Arch
3.0 star property
Downtown St. Louis
9.4 out of 10, Exceptional, (3283)
"The room was great , the staff was awesome breakfast and evening drinks and food were great overall it was an excellent stay "
United States
Daniel
The price is NT$4,526
NT$5,292 total
includes taxes & fees
Jan 2 - 2026/1/3
Drury Plaza Hotel St. Louis at the Arch
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Central West End Hotel Reviews

Clayton Plaza Hotel & Extended Stay

Clayton Plaza Hotel & Extended Stay

10/10 Excellent
"Yes. The staff was nice and very helpful."
Adrienne 2-night trip
Posted 3 days ago
Clayton Plaza Hotel & Extended Stay

Frequently asked questions

What's Central West End like for family-friendly vacations?
The destination of Central West End is a great choice if you've been thinking about a vacation with your kids. The entertainment, museums, and interesting architecture are just a few things that make this an attractive place for families. Take to the air and fly into St. Louis Lambert Intl. Airport (STL), which is the closest airport, or St. Louis, MO (SUS-Spirit of St. Louis), which is located 20.9 mi (33.7 km) from the center of Central West End.
What's the best hotel for a family trip to Central West End?
Aloft St. Louis Cortex is a hotel with an indoor pool and laundry facilities, and it's a top choice on Expedia for families. AC Hotel St. Louis Central West End is another choice for your kid-friendly vacation.
What's there to see and do with your family in Central West End?
World Chess Hall of Fame and Busch Stadium are interesting attractions you and your family might enjoy exploring while you are staying in Central West End. Make sure you have lots of time for activities like The Muny Theater and Sheldon Concert Hall.

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