Find All Upstate South Carolina Hotels
Change your mindBook hotels with free cancellation
Be pickySearch almost a million properties worldwide
Find All Upstate South Carolina Hotels
We have found 3043 Upstate South Carolina Hotels
- Crowne Plaza Hotel Greenville-I-385-Roper Mtn Rd by IHG
- Hilton Greenville
- Grand Bohemian Lodge Greenville, Autograph Collection
- Best Western Plus Clemson Hotel & Conference Center
- Days Inn by Wyndham Anderson
- Hyatt Regency Greenville
- Embassy Suites Greenville Golf Resort & Conference Center
- Best Western Plus Greenville I-385 Inn & Suites
- Hotel Hartness
- Hyatt Place Greenville Downtown
- La Quinta Inn & Suites by Wyndham Greenville Woodruff Rd.
- Hyatt Place Greenville/Haywood
- Drury Inn & Suites Greenville
- The Shepherd Hotel Downtown Clemson
- Aloft by Marriott Greenville Downtown
- Lakeside Lodge Clemson
- Comfort Inn Greenville - Haywood Mall
- Studio 6 Suites Greenville, SC - Haywood Mall
- La Quinta by Wyndham Haywood Mall-Near Greenville Downtown
- Embassy Suites by Hilton Greenville Downtown Riverplace
- The Westin Poinsett Greenville
- Woodspring Suites Greenville Airport
- Days Inn by Wyndham Greenville
- SpringHill Suites by Marriott Greenville Downtown
- Comfort Suites At WestGate Mall
- Best Western Spartanburg Northwest
- Hampton Inn & Suites Greenville-Downtown-RiverPlace
- Courtyard Marriott Clemson
- Urban Boutique Hotel, BW Signature Collection
- Homewood Suites by Hilton Greenville Downtown
- Quality Inn & Suites Greenville - Haywood Mall
- Inn @ Clemson
- Holiday Inn Express & Suites Greenville - Downtown by IHG
- AC Hotel By Marriott Greenville
- Baymont by Wyndham Greenville Woodruff Rd
- Greenville Inn and Suites
- MainStay Suites Greenville Airport
- Microtel Inn & Suites by Wyndham Greenville / Woodruff Rd
- Studio 6 Greenville, SC
- Clemson University's James F. Martin Inn
- WoodSpring Suites Greenville Central I-85
- Holiday Inn Express Hotel & Suites Spartanburg-North by IHG
- Hampton Inn & Suites Greenville Airport, SC
- Comfort Suites Greenville Airport
- Days Inn by Wyndham Spartanburg Waccamaw
- Comfort Inn & Suites Clemson - University Area
- Fairfield Inn & Suites Seneca Clemson Univ Area
- Spartanburg Marriott
- Fairfield Inn & Suites by Marriott Greenville Simpsonville
- Courtyard by Marriott Greenville Downtown
- AC Hotel by Marriott Spartanburg
- Wingate by Wyndham - Greenville-Airport
- Four Points by Sheraton Spartanburg
- Holiday Inn Express & Suites Greenville Airport by IHG
- Courtyard by Marriott Greenville Haywood Mall
- Quality Inn Seneca Clemson Area US-123
- Tru by Hilton Spartanburg
- Greenville Marriott
- Woodspring Suites Anderson North I-85
- Motel 6 Spartanburg, Sc – Northwest / Business 85
- Rodeway Inn Expo Center
- Courtyard by Marriott Greenville Mauldin
- Motel 6 Greenville, SC
- Holiday Inn Express Hotel & Suites Anderson-I-85 by IHG
- Quality Inn Simpsonville - Greenville
- Hilton Garden Inn Greenville
- The Abernathy of Clemson
- Studio 6 Greenville, SC - I-85 Near Downtown
- Home2 Suites by Hilton Greenville Downtown
- WoodSpring Suites Greenville Haywood Mall
- Holiday Inn Greenville - Woodruff Road by IHG
- WoodSpring Suites Spartanburg - Duncan
- Best Western Plus Spartanburg
- Hampton Inn Gaffney
- Microtel Inn by Wyndham Duncan/Spartanburg
- Quality Inn & Suites Easley - Greenville
- Hampton Inn Greenville I-385 - Woodruff Rd.
- Baymont by Wyndham Easley/Greenville
- Budget Inn Greenville By Hotel O I-85
- Fairfield Inn by Marriott Greenville-Spartanburg Airport
- The Inn at Patrick Square
- Tru by Hilton Seneca Clemson
- Carolina Inn Anderson Clemson Area
- Quality Inn Clemson near University
- Days Inn by Wyndham Easley/Greenville/Clemson Area
- ECHO Suites Extended Stay by Wyndham Spartanburg
- Super 8 by Wyndham Anderson/Clemson Area
- Extended Stay America Premier Suites Greenville Woodruff Rd
- Best Western Travelers Rest Greenville
- Comfort Inn & Suites Greer - Greenville
- Days Inn by Wyndham Clinton / Laurens I-26
- Holiday Inn Express & Suites Greenville-Spartanburg (Duncan) by IHG
- Sleep Inn at Greenville Convention Cente
- Hampton Inn & Suites Seneca-Clemson Area
- Microtel Inn & Suites by Wyndham Anderson/Clemson
- Super 8 by Wyndham Greer/Spartanburg Area
- Courtyard Greenville-Spartanburg by Marriott
- Americas Best Value Inn Anderson, SC
- Holiday Inn Express & Suites Greenville - Taylors by IHG
Let Expedia take you to the best Hotels in Upstate South Carolina. You'll find the largest selection of hotel deals, discount prices, and cheap hotel rates on reservations anywhere in the world. Expedia, the leader in world travel, gives you customer reviews, maps, and the best selection of hotels near landmarks and attractions.