An aerial view of a town with industrial buildings, roads, and green areas.

St. Charles 2 Stars Hotels

  • Change your mind

    Book hotels with free cancellation

  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
    Sign in

  • Be picky

    Search almost a million properties worldwide

Check availability on St. Charles 2 Star Hotels

Tonight
Aug 30 - Aug 31
Tomorrow
Aug 31 - Sep 1
Next weekend
Sep 4 - Sep 6
In two weeks
Sep 11 - Sep 13

Our top choices for St. Charles 2-star hotels

An indoor swimming pool with clear water, wooden flooring, and a ceiling with wooden beams and lights.
A hotel room with two beds, a desk, a chair, a television, and a window with curtains.
A café with multiple tables and chairs, a kitchen area with appliances, and a clock on the wall.
A room with a TV mounted on the wall, a wooden table, and two patterned armchairs.

1. Med City Inn & Suites - Mayo Clinic Area

Med City Inn & Suites - Mayo Clinic Area
Kutzky Park
United States
Hailey
NT$2,390
NT$2,752 total
includes taxes & fees
Aug 31 - Sep 1
Med City Inn & Suites - Mayo Clinic Area
A reception area with a wooden reception desk, a "Welcome to the Bread & Butter State" sign, and a "Please Center" sign.
A pool area with a table and chairs, a lifeguard chair, and a pool lift.
A modern lounge area with seating arrangements, a reception desk, and a patterned wall.
A hotel room with a bed, a desk, a chair, a TV, and a bathroom visible through an open door.

2. Hampton Inn Rochester-South

Hampton Inn Rochester-South
Rochester
United States
Lynne
NT$3,215
NT$3,701 total
includes taxes & fees
Sep 7 - Sep 8
Hampton Inn Rochester-South
An indoor swimming pool with slides, seating areas, and a covered section with umbrellas.
A modern kitchen with granite countertops, a built-in microwave, and a sink. There are two wooden chairs and a small table.
A modern kitchen with black cabinets, white countertops, and a tiled backsplash. There are pendant lights, a refrigerator, and a coffee machine.
A hotel room with a kitchen area, a bed, a TV, and a seating area.

3. Best Western Rochester Hotel Mayo Clinic Area/St. Mary's

Best Western Rochester Hotel Mayo Clinic Area/St. Mary's
Rochester
United States
Margita
NT$3,124
NT$3,596 total
includes taxes & fees
Sep 20 - Sep 21
Best Western Rochester Hotel Mayo Clinic Area/St. Mary's
A room with a fireplace, two leather armchairs, a sofa, and a large window providing a view of the outdoors.
A long, narrow hotel corridor with a carpeted floor, light fixtures along the walls, and a ceiling with recessed lighting.
A hotel room with a bed, a sink, a microwave, and a window with curtains.
A reception area with a curved counter, ceiling lights, and a potted plant.

4. Brentwood Inn & Suites

Brentwood Inn & Suites
Downtown Rochester
United States
Bryan
NT$3,952
NT$4,550 total
includes taxes & fees
Sep 3 - Sep 4
Brentwood Inn & Suites
A hotel room with two beds, a desk with a chair, a TV, and a large waterfall painting on the wall.
A reception area with a modern design, featuring a check-in counter, a door, and a small seating area with red stools.
A hotel room with large windows, a clock, and framed pictures on the walls.
An outdoor patio with a table and chairs, a red umbrella, and a view of trees and a sunset.

5. Super 8 by Wyndham Winona MN

Super 8 by Wyndham Winona MN
Winona
United States
Noel
NT$2,024
NT$2,299 total
includes taxes & fees
Sep 20 - Sep 21
Super 8 by Wyndham Winona MN
A hotel lobby with a reception desk, seating area, and a bar.
A front-loading white washer and dryer in a laundry room with a window and a door.
A multi-story hotel with a grey and orange facade, a covered entrance, and a parking lot with marked spaces.
A gym with treadmills, an elliptical, and a stationary bike.

6. Super 8 by Wyndham Rochester Mayo Clinic Area

Super 8 by Wyndham Rochester Mayo Clinic Area
Rochester
United States
Amber
NT$1,720
NT$1,980 total
includes taxes & fees
Sep 6 - Sep 7
Super 8 by Wyndham Rochester Mayo Clinic Area
A restaurant with a staircase, dining tables, chairs, a coffee machine, and a refrigerator.
A spacious living area with a wooden dining table, bar stools, and a patterned armchair. A staircase leads to an upper level with a balcony.
A spacious lobby with a high ceiling, a central seating area with patterned sofas and ottomans, a reception desk, and a staircase leading to an upper level.

