An aerial view of a coastal landscape with a dam, farmland, and dense forests.

Santee 2 Stars Hotels

  • Change your mind

    Book hotels with free cancellation

  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
    Sign in

  • Be picky

    Search almost a million properties worldwide

Check availability on Santee 2 Star Hotels

Tonight
Sep 10 - Sep 11
Tomorrow
Sep 11 - Sep 12
This weekend
Sep 11 - Sep 13
Next weekend
Sep 18 - Sep 20

Our top choices for Santee 2-star hotels

A breakfast area with a self-service counter, refrigerated display, and a digital menu board.
A modern hotel with a blue and white facade, a covered entrance, and palm trees in front.
A hotel room with two beds, a desk, and a large window with a view.
A modern lobby with a blue sofa, teal chairs, and a wooden table.

1. Tru By Hilton Santee

Tru By Hilton Santee
Santee
United States
Vicky L
NT$3,070
NT$3,408 total
includes taxes & fees
Sep 20 - Sep 21
Tru By Hilton Santee
A hotel room with two beds, a grey armchair, a nightstand with a phone, and a cityscape picture on the wall.
A spacious dining area with multiple tables and chairs, large windows, and a patterned carpet.
A lobby with two leather armchairs, a marble-topped table, and a patterned carpet.
A Baymont by Wyndham hotel with a blue and yellow facade, a covered parking area, and a large parking lot.

2. Baymont by Wyndham Santee

Baymont by Wyndham Santee
Santee
United States
Yomerys
NT$2,517
NT$2,794 total
includes taxes & fees
Sep 17 - Sep 18
Baymont by Wyndham Santee
A self-service kiosk with a beverage cooler, microwave, and various food items.
A modern interior with a dining area, seating arrangements, and a reception desk.
A breakfast counter with a sign reading 'TOP IT BREAKFAST,' a coffee machine, a yogurt dispenser, and various food items.
A modern hotel lobby with a reception desk, blue and gray seating, a TV screen, and unique pendant lighting.

3. Tru by Hilton Orangeburg

Tru by Hilton Orangeburg
Orangeburg
Canada
Andrew
NT$3,586
NT$3,981 total
includes taxes & fees
Sep 29 - Sep 30
Tru by Hilton Orangeburg
A hotel room with two beds, a desk, a chair, and a mirror.
A wooden pergola with a bench, a well-maintained lawn, and a parking area with buildings in the background.
A modern cafe with a stone backsplash, wooden cabinets, and yellow chairs.
A living room with a sofa, armchair, coffee table, and a flat-screen TV mounted on the wall.

4. SureStay Hotel by Best Western Manning

SureStay Hotel by Best Western Manning
Manning
United States
Christopher
NT$2,576
NT$2,860 total
includes taxes & fees
Sep 23 - Sep 24
SureStay Hotel by Best Western Manning
A modern indoor pool area with a table and chairs, large windows, and a poolside lounge with sun loungers.
A lobby with a reception desk, a staircase, and seating area with orange chairs.
A modern indoor swimming pool with clear glass walls, sunlit lounge areas, and a view of greenery outside.
A hotel with a modern design, featuring a prominent 'Spark' sign, a well-maintained lawn, and a clear driveway.

5. Spark by Hilton Orangeburg

Spark by Hilton Orangeburg
Orangeburg
United States
TaNikka
NT$3,070
NT$3,408 total
includes taxes & fees
Sep 13 - Sep 14
Spark by Hilton Orangeburg
A two-story building with a sign reading "PachTree Inn".
A reception desk with a clock, framed certificates, and a window with a view.
A compact hotel room with a kitchenette, a television, a desk, and a chair.
A hotel room with two beds, a nightstand, a lamp, a chair, and a painting on the wall.

6. Peach Tree Inn

Peach Tree Inn
St. George
United States
Linda
NT$2,033
NT$2,195 total
includes taxes & fees
Oct 4 - Oct 5
Peach Tree Inn
A hotel room with a large bed, a desk, a chair, a desk lamp, and a wall-mounted lamp.
A modern living room with teal and orange chairs, a grey sofa, a fireplace, and a staircase.
A room with a black console table displaying coffee and tea options, a large window, and a sliding glass door leading to a dining area with red chairs.
A modern living room with a sofa, a red ottoman, a TV mounted on the wall, and a wooden entertainment unit.

7. Comfort Inn & Suites Santee

Comfort Inn & Suites Santee
Santee
United States
santa
NT$3,256
NT$3,615 total
includes taxes & fees
Oct 4 - Oct 5
Comfort Inn & Suites Santee
A spacious dining area with multiple tables and chairs, a reception desk, and large windows providing natural light.
A hotel room with two beds, a seating area, and a large abstract painting on the wall.
A modern hotel room with a grey sofa, a flat-screen TV, a desk with a lamp, and abstract wall art.
A modern lobby with a wooden ceiling, a central seating area with a round table, and a bar with a variety of bottles.

