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Find Resorts & Hotels with Spas in St. Charles, MO

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Check availability on St. Charles Resorts & Hotels with Spas

Tonight
Oct 11 - Oct 12
Tomorrow
Oct 12 - Oct 13
Next weekend
Oct 16 - Oct 18
In two weeks
Oct 23 - Oct 25

Our top choices for St. Charles hotels with a spa

A modern spa with a curved reception desk, a large mirror, and a decorative water feature.
A bar area with multiple seating arrangements, a stage, and a chandelier.
An indoor swimming pool with clear glass walls, metal railings, and a tiled floor.
A modern tavern with a large sign, glass doors, and indoor seating visible through the windows.

1. Ameristar Casino Resort and Spa

Ameristar Casino Resort and Spa
St. Charles
  • Riverside wellness oasis offers full-service spa with aromatherapy and hydrotherapy for a restorative retreat.
NT$5,718
NT$7,213 total
includes taxes & fees
Oct 12 - Oct 13
Ameristar Casino Resort and Spa
A reception desk with a wooden finish and the name "IDOL WOLF" on it.
A reception area with a curved wooden desk, a laptop, and a chair. The wall has a sign reading "Locust Street Athletic and Swim Club."
A spacious lobby with a large spherical sculpture, a seating area, and a view of the outside through a large window.
A multi-story building with a symmetrical facade, large windows, and a central entrance with a canopy.

2. 21C Museum Hotel St Louis

21C Museum Hotel St Louis
Downtown West
  • Discover spa services, a steam room, and an Olympic-sized indoor pool at this modern hotel, all designed for rejuvenating getaways.
NT$4,586
NT$5,522 total
includes taxes & fees
Nov 1 - Nov 2
21C Museum Hotel St Louis
A modern kitchen with wooden cabinets, a central island, and framed artwork on the walls.
An indoor dining area with a long table, chairs, hanging plants, and a view of a brick building through large windows.
A bar area with leather seating, a bar counter, and shelves of bottles.
A couple standing on a balcony with a cityscape view.

3. The Ritz-Carlton, St. Louis

The Ritz-Carlton, St. Louis
Clayton
  • Revel in a rejuvenating spa retreat with aromatherapy treatments and hot stone massages at this luxury St. Louis hotel.
NT$18,485
NT$21,579 total
includes taxes & fees
Nov 1 - Nov 2
The Ritz-Carlton, St. Louis
A couple relaxing by a window overlooking a bridge and water.
A room with large windows overlooking a bridge and water, featuring wooden chairs and a small table.
A bar area with a bartender, a bar counter with various bottles, and a view of the Gateway Arch.
A modern dining area with a long table set for a meal, large windows offering a view of a bridge, and a stone accent wall.

4. Four Seasons Hotel St Louis

Four Seasons Hotel St Louis
Downtown St. Louis
  • Discover a tranquil haven with 12 treatment rooms, outdoor pool, and breathtaking views at this rejuvenating spa retreat.
NT$11,972
NT$13,999 total
includes taxes & fees
Oct 12 - Oct 13
Four Seasons Hotel St Louis
A bathroom with a white sink, dark wooden door, and a shower area with striped glass walls.
A modern interior with a staircase, a large abstract painting, and a seating area with a glass coffee table.
A two-story building with a dark entrance, large windows, and a brick facade.
A room with a bed, a nightstand with a lamp, a painting on the wall, and a radiator.

5. Truitt Hotel

Truitt Hotel
Lafayette Square
NT$5,364
NT$6,511 total
includes taxes & fees
Oct 12 - Oct 13
Truitt Hotel
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Choose what matters most at spa hotels in St. Charles

Pool
Hot tub
Breakfast included
4 stars
5 stars

Find out more about St. Charles

Top St. Charles attractions for a relaxing vacation

St. Charles, Missouri offers a delightful blend of relaxation and adventure for travelers seeking hotels with spas. Start your journey with a visit to the historic Main Street, lined with charming boutiques, restaurants, and art galleries, perfect for a leisurely stroll after a rejuvenating spa session. The nearby Frontier Park provides scenic river views and walking trails, ideal for unwinding and connecting with nature. Families can enjoy a day at the St. Charles City Parks, which feature playgrounds and picnic areas, making it a great spot for children to play while parents indulge in some pampering. For a unique experience, consider exploring the local wineries; many offer tastings and tours with tranquil surroundings that enhance your relaxation. After a day of activities, retreat to a spa hotel in the heart of the historic district, where you can enjoy top amenities and attentive service, ensuring you feel pampered throughout your stay.

