Santa Cruz
Seville
Visit Santa Cruz
Popular places to visit
Royal Alcázar of Seville
Discover a millennium’s worth of royal treasures in this architectural masterpiece in the heart of Seville.
Giralda Tower
Once among the tallest religious monuments in the world, this former minaret is now the eye-catching bell tower to Seville Cathedral.
San Telmo Palace
Tour the striking interior and exterior of a palatial building that serves as the headquarters of the president of the autonomous region of Andalusia.
Cabildo Catedral
Stop by a 16th-century meeting room inside the Cathedral of Seville that is stunningly decorated with religious paintings, sculptures and reliefs.
Triunfo Plaza
From this ancient and picturesque square, access some of the oldest and most impressive buildings in Seville, including the world’s largest gothic cathedral.
Seville Cathedral
See Columbus’ tomb, artwork by Goya and Murillo and plenty of breathtaking architecture all within the largest Gothic cathedral in Europe.
Santa Cruz Hotel Deals
Hotel Murillo
"I loved this hotel. Located in the middle of everything."
Reviewed on 2026/5/25
Las Casas de la Judería, Sevilla Historic City Center
"Great & fascinating hotel in a good location. Loved it."
Reviewed on 2026/5/25
Hotel Amadeus Sevilla
"Wonderfull Staff that speaks Spanish and English, a beautiful rooftop bar/lounge area with pool and hot tub, and lots of gorgeous common sitting spaces to relay, read, work, etc."
Reviewed on 2026/5/25
Hotel Alfonso XIII, a Luxury Collection Hotel, Seville
"The breakfast bar offered a nice selection of foods. For dinner, I had the best Flan I’ve ever eaten"
Reviewed on 2026/5/17
Hotel Rey Alfonso X
"The hotel was spotless, had lovely amenities ie rooftop terrace was stunning and the young waitress at the bar was always happy and helpful. The breakfast had an excellent selection of fresh food and the waiting staff were always polite, friendly and accommodating. I’d highly recommend anyone to ..."
Reviewed on 2026/5/22
Hotel Murillo Reinoso
"Un lugar muy bonito. Relajado."
Reviewed on 2026/5/26
Other neighborhoods around Santa Cruz
El Arenal
Located in Seville's historical center, El Arenal boasts the 13th-century Torre del Oro, Royal Shipyards, and La Real Maestranza bullring. Explore this vibrant area on the Guadalquivir river's east bank.
San Bartolomé
Travelers come to San Bartolomé for its lively bars, and you can see top attractions like Pilate's House and Zurbarán Statue while you're in town.
Alfalfa
Unique features of Alfalfa include the bars and historic sites. Make a stop by Salvador Plaza or Calle Sierpes while you're exploring the area.
Historical Center
Casa de la Memoria Cultural Center and Calle Sierpes are a few top attractions in Historical Center. Hop around the city on the metro at Plaza Nueva Tram Stop or Archivo de Indias Tram Stop and check out the area's fantastic nightlife, stunning cathedral, and popular shops.
La Florida
The restaurants and shopping are a few reasons travelers visit La Florida. Want to see more of the surrounding area? Murillo Gardens and Pilate's House are a few top sights nearby.
San Bernardo
Even though there aren't top sights in San Bernardo, you can explore the larger area and take in top sights like Murillo Gardens. Jump on the metro at Prado San Sebastián Tram Stop to see more of the city.
