Find Business Hotels in Southern Illinois, IL

Start date: Check-in selected.
To Date
End date: Check-out

    Change your mind

    Book hotels with free cancellation

    Treat yourself

    Sign in to save 10% or more on thousands of hotels
    Sign in

    Be picky

    Search almost a million properties worldwide

Check availability on Southern Illinois Business Hotels

Top Southern Illinois Business Hotels

Exterior
Holiday Inn Express & Suites Effingham by IHG
Holiday Inn Express & Suites Effingham by IHG
2.5 star property
9.4 out of 10, Exceptional, (1001)
"Was a very nice stay and convenient to interstate"
The price is NT$3,154
NT$3,531 total
includes taxes & fees
Oct 19 - Oct 20
Holiday Inn Express & Suites Effingham by IHG
Exterior
Drury Inn & Suites Marion
Drury Inn & Suites Marion
3.0 star property
9.4 out of 10, Exceptional, (1006)
"Great hotel and very clean "
The price is NT$1,986
NT$2,383 total
includes taxes & fees
Nov 2 - Nov 3
Drury Inn & Suites Marion
Free daily buffet breakfast
Holiday Inn Express Hotel & Suites Marion Northeast by IHG
Holiday Inn Express Hotel & Suites Marion Northeast by IHG
2.5 star property
9.0 out of 10, Wonderful, (914)
"Clean room, friendly staff, gym and pool"
The price is NT$3,031
NT$3,637 total
includes taxes & fees
Nov 1 - Nov 2
Holiday Inn Express Hotel & Suites Marion Northeast by IHG
Free daily buffet breakfast
Holiday Inn Express & Suites Mount Vernon by IHG
Holiday Inn Express & Suites Mount Vernon by IHG
2.5 star property
9.0 out of 10, Wonderful, (1012)
"Great stay"
The price is NT$2,909
NT$3,290 total
includes taxes & fees
Nov 2 - Nov 3
Holiday Inn Express & Suites Mount Vernon by IHG
Exterior
Holiday Inn Carbondale-Conference Center by IHG
Holiday Inn Carbondale-Conference Center by IHG
3.0 star property
8.8 out of 10, Excellent, (613)
"Nice staff, clean rooms, awesome beds and pillows!"
The price is NT$2,787
NT$3,204 total
includes taxes & fees
Nov 9 - Nov 10
Holiday Inn Carbondale-Conference Center by IHG
Lobby
Drury Plaza Hotel Mt. Vernon
Drury Plaza Hotel Mt. Vernon
3.0 star property
9.6 out of 10, Exceptional, (1493)
"Excellent hotel! Clean, excellent breakfast, and friendly staff!"
The price is NT$2,872
NT$3,249 total
includes taxes & fees
Oct 31 - Nov 1
Drury Plaza Hotel Mt. Vernon
Room, 2 Queen Beds, Non Smoking | Desk, soundproofing, iron/ironing board, rollaway beds
Country Inn & Suites by Radisson, Effingham, IL
Country Inn & Suites by Radisson, Effingham, IL
2.5 star property
8.8 out of 10, Excellent, (1006)
"We had a very nice stay."
The price is NT$2,907
NT$3,226 total
includes taxes & fees
Nov 9 - Nov 10
Country Inn & Suites by Radisson, Effingham, IL
Free daily self-serve breakfast
Holiday Inn Express & Suites Murphysboro - Carbondale by IHG
Holiday Inn Express & Suites Murphysboro - Carbondale by IHG
2.5 star property
9.4 out of 10, Exceptional, (489)
"great property, great breakfast, friendly and knowledgable staff."
The price is NT$3,178
NT$3,527 total
includes taxes & fees
Nov 9 - Nov 10
Holiday Inn Express & Suites Murphysboro - Carbondale by IHG
Free daily continental breakfast
Best Western Delta Inn
Best Western Delta Inn
2.5 star property
9.2 out of 10, Wonderful, (1022)
"Easy parking and great breakfast "
The price is NT$2,720
NT$3,046 total
includes taxes & fees
Oct 19 - Oct 20
Best Western Delta Inn
Lobby
SureStay Hotel by Best Western Whittington Rend Lake
SureStay Hotel by Best Western Whittington Rend Lake
2.5 star property
8.8 out of 10, Excellent, (874)
"Great place to stay."
The price is NT$2,200
NT$2,441 total
includes taxes & fees
Oct 23 - Oct 24
SureStay Hotel by Best Western Whittington Rend Lake
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties

