Santee 4 Stars Hotels

Start date: Check-in selected.
To Date
End date: Check-out

  • Change your mind

    Book hotels with free cancellation

  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
    Sign in

  • Be picky

    Search almost a million properties worldwide

Check availability on Santee 4 Star Hotels

Tonight
Dec 29 - Dec 30
Tomorrow
Dec 30 - Dec 31
This weekend
Jan 2 - Jan 4
Next weekend
Jan 9 - Jan 11

Our top choices for Santee 4-star hotels

Exterior
Wyndham Vacation Resorts Lake Marion

Wyndham Vacation Resorts Lake Marion

Wyndham Vacation Resorts Lake Marion
4.0 star property
Santee
9.2 out of 10, Wonderful, (21)
"Excellent "
United States
John
Wyndham Vacation Resorts Lake Marion
Save an average of 15% on thousands of hotels when you're signed in
Sign in
Sign up, it's free

Learn more about Santee

Nestled along Lake Marion, this charming town offers prime fishing and boating opportunities for outdoor enthusiasts. Visitors can tee off at Santee National Golf Club or explore nearby Santee State Park's hiking trails and campgrounds.

See all hotels in Santee
Cypress Trees with Spanish Moss growing on them. In Lake Marion at Santee State Park, Santee, Orangeburg County, South Carolina

Top Santee Hotel Reviews

Wyndham Vacation Resorts Lake Marion

Wyndham Vacation Resorts Lake Marion

10/10 Excellent
"Excellent "
John 2-night trip
Posted 3 weeks ago
Wyndham Vacation Resorts Lake Marion

Frequently asked questions

How much does it cost to stay in a 4-star hotel in Santee?
To book a 4-star hotel in Santee that's within your budget, use Expedia's handy filter tool. Browse what's available during your travel dates and use our pricing filter to set your maximum rate. You can also sort your results by the most wallet-friendly option first.

  • Search for the lowest price

What's the difference between 5-star and 4-star hotels in Santee?
Offering a friendly traveler experience and upmarket surroundings, 4-star hotels are a terrific option for your Santee trip. These types of accommodations generally feature loads of useful amenities that make it a breeze to unpack and relax — think large beds, bathrobes, pools and restaurants. Or live in the lap of luxury at a 5-star hotel designed to pamper with luxury perks and amenities. Concierge assistance, complimentary toiletries and world-class dining are typically included at these swanky retreats.
Does Santee have any 4-star all-inclusive resorts?
Finding your dream vacation in Santee is as simple as entering your travel details and selecting our "All inclusive" filter. Stay and play where almost everything is already taken care of like your room, meals and activities, or go for a standard 4-star resort in or around this much-loved destination.

Explore a world of travel with Expedia