8. SpringHill Suites by Marriott Orangeburg

SpringHill Suites by Marriott Orangeburg
Orangeburg
United States
Henrietta
NT$3,434
NT$3,812 total
includes taxes & fees
Sep 21 - Sep 22
SpringHill Suites by Marriott Orangeburg
A hotel room with a bed, a desk, a chair, a sofa, and a table.
A gym with cardio equipment, dumbbells, and a TV on a shelf.
A hotel with a swimming pool, outdoor seating, and a flagpole with an American flag.
A breakfast corner with wooden tables and chairs, a coffee machine, and a sign indicating breakfast hours.

9. Baymont by Wyndham Orangeburg North

Baymont by Wyndham Orangeburg North
Orangeburg
United States
SHERRY
NT$1,768
NT$1,963 total
includes taxes & fees
Sep 20 - Sep 21
Baymont by Wyndham Orangeburg North
A hotel dining area with multiple tables and chairs, a large flat-screen TV, and a patterned wall design.
A Hampton Inn hotel at night with a well-lit facade and a parking lot in the foreground.
A modern hotel with a swimming pool, outdoor seating, and a sign reading "Hampton Inn".
A hotel room with a bed, desk, chair, lamp, kitchenette, and a door.

10. Hampton Inn Santee-I-95

Hampton Inn Santee-I-95
Santee
United States
Janice
NT$3,929
NT$4,362 total
includes taxes & fees
Sep 20 - Sep 21
Hampton Inn Santee-I-95
A hotel lobby with a large potted plant, a blue armchair, a dining area with chairs and a table, and a red doormat with the hotel name.
A compact kitchen with wooden cabinets, a microwave, and a dining area with purple chairs.
A hotel room with a large window, a blue sofa, a wooden table, and a blue and white accent wall.
A compact living space with a dining area, kitchenette, and a large window with blinds.

11. Econo Lodge St. George

Econo Lodge St. George
St. George
United States
Fred
NT$2,113
NT$2,282 total
includes taxes & fees
Oct 4 - Oct 5
Econo Lodge St. George
A breakfast bar with pastries, fruits, and a vase with flowers.
A hotel room with two beds, a nightstand, and two wall-mounted lamps.
A hotel bathroom with a sink, mirror, towel rack, and a door leading to the bedroom.
A reception area with a dark-colored reception desk, a clock on the wall, and a doormat with "Travelodge" written on it.

12. Travelodge by Wyndham Orangeburg

Travelodge by Wyndham Orangeburg
Orangeburg
United States
Arsenio
NT$2,360
NT$2,620 total
includes taxes & fees
Oct 4 - Oct 5
Travelodge by Wyndham Orangeburg
A Red Roof Inn with two red leather armchairs and a small wooden table in front of a stone-patterned wall.
A two-story building with a grey facade, large windows, and a covered entrance area.
A hotel reception area with a counter, coffee machines, and a refrigerator.
A reception desk with a digital screen displaying 'Welcome' and 'Red Roof Inn.' There is a clock on the wall, a window with a view of a parking lot, and a refrigerator with 'Carolina's' branding.

13. Red Roof Inn Orangeburg

Red Roof Inn Orangeburg
Orangeburg
United States
Amanda
NT$1,840
NT$2,043 total
includes taxes & fees
Sep 17 - Sep 18
Red Roof Inn Orangeburg
A hotel room with two beds, a desk, and a chair. There are wall-mounted lamps and a large window with curtains.
A Comfort Inn & Suites hotel with a brick facade, multiple windows, and a clear blue sky.
A swimming pool with a 4ft depth marker, lounge chairs, and a covered seating area.
A reception area with a wooden reception desk, a wall-mounted clock, and a welcome mat.

14. Comfort Inn & Suites Orangeburg

Comfort Inn & Suites Orangeburg
Orangeburg
United States
Barry
NT$2,947
NT$3,271 total
includes taxes & fees
Oct 2 - Oct 3
Comfort Inn & Suites Orangeburg
A hotel entrance with a sign reading "Best Western PLISS."
A spacious kitchen with white cabinets, a dining area with red patterned chairs, and a fireplace.
A modern kitchen with a red accent wall, white cabinetry, and a built-in espresso machine.
A hotel room with two large beds, a wooden headboard, bedside tables with lamps, a wardrobe, and a view of the outdoors through a window.

15. Best Western Plus Santee Inn

Best Western Plus Santee Inn
Santee
United States
Bonnie
NT$3,477
NT$3,860 total
includes taxes & fees
Sep 20 - Sep 21
Best Western Plus Santee Inn
A Hampton Inn & Suites hotel with a modern design, featuring a parking lot and a well-lit entrance.
A snack shop with a sign reading "Hampton Suite Shop" and a variety of snacks and drinks on display.
A gym with treadmills, a bench, and a ball.
A hotel room with a large bed, a desk with a flat-screen TV, a chair, a desk lamp, and a window with curtains.

