Photo by Ryan Watts

Find hotels in Upstate South Carolina, SC from NT$2,232
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Go beyond your typical stay in Upstate South Carolina
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Check prices for these dates
Our top choices for Upstate South Carolina hotels

Carolina Inn Anderson Clemson Area
Carolina Inn Anderson Clemson AreaAnderson
The price is NT$1,728
NT$1,918 total
includes taxes & fees
May 20 - May 21

Deluxe Inn
Deluxe InnMauldin
10.0 out of 10, Exceptional, (2 reviews)
The price is NT$2,199
NT$2,418 total
includes taxes & fees
May 16 - May 17

Clemson University's James F. Martin Inn
Clemson University's James F. Martin InnClemson
9.4 out of 10, Exceptional, (1,007 reviews)
The price is NT$4,680
NT$5,195 total
includes taxes & fees
May 13 - May 14

Carolina Camp Cedar
Carolina Camp CedarPickens
10.0 out of 10, Exceptional, (3 reviews)
The price is NT$5,308
NT$8,507 total
includes taxes & fees
May 17 - May 18

Lakeside Lodge Clemson
Lakeside Lodge ClemsonSeneca
9.0 out of 10, Wonderful, (1,007 reviews)
The price is NT$3,424
NT$4,250 total
includes taxes & fees
May 17 - May 18

Quality Inn Seneca Clemson Area US-123
Quality Inn Seneca Clemson Area US-123Downtown
8.0 out of 10, Very Good, (698 reviews)
The price is NT$2,583
NT$3,037 total
includes taxes & fees
Jun 4 - Jun 5

Inn on the Square, an Ascend Collection Hotel
Inn on the Square, an Ascend Collection HotelUptown Greenwood
9.2 out of 10, Wonderful, (736 reviews)
The price is NT$3,929
NT$4,361 total
includes taxes & fees
May 24 - May 25

Fairfield Inn & Suites Seneca Clemson Univ Area
Fairfield Inn & Suites Seneca Clemson Univ AreaSeneca
9.4 out of 10, Exceptional, (229 reviews)
The price is NT$4,060
NT$4,466 total
includes taxes & fees
May 18 - May 19

Hampton Inn Gaffney
Hampton Inn GaffneyGaffney
8.8 out of 10, Excellent, (710 reviews)
The price is NT$2,670
NT$2,910 total
includes taxes & fees
May 17 - May 18

Clemson Memorabilia House
Clemson Memorabilia HouseClemson
9.6 out of 10, Exceptional, (10 reviews)
The price is NT$2,795
NT$7,461 total
includes taxes & fees
May 17 - May 18

Hampton Inn Greer Greenville, SC
Hampton Inn Greer Greenville, SCGreer
9.6 out of 10, Exceptional, (454 reviews)
The price is NT$4,366
NT$4,759 total
includes taxes & fees
Jun 7 - Jun 8

Best Western Plus Clemson Hotel & Conference Center
Best Western Plus Clemson Hotel & Conference CenterClemson
8.2 out of 10, Very Good, (1,014 reviews)
The price is NT$3,444
NT$3,823 total
includes taxes & fees
May 24 - May 25

Comfort Inn & Suites Greer - Greenville
Comfort Inn & Suites Greer - GreenvilleGreer
8.6 out of 10, Excellent, (788 reviews)
The price is NT$3,196
NT$3,580 total
includes taxes & fees
May 25 - May 26

Holiday Inn Express Hotel & Suites Anderson-I-85 by IHG
Holiday Inn Express Hotel & Suites Anderson-I-85 by IHGAnderson
9.2 out of 10, Wonderful, (614 reviews)
The price is NT$3,455
NT$3,835 total
includes taxes & fees
May 17 - May 18

Microtel Inn & Suites by Wyndham Anderson/Clemson
Microtel Inn & Suites by Wyndham Anderson/ClemsonAnderson
8.2 out of 10, Very Good, (1,010 reviews)
The price is NT$2,643
NT$2,934 total
includes taxes & fees
May 18 - May 19

Quality Inn Clinton - Laurens I-26
Quality Inn Clinton - Laurens I-26Clinton
7.4 out of 10, Good, (548 reviews)
The price is NT$1,979
NT$2,322 total
includes taxes & fees
Jun 7 - Jun 8

Comfort Inn & Suites Clemson - University Area
Comfort Inn & Suites Clemson - University AreaClemson
8.4 out of 10, Very Good, (1,013 reviews)
The price is NT$3,177
NT$3,526 total
includes taxes & fees
Jun 9 - Jun 10

Tru by Hilton Seneca Clemson
Tru by Hilton Seneca ClemsonSeneca
9.2 out of 10, Wonderful, (839 reviews)
The price is NT$3,580
NT$3,938 total
includes taxes & fees
Jun 8 - Jun 9

Hampton Inn & Suites Clinton - I-26
Hampton Inn & Suites Clinton - I-26Clinton
9.0 out of 10, Wonderful, (736 reviews)
The price is NT$3,684
NT$4,126 total
includes taxes & fees
May 24 - May 25

The Inn at Patrick Square
The Inn at Patrick SquareClemson
9.8 out of 10, Exceptional, (845 reviews)
The price is NT$4,994
NT$5,543 total
includes taxes & fees
May 14 - May 15
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Vacation Rentals in Upstate South Carolina
Cabin

Postcard Cabins Lake Hartwell, Outdoor Collection by Marriott Bonvoy
Postcard Cabins Lake Hartwell, Outdoor Collection by Marriott BonvoySeneca
9.8 out of 10, Exceptional, (72 reviews)
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Stay near popular Upstate South Carolina attractions
Learn more about Upstate South Carolina
Venture to sights like Discovery Island Water Park and Heritage Park as you discover Upstate South Carolina.

Photo by Ryan Watts
Open Photo by Ryan Watts
Top Upstate South Carolina Hotel Reviews

Homewood Suites by Hilton Greenville Downtown
10/10 Excellent
More cheap stays in Upstate South Carolina

Days Inn by Wyndham Greenville
60 Roper Mountain Rd Greenville SC
The price is NT$2,029 per night from May 17 to May 18
NT$2,029
NT$2,232 total
May 17 - May 18
includes taxes & fees
5.6/10 (1,016 reviews)
Hotels in Upstate South Carolina with star-rating

4 Star Hotels
31 properties
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