Find Business Hotels in Southern Illinois, IL

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Check availability on Southern Illinois Business Hotels

Tonight
Feb 1 - Feb 2
Tomorrow
Feb 2 - Feb 3
Next weekend
Feb 6 - Feb 8
In two weeks
Feb 13 - Feb 15

Our top choices for Southern Illinois business-friendly hotels

Exterior

Holiday Inn Express & Suites Mount Vernon by IHG

Holiday Inn Express & Suites Mount Vernon by IHG
2.5 star property
Mount Vernon
9.0 out of 10, Wonderful, (1,001 reviews)
"Breakfast very good staff excellent room clean and comfortable "
United States
Scott
The price is NT$3,367
NT$3,799 total
includes taxes & fees
Feb 6 - Feb 7
Holiday Inn Express & Suites Mount Vernon by IHG
Lobby

Comfort Suites Mount Vernon

Comfort Suites Mount Vernon
2.5 star property
Mount Vernon
9.0 out of 10, Wonderful, (1,006 reviews)
"Staff was so nice room clean"
United States
Helen
The price is NT$3,419
NT$3,858 total
includes taxes & fees
Feb 3 - Feb 4
Comfort Suites Mount Vernon
Lobby lounge

Drury Plaza Hotel Mt. Vernon

Drury Plaza Hotel Mt. Vernon
3.0 star property
Mount Vernon
9.6 out of 10, Exceptional, (1,644 reviews)
"Hotel is very clean, nicely furnished and the beds were so comfy!"
United States
Christina
The price is NT$3,492
NT$3,939 total
includes taxes & fees
Feb 6 - Feb 7
Drury Plaza Hotel Mt. Vernon
Front of property - evening/night

Country Inn & Suites by Radisson, Effingham, IL

Country Inn & Suites by Radisson, Effingham, IL
2.5 star property
Effingham
8.8 out of 10, Excellent, (1,001 reviews)
"Clean, friendly staff and good breakfast. Location is excellent. "
United States
Maria
The price is NT$2,808
NT$3,117 total
includes taxes & fees
Feb 22 - Feb 23
Country Inn & Suites by Radisson, Effingham, IL
Desk, laptop workspace, blackout drapes, iron/ironing board

Baymont by Wyndham Effingham

Baymont by Wyndham Effingham
2.5 star property
Effingham
8.0 out of 10, Very Good, (1,001 reviews)
"The hotel location was good, the room was clean, and the staff was kind."
United States
JoAnn
The price is NT$2,265
NT$2,514 total
includes taxes & fees
Feb 6 - Feb 7
Baymont by Wyndham Effingham
Exterior

La Quinta Inn & Suites by Wyndham Effingham

La Quinta Inn & Suites by Wyndham Effingham
3.0 star property
Effingham
9.2 out of 10, Wonderful, (1,001 reviews)
"Staff was amazing and the brekfast was good too!"
United States
Kevin
The price is NT$2,942
NT$3,294 total
includes taxes & fees
Feb 22 - Feb 23
La Quinta Inn & Suites by Wyndham Effingham
Lobby

Drury Inn & Suites Marion

Drury Inn & Suites Marion
3.0 star property
Marion
9.4 out of 10, Exceptional, (1,000 reviews)
"Clean rooms, great food, friendly staff"
United States
John
The price is NT$2,957
NT$3,548 total
includes taxes & fees
Feb 8 - Feb 9
Drury Inn & Suites Marion
Lobby

SureStay Hotel by Best Western Whittington Rend Lake

SureStay Hotel by Best Western Whittington Rend Lake
2.5 star property
Whittington
8.8 out of 10, Excellent, (928 reviews)
"Great place to stay."
United States
Stephen
The price is NT$2,265
NT$2,514 total
includes taxes & fees
Feb 8 - Feb 9
SureStay Hotel by Best Western Whittington Rend Lake
Exterior

Holiday Inn Effingham by IHG

Holiday Inn Effingham by IHG
3.5 star property
Effingham
9.0 out of 10, Wonderful, (661 reviews)
"Nice place with bar and restaurant on site."
United States
Steve
The price is NT$3,430
NT$3,841 total
includes taxes & fees
Feb 22 - Feb 23
Holiday Inn Effingham by IHG
Lobby