16. Hampton Inn & Suites Orangeburg

Hampton Inn & Suites Orangeburg
Orangeburg
United States
JORDAN
NT$4,103
NT$4,554 total
includes taxes & fees
Sep 27 - Sep 28
Hampton Inn & Suites Orangeburg
A spacious living area with a large sofa, multiple armchairs, and a wooden coffee table.
A hotel room with a bed, a desk with a television, a microwave, a refrigerator, and a chair.
A reception area with a wooden counter, a sofa, a desk with a statue, and framed pictures on the wall.
A living room with beige sofas, a coffee table, and two armchairs. There are large windows with curtains, a flat-screen TV mounted on the wall, and a small rug on the floor.

17. Budget Inn By Belvilla St George I-95

Budget Inn By Belvilla St George I-95
St. George
United States
alain
NT$1,635
NT$1,979 total
includes taxes & fees
Oct 4 - Oct 5
Budget Inn By Belvilla St George I-95
A lobby with a reception desk, a sofa, a small round table, and an American flag.
A hotel room with a large bed, a desk, a chair, a nightstand, and a wall-mounted lamp.
A Holiday Inn Express & Suites building with a clear entrance, a covered waiting area, and a landscaped garden.
A modern hotel lobby with a reception desk, seating area, and a coffee bar.

18. Holiday Inn Express & Suites Orangeburg by IHG

Holiday Inn Express & Suites Orangeburg by IHG
Orangeburg
United States
Jenelyn
NT$3,241
NT$3,598 total
includes taxes & fees
Oct 11 - Oct 12
Holiday Inn Express & Suites Orangeburg by IHG
A hotel room with two beds, a desk, a mirror, and a wall-mounted TV.
A motel with a brick facade, a covered entrance, and a satellite dish.
A kitchen with a countertop, cabinets, a microwave, and a sink.
A room with a flat-screen TV mounted on the wall, a small round table with a computer and keyboard, a chair, and a framed picture above the table.

19. Travelodge by Wyndham Santee

Travelodge by Wyndham Santee
Santee
United States
Mark
NT$2,014
NT$2,235 total
includes taxes & fees
Oct 11 - Oct 12
Travelodge by Wyndham Santee
A hotel lobby with a reception desk, seating area, and a large potted plant.
A hotel room with two beds, a TV, a desk, and a chair.
A hotel lobby with multiple seating areas, a reception desk, and a television.
A Hampton Inn hotel with a clear sky.

20. Hampton Inn Manning

Hampton Inn Manning
Manning
United States
ANTHONY G
NT$4,257
NT$4,726 total
includes taxes & fees
Sep 20 - Sep 21
Hampton Inn Manning
Save an average of 15% on thousands of hotels when you're signed in

Explore similar 3-star hotels

Many 3-star hotels have the same amenities as 2-star hotels. See all 3-star hotels in Santee.
Fairfield Inn & Suites by Marriott Santee

Fairfield Inn & Suites by Marriott Santee

9074 Old Number Six Hwy Santee SC
NT$4,220
NT$4,684 total
Sep 21 - Sep 22
includes taxes & fees
Fairfield Inn & Suites by Marriott Santee
Fairfield Inn by Marriott Orangeburg

Fairfield Inn by Marriott Orangeburg

663 Citadel Road Orangeburg SC
NT$3,317
NT$3,681 total
Sep 17 - Sep 18
includes taxes & fees
8.4/10 Very Good! (824 reviews)
Fairfield Inn by Marriott Orangeburg
Holiday Inn Santee by IHG

Holiday Inn Santee by IHG

139 Bradford Blvd Santee SC
NT$3,304
NT$3,667 total
Oct 4 - Oct 5
includes taxes & fees
Holiday Inn Santee by IHG
Still don't see what you're looking for?
See all properties in Santee.
You can also use these popular filters to refine your search.
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Learn more about Santee

Nestled along Lake Marion, this charming town offers prime fishing and boating opportunities for outdoor enthusiasts. Visitors can tee off at Santee National Golf Club or explore nearby Santee State Park's hiking trails and campgrounds.

See all hotels in Santee
A tree with Spanish moss and autumn leaves in a body of water.

Top Santee Hotel Reviews

Red Roof Inn Santee

Red Roof Inn Santee

10/10 Excellent
"Nice place. Clean & mattress was super comfy!"
Karyn 1-night trip
Posted 3 days ago
Red Roof Inn Santee
Travelodge by Wyndham Santee

Travelodge by Wyndham Santee

10/10 Excellent
"Love the location very friendly and clean. I love they have high security on site"
fern 1-night trip
Posted 12 days ago
Travelodge by Wyndham Santee
Ramada by Wyndham Santee I-95

Ramada by Wyndham Santee I-95

8/10 Good
"The price rate was great"
Stevenson 3-night trip
Posted 1 month ago
Ramada by Wyndham Santee I-95

Explore a world of travel with Expedia