7. Quality Inn near Medical Center

Quality Inn near Medical Center
Rochester
United States
Connie
NT$1,989
NT$2,290 total
includes taxes & fees
Sep 20 - Sep 21
Quality Inn near Medical Center
A hotel room with a large bed, a desk, a chair, a TV, and a window with curtains.
A hotel room with a large window, a clock, a framed picture of pottery, a desk with a computer, and a seating area with patterned chairs.
A compact hotel room with a kitchenette, a dining area, a sofa, and a bed.
A Microtel Inn & Suites building with a signboard, a parking lot, and a clear sky.

8. Microtel Inn & Suites by Wyndham Rochester North Mayo Clinic

Microtel Inn & Suites by Wyndham Rochester North Mayo Clinic
Rochester
United States
Siddhartha
NT$2,204
NT$2,538 total
includes taxes & fees
Sep 1 - Sep 2
Microtel Inn & Suites by Wyndham Rochester North Mayo Clinic
A self-service breakfast station with a waffle maker, coffee machines, and a variety of condiments.
A compact laundry area with a washing machine, dryer, and a water fountain.
A hotel lobby with leather sofas, a stone fireplace, and a patterned carpet.
A hotel room with a large bed, a desk, a chair, a television, and a window with curtains.

9. Econo Lodge Mayo Clinic Area

Econo Lodge Mayo Clinic Area
Rochester
United States
Markus
NT$2,167
NT$2,495 total
includes taxes & fees
Sep 20 - Sep 21
Econo Lodge Mayo Clinic Area
A hotel room with a large bed, a desk with a chair, a window with a view of the outdoors, and two bedside lamps.
A gym with treadmills, elliptical machines, and a stationary bike.

10. Comfort Inn & Suites Rochester South Mayo Clinic

Comfort Inn & Suites Rochester South Mayo Clinic
Rochester
United States
Deborah
NT$2,623
NT$3,020 total
includes taxes & fees
Sep 30 - Oct 1
Comfort Inn & Suites Rochester South Mayo Clinic
A modern hotel lobby with a reception desk, seating area, and a dining space.
A modern hotel room with a wooden desk, orange chair, dark sofa, and a small table.
A Holiday Inn Express building with a stone facade and illuminated signage.
A hotel room with a bed, desk, chair, and a bathroom.

11. Holiday Inn Express Rochester South - Mayo Area by IHG

Holiday Inn Express Rochester South - Mayo Area by IHG
Rochester
United States
Stephanie
NT$3,225
NT$3,713 total
includes taxes & fees
Sep 27 - Sep 28
Holiday Inn Express Rochester South - Mayo Area by IHG
A spacious lobby with a reception desk, sofas, and a coffee table.
A Sleep Inn hotel with a covered entrance, stone pillars, and a clear blue sky.
An indoor swimming pool with clear blue water, surrounded by tiled flooring and equipped with a pool ladder.
A hotel room with a large bed, a sofa, a TV, and a desk.

12. Sleep Inn & Suites West-Near Medical Center

Sleep Inn & Suites West-Near Medical Center
Rochester
United States
Kaitlin
NT$2,626
NT$3,023 total
includes taxes & fees
Sep 20 - Sep 21
Sleep Inn & Suites West-Near Medical Center

13. Birch Hill Suite Rochester – Med City

Birch Hill Suite Rochester – Med City
Rochester
United States
Jerrod
NT$1,884
NT$2,169 total
includes taxes & fees
Sep 28 - Sep 29
Birch Hill Suite Rochester – Med City
A hotel room with a large bed, a desk with a chair, a television, and a view of the outdoors through a door.
A compact hotel room with a kitchenette, a leather chair, and a view of the balcony.
An indoor swimming pool with clear blue water, a ladder, and blue chairs around the pool.
A hotel room with a large bed, a desk, a chair, and a TV.

14. Baymont by Wyndham Rochester Mayo Clinic Area

Baymont by Wyndham Rochester Mayo Clinic Area
Rochester
United States
Bobbi
NT$1,882
NT$2,166 total
includes taxes & fees
Sep 6 - Sep 7
Baymont by Wyndham Rochester Mayo Clinic Area
A hotel room with two beds, a large landscape painting above the headboard, a bedside table with a phone, and a blue patterned rug.
A breakfast area with a coffee station, a refrigerator, and a dining table with chairs.
A gym with treadmills, an elliptical, and a stationary bike.
A modern room with two sofas, a coffee table, and large windows with curtains.