Ramada by Wyndham Vandalia

Ramada by Wyndham Vandalia
2.0 star property
Vandalia
7.8 out of 10, Good, (817 reviews)
"The room was clean, the staff was friendly, respectful and very helpful "
United States
Dianna
The price is NT$2,140
NT$2,332 total
includes taxes & fees
Feb 2 - Feb 3
Ramada by Wyndham Vandalia
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties

Top Southern Illinois Hotel Reviews

Comfort Suites Mount Vernon

Comfort Suites Mount Vernon

10/10 Excellent
"Great staff "
Nicole 1-night trip
Posted 2 days ago
Comfort Suites Mount Vernon

Frequently asked questions

How much do business-friendly hotels in Southern Illinois cost?
You'll pay between NT$2,332 and NT$3,939 per night for business-friendly hotels in Southern Illinois. Awesome deals on properties that cater to work-related travelers are a few clicks away on Expedia. These prices were available on Expedia within the past 7 days, for a hotel booking with a check-in date within the next year. Prices reflect current offers and availability is subject to change. Additional terms may apply.
What are the best business-friendly hotels in Southern Illinois?
That depends on your destination in Southern Illinois. Many business travelers to O'Fallon like to base themselves at Drury Inn & Suites St. Louis O'Fallon, IL. This 3-stars property comes with a swimming pool and complimentary breakfast. Hampton Inn O'Fallon is another top option if you're attending a conference or working remotely in O'Fallon. A swimming pool and an electric car charging station are among the handy amenities at this 2.5-stars getaway. When work takes you on the road, you can choose from multiple business-friendly hotels in Southern Illinois that have a total average guest review rating of 8.8.
How many business-friendly hotels are there in Southern Illinois?
Pick from 149 business-friendly hotels in Southern Illinois. Wherever your job is taking you, Expedia makes it a breeze to find the ideal space with the amenities you want.
What are the best cheap business-friendly hotels in Southern Illinois?
Keep costs low with Expedia's business-friendly hotels in Southern Illinois that start at NT$2,332 per night. A cheaper property in O'Fallon is Hampton Inn O'Fallon. Corporate guests rate it highly for its many amenities, including an electric car charging station and a swimming pool. If you're basing yourself in Effingham, choose Holiday Inn Express And Suites Effingham, an IHG Hotel. A swimming pool and a garden are among the conveniences provided for both business and leisure travelers. You'll find loads of free and interesting things to do wherever you go in Southern Illinois. If you have a meeting or conference in O'Fallon, try to find time to visit St. Clair Bowl. You can also go sightseeing for a song in Effingham. Mid America Motorworks, My Garage Museum is one of the best free attractions here. This price was available on Expedia within the past 7 days, for a hotel booking with a check-in date within the next year. Prices reflect current offers and availability is subject to change. Additional terms may apply.
Are there any family-friendly hotels in Southern Illinois that are also business friendly?
You'll discover some terrific family-friendly hotels that are also business friendly in Southern Illinois. If you're traveling to O'Fallon, look up Drury Inn & Suites St. Louis O'Fallon, IL. It offers handy amenities such as complimentary breakfast and a laundry service and has a 3-stars rating. Another property worth considering is Drury Inn & Suites St. Louis Fairview Heights. This 3-stars stay in O'Fallon is ideal for both leisure and business travelers and offers complimentary breakfast, a laundry service and much more. Once you've gotten work out of the way, get out and discover O'Fallon with the kids. Favorite family-friendly attractions include The Edge and St. Clair Bowl.
Why book your business-friendly hotel in Southern Illinois with Expedia?
At Expedia, we make it our job to help you locate an amazing stay at the right price. From luxurious, corporate-friendly properties to affordable hotels filled with handy amenities, you'll have your next work trip booked in a few easy clicks.
How can I find cheap business-friendly hotels in Southern Illinois?
When you're traveling for work in Southern Illinois, our "business friendly" filter will help you find the ideal hotel. From free WiFi to workspaces and meeting rooms, they have the amenities you need to be productive. Another useful tip? Refine your search by your budget and preferred star rating to view the most affordable options.
What is there to do in Southern Illinois near my business-friendly hotel?
Southern Illinois has so much to see and do, it can be tricky to figure out where to start. If you're spending a few nights in O'Fallon, The Edge is a much-loved attraction here.

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