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We have found 310 Murphysboro Hotels
- Holiday Inn Express & Suites Murphysboro - Carbondale by IHG
- Drury Inn & Suites Marion
- Baymont by Wyndham Marion
- Best Western Marion Hotel
- Walker's Bluff Casino Resort
- Best Western Saluki Inn
- Super 8 by Wyndham Marion
- Super 8 by Wyndham Carbondale
- Quality Inn And Suites
- Holiday Inn Carbondale-Conference Center by IHG
- Holiday Inn Express Hotel & Suites Marion Northeast by IHG
- Comfort Inn & Suites Marion I-57
- Econo Lodge
- Country Inn & Suites by Radisson, Marion, IL
- Americas Best Value Inn Marion, IL
- Hampton Inn Carbondale
- Motel 6 Marion, IL
- Fairgrounds Inn
- University Inn of Carbondale
- Home2 Suites by Hilton Carbondale
- Hotel 7 Inn Anna
- Quality Inn Carbondale University area
- Laketree Inn And Suites Marion
- Pinckeyville Inn and Suites
- Fairfield Inn and Suites by Marriott Marion
- Comfort Inn & Suites Carbondale University Area
- Americas Best Value Inn West Frankfort
- Davie School Inn
- Super 8 by Wyndham Du Quoin
- Giant City Lodge
- Makanda Inn
- Gray Plaza Motel
- Carbondale Value Inn & Suites
- Marion Gray Plaza Motel
- Budget Inn Du Quoin
Let Expedia take you to the best Hotels in Murphysboro. You'll find the largest selection of hotel deals, discount prices, and cheap hotel rates on reservations anywhere in the world. Expedia, the leader in world travel, gives you customer reviews, maps, and the best selection of hotels near landmarks and attractions.