Top Southern Illinois Hotel Reviews

Best Western Plus Pontoon Beach

Best Western Plus Pontoon Beach

10/10 Excellent
"Very quiet and clean"
Randall 1-night trip
Posted 16 hours ago
Best Western Plus Pontoon Beach

Explore a world of travel with Expedia

Frequently asked questions

How much do business-friendly hotels in Southern Illinois cost?
You'll pay between and per night for business-friendly hotels in Southern Illinois. Awesome deals on properties that cater to work-related travelers are a few clicks away on Expedia. These prices were available on Expedia within the past 7 days, for a hotel booking with a check-in date within the next year. Prices reflect current offers and availability is subject to change. Additional terms may apply.
What are the best business-friendly hotels in Southern Illinois?
That depends on your destination in Southern Illinois. Many business travelers to O'Fallon like to base themselves at Drury Inn & Suites St. Louis O'Fallon, IL. This 3-stars property comes with a swimming pool and complimentary breakfast. Hampton Inn O'Fallon is another top option if you're attending a conference or working remotely in O'Fallon. A swimming pool and an electric car charging station are among the handy amenities at this 2.5-stars getaway. When work takes you on the road, you can choose from multiple business-friendly hotels in Southern Illinois that have a total average guest review rating of .
How many business-friendly hotels are there in Southern Illinois?
Pick from business-friendly hotels in Southern Illinois. Wherever your job is taking you, Expedia makes it a breeze to find the ideal space with the amenities you want.
What are the best cheap business-friendly hotels in Southern Illinois?
Keep costs low with Expedia's business-friendly hotels in Southern Illinois that start at per night. A cheaper property in O'Fallon is Hampton Inn O'Fallon. Corporate guests rate it highly for its many amenities, including an electric car charging station and a swimming pool. If you're basing yourself in Effingham, choose Holiday Inn Express And Suites Effingham, an IHG Hotel. A swimming pool and a garden are among the conveniences provided for both business and leisure travelers. You'll find loads of free and interesting things to do wherever you go in Southern Illinois. If you have a meeting or conference in O'Fallon, try to find time to visit St. Clair Bowl. You can also go sightseeing for a song in Effingham. Mid America Motorworks, My Garage Museum is one of the best free attractions here. This price was available on Expedia within the past 7 days, for a hotel booking with a check-in date within the next year. Prices reflect current offers and availability is subject to change. Additional terms may apply.
Are there any family-friendly hotels in Southern Illinois that are also business friendly?
You'll discover some terrific family-friendly hotels that are also business friendly in Southern Illinois. If you're traveling to O'Fallon, look up Drury Inn & Suites St. Louis O'Fallon, IL. It offers handy amenities such as complimentary breakfast and a laundry service and has a 3-stars rating. Another property worth considering is Drury Inn & Suites St. Louis Fairview Heights. This 3-stars stay in O'Fallon is ideal for both leisure and business travelers and offers complimentary breakfast, a laundry service and much more. Once you've gotten work out of the way, get out and discover O'Fallon with the kids. Favorite family-friendly attractions include The Edge and St. Clair Bowl.
Why book your business-friendly hotel in Southern Illinois with Expedia?
At Expedia, we make it our job to help you locate an amazing stay at the right price. From luxurious, corporate-friendly properties to affordable hotels filled with handy amenities, you'll have your next work trip booked in a few easy clicks.
How can I find cheap business-friendly hotels in Southern Illinois?
When you're traveling for work in Southern Illinois, our "business friendly" filter will help you find the ideal hotel. From free WiFi to workspaces and meeting rooms, they have the amenities you need to be productive. Another useful tip? Refine your search by your budget and preferred star rating to view the most affordable options.
What is there to do in Southern Illinois near my business-friendly hotel?
Southern Illinois has so much to see and do, it can be tricky to figure out where to start. If you're spending a few nights in O'Fallon, The Edge is a much-loved attraction here.