15. Days Inn by Wyndham Winona

Days Inn by Wyndham Winona
Winona
United States
LeAndre
NT$2,150
NT$2,400 total
includes taxes & fees
Sep 6 - Sep 7
Days Inn by Wyndham Winona
A modern dining area with high tables, chairs, and pendant lighting.
A reception desk with a large digital screen displaying a cityscape and the word "happy."
A swimming pool with a tiled deck, sun loungers, and a lifeguard chair.
A hotel room with two beds, a desk with a computer, a chair, and a window with a view.

16. Hampton Inn & Suites Rochester-North

Hampton Inn & Suites Rochester-North
Rochester
United States
Albert
NT$3,085
NT$3,552 total
includes taxes & fees
Sep 5 - Sep 6
Hampton Inn & Suites Rochester-North
A Holiday Inn Express building with a covered entrance, outdoor seating area, and a well-lit facade.
A coffee station with two espresso machines and a variety of coffee pods and cups.
A swimming pool with a lifeguard sign, tiled walls, and a clear blue pool.
A hotel reception area with a reception desk, a waiting area with a sofa, and a clear view of the lobby.

17. Holiday Inn Express & Suites Rochester – Mayo Clinic Area by IHG

Holiday Inn Express & Suites Rochester – Mayo Clinic Area by IHG
Kutzky Park
United States
Janet
NT$3,415
NT$3,931 total
includes taxes & fees
Sep 4 - Sep 5
Holiday Inn Express & Suites Rochester – Mayo Clinic Area by IHG
A hotel lobby with two leather armchairs, a small round table, a 'WELCOME' sign, and a 'TRASH CAN' sign on the wall.
A multi-story hotel with a brick facade, a covered lobby entrance, and a parking lot with several cars.
A hotel reception area with a black reception desk, a 'WELCOME' sign, a bench, and two armchairs.

18. Extended Stay America Suites Rochester North

Extended Stay America Suites Rochester North
Rochester
United States
Rick
NT$2,162
NT$2,489 total
includes taxes & fees
Aug 31 - Sep 1
Extended Stay America Suites Rochester North
A reception desk with a digital display, a fire extinguisher, and a framed welcome sign.
A hotel indoor pool with clear water, lounge chairs, and a seating area with an umbrella.

19. Holiday Inn Express & Suites Winona by IHG

Holiday Inn Express & Suites Winona by IHG
Winona
United States
Leiann
NT$3,858
NT$4,306 total
includes taxes & fees
Sep 13 - Sep 14
Holiday Inn Express & Suites Winona by IHG
A hotel room with a large bed, bedside tables, a wall-mounted light, and a window with curtains.
A reception area with a counter, seating, a plant, and informational signs.
A compact hotel room with a kitchenette, a flat-screen TV, a desk with a chair, and a trash bin.
A hotel lobby with a view of a swimming pool, a bench, and a potted plant.

20. Motel 6 Rochester, MN

Motel 6 Rochester, MN
Rochester
United States
Jon
NT$1,565
NT$1,801 total
includes taxes & fees
Sep 2 - Sep 3
Motel 6 Rochester, MN
Save an average of 15% on thousands of hotels when you're signed in

Explore similar 3-star hotels

Many 3-star hotels have the same amenities as 2-star hotels. See all 3-star hotels in St. Charles.
Kahler Grand Hotel

Kahler Grand Hotel

20 2nd Ave Sw Rochester MN
Get rates
8.4/10 Very Good! (2,288 reviews)
Kahler Grand Hotel
Kahler Inn and Suites - Mayo Clinic Area

Kahler Inn and Suites - Mayo Clinic Area

9 3rd Ave Nw Rochester MN
NT$3,956
NT$4,554 total
Sep 4 - Sep 5
includes taxes & fees
8.2/10 Very Good! (1,693 reviews)
Kahler Inn and Suites - Mayo Clinic Area
Centerstone Plaza Hotel Soldiers Field - Mayo Clinic Area

Centerstone Plaza Hotel Soldiers Field - Mayo Clinic Area

401 6th St Sw Rochester MN
NT$3,611
NT$4,157 total
Sep 6 - Sep 7
includes taxes & fees
Centerstone Plaza Hotel Soldiers Field - Mayo Clinic Area
Still don't see what you're looking for?
See all properties in St. Charles.
You can also use these popular filters to refine your search.
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Learn more about St. Charles

St. Charles awaits: its natural setting and more!

See all hotels in St. Charles
An aerial view of a town with industrial buildings, roads, and green areas.

Top St. Charles Hotel Reviews

Green Gables Inn

Green Gables Inn

10/10 Excellent
"Wonderful property. Comfortable beds. Gorgeous grounds on the river. Brian & Tracy were very welcoming"
MaryPat 1-night trip
Posted 18 hours ago
Green Gables Inn

Explore a world of travel with Expedia