Find the best hotels & resorts with spas in St. Charles

For those seeking relaxation and rejuvenation in St. Charles, Missouri, these top hotels offer exceptional spa amenities that promise a tranquil escape. Discover the perfect haven to unwind and pamper yourself during your stay.Ameristar Casino Resort and Spa

  • Why it's great for tailored spa getaway: Ameristar Casino Resort and Spa stands out as a premier destination for travelers seeking a luxurious spa experience, an excellent guest review rating of 8.4. This resort features a full-service spa where guests can indulge in an array of treatments including body treatments, massages, and hydrotherapy sessions, ensuring a rejuvenating retreat right at their fingertips.
  • Other amenities: In addition to its spa offerings, the resort provides a wealth of amenities to enhance every guest's stay. Guests can enjoy the soothing ambiance of the hot tub, relax by the resort pool, or take advantage of fitness facilities open 24 hours. The hotel also features a poolside bar for refreshing drinks, onsite dining options, and concierge services to help plan the perfect getaway. With nearby winery tours and golf opportunities, guests have plenty of options to explore beyond the spa.
  • Nearby attractions: Ameristar Casino St. Charles - 0.01 miles, Historic Main Street - 0.68 miles, Lewis & Clark Boathouse and Nature Center - 0.71 miles

Top St. Charles Hotel Reviews

Pear Tree Inn St. Louis Near Union Station

Pear Tree Inn St. Louis Near Union Station

8/10 Good
"friendly staff, great for kids"
Samantha 2-night trip
Posted less than an hour ago
Pear Tree Inn St. Louis Near Union Station
Drury Plaza Hotel St. Louis Union Station

Drury Plaza Hotel St. Louis Union Station

10/10 Excellent
"Bed very comfortable, clean room, staff friendly and helpful. Good location. Food in evening was amazing. Breakfast buffet was good, about like other hotels as far as choices, nicely setup tho."
Linda 1-night trip
Posted 1 hour ago
Drury Plaza Hotel St. Louis Union Station
Clayton Plaza Hotel & Extended Stay

Clayton Plaza Hotel & Extended Stay

10/10 Excellent
"Good breakfast, nice service, nice room! Really good shower too, let you set the temperature"
Sarah 2-night trip
Posted 2 hours ago
Clayton Plaza Hotel & Extended Stay
Drury Plaza Hotel St. Louis at the Arch

Drury Plaza Hotel St. Louis at the Arch

10/10 Excellent
"Clean room good breakfast"
amber 1-night trip
Posted 3 hours ago
Drury Plaza Hotel St. Louis at the Arch
Embassy Suites by Hilton St. Louis St. Charles

Embassy Suites by Hilton St. Louis St. Charles

10/10 Excellent
"Great place to stay"
Elyse 3-night trip
Posted 21 hours ago
Embassy Suites by Hilton St. Louis St. Charles
Country Inn & Suites by Radisson, St. Charles Historic District

Country Inn & Suites by Radisson, St. Charles Historic District

10/10 Excellent
"All good and lovely staff"
Heidi 4-night trip
Posted 1 day ago
Country Inn & Suites by Radisson, St. Charles Historic District
Ameristar Casino Resort and Spa

Ameristar Casino Resort and Spa

8/10 Good
"Wonderful stay for a small bachelorette party. Had a wonderful time!"
Kara 1-night trip
Posted 1 day ago
Ameristar Casino Resort and Spa

Frequently asked questions

Looking for a spa hotel in St. Charles?
Book one of our lush spa hotels and pamper yourself from the moment you arrive. Travelers highly recommend the restaurants in St. Charles. Enjoy the historical sites and riverfront during your vacation. Hotels with spas are a great way to break away from your daily routine and add a layer of luxury to your vacation.
What is the best spa hotel in St. Charles?
Ameristar Casino Resort and Spa is a top luxury spa hotel featuring 6 restaurants, a casino, a 24-hour fitness center, and an outdoor pool. Treat yourself to a facial, body scrub, or hydrotherapy at Ara.
How many spa hotels will I find in St. Charles?
Among Expedia's 178 accommodation options in St. Charles, there is 1 spa hotel.
What's there to see and do in St. Charles?
Experience all that St. Charles has to offer when you visit Historic Main Street, Katy Trail, and Lewis & Clark Boathouse and Nature Center. If you have some spare time during your trip, you might want to check out St Charles Convention Center and Ameristar Casino St. Charles.
What is a St. Charles spa hotel?
Spa hotels in St. Charles provide lodging and have an on-site spa which offers services like couples massages as well as body treatments. Some also offer in-room treatments. Spa hotels are a must if you want to give yourself an extra treat while on vacation.

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