Find Family Hotels in Seneca, SC

Start date: Check-in selected.
To Date
End date: Check-out
  • Change your mind

    Book hotels with free cancellation
  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
  • Be picky

    Search almost a million properties worldwide

Check availability on Seneca Family Hotels

Next weekend
In two weeks

Our top choices for Seneca family-friendly hotels

Fairfield Inn & Suites Seneca Clemson Univ Area

Fairfield Inn & Suites Seneca Clemson Univ Area
2.5 star property
Seneca
9.4 out of 10, Exceptional, (204)
"Nice hotel by the lake"
United States
Mike
The price is NT$3,630
NT$3,993 total
includes taxes & fees
Dec 28 - Dec 29
Fairfield Inn & Suites Seneca Clemson Univ Area

Quality Inn & Suites Easley - Greenville

Quality Inn & Suites Easley - Greenville
2.5 star property
Easley
7.0 out of 10, Good, (387)
"Staff was very friendly and accommodating "
United States
Lisa
The price is NT$1,641
NT$1,822 total
includes taxes & fees
Dec 28 - Dec 29
Quality Inn & Suites Easley - Greenville

Baymont by Wyndham Anderson Clemson

Baymont by Wyndham Anderson Clemson
2.5 star property
Anderson
7.0 out of 10, Good, (844)
"Well lit parking and safe area around the hotel"
United States
Gregory
The price is NT$1,878
NT$2,084 total
includes taxes & fees
Jan 12 - 2026/1/13
Baymont by Wyndham Anderson Clemson

Holiday Inn Express Hotel & Suites Anderson-I-85 by IHG

Holiday Inn Express Hotel & Suites Anderson-I-85 by IHG
2.5 star property
Anderson
9.0 out of 10, Wonderful, (582)
"It was great. Room was clean and staff was friendly. "
United States
Veronica
The price is NT$3,251
NT$3,608 total
includes taxes & fees
Dec 24 - Dec 25
Holiday Inn Express Hotel & Suites Anderson-I-85 by IHG

Rodeway Inn Anderson North - Clemson

Rodeway Inn Anderson North - Clemson
2.0 star property
Anderson
7.8 out of 10, Good, (316)
"Nice beds"
United States
Tammy
The price is NT$2,052
NT$2,277 total
includes taxes & fees
Dec 23 - Dec 24
Rodeway Inn Anderson North - Clemson
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Top Seneca Hotel Reviews

Frequently asked questions

What's Seneca like for family-friendly vacations?
The welcoming destination of Seneca is a good choice if you've been considering a getaway with your kids. The boating, lake views, and sporting events are just some of the things that make this the perfect spot for family trips. Fly into Greenville-Spartanburg Intl. Airport (GSP), which is located 44.1 mi (71 km) from the city center.
What's the best accommodation for families in Seneca?
Fairfield Inn & Suites Seneca Clemson Univ Area is a hotel with an outdoor pool and free parking, and it's a top choice on Expedia for families.
When's the best time to book a family-friendly vacation in Seneca?
The hottest months are usually July and August with an average temp of 76°F, while the coldest months are January and February with an average of 46°F. Average annual precipitation for Seneca is 62 inches.
What's there to see and do with your family in Seneca?
While you and your family are vacationing in Seneca, you might want to visit some family-friendly attractions such as The Gauntlet and Oconee County Library Seneca Branch. Make sure you have lots of time for activities like Bertha Lee Strickland Cultural Museum and Golden Corner Plaza.

Explore a world of travel with Expedia