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Dec 23 - Dec 24
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Dec 24 - Dec 25
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Our top choices for Santiago hotels

Courtyard
Living Up

Living Up

Living Up
3.0 star property
Santiago
8.0 out of 10, Very Good, (1)
"La habitación estuvo muy bonita y la atención del personal dentro de las instalaciones muy gentil y servicial."
Mexico
Daniel
The price is NT$1,342
NT$1,859 total
includes taxes & fees
Dec 26 - Dec 27
Living Up
Apartment | Exterior
Loft Carrara

Loft Carrara

Loft Carrara
2.0 star property
18.4 km from Santiago
10.0 out of 10, Exceptional, (6)
"Muy bonito el lugar y limpio"
Mexico
Rosa
The price is NT$7,267
NT$9,189 total
includes taxes & fees
Jan 11 - 2026/1/12
Loft Carrara
Elite Suite (Camaldoni) | Premium bedding, pillowtop beds, in-room safe, individually decorated
Villa Toscana ValQuirico Lofts & Suites Hotel Boutique

Villa Toscana ValQuirico Lofts & Suites Hotel Boutique

Villa Toscana ValQuirico Lofts & Suites Hotel Boutique
3.5 star property
18.3 km from Santiago
9.6 out of 10, Exceptional, (366)
"The rooms were very nice, though the area is made to look like Italian towns tbe rooms were large and confortable highly recommend a stay at this hotel "
United States
Jose
The price is NT$4,574
NT$5,398 total
includes taxes & fees
Jan 22 - 2026/1/23
Villa Toscana ValQuirico Lofts & Suites Hotel Boutique
Reception
Hotel Teresita

Hotel Teresita

Hotel Teresita
2.5 star property
Puebla Historic Center, 1.2 km from Santiago
8.4 out of 10, Very Good, (302)
"A bit hot in the rooms and voices carry in the lobby. Overall a great stay."
United States
Marlene
Hotel Teresita
Reception
Hotel Las Iglesias, Cholula

Hotel Las Iglesias, Cholula

Hotel Las Iglesias, Cholula
3.0 star property
10.7 km from Santiago
8.8 out of 10, Excellent, (556)
"The room was excellent and the staff were very friendly and helpful. We truly loved this hotel. "
United States
Rogelio
Hotel Las Iglesias, Cholula
Front of property
Posada Guadalupe

Posada Guadalupe

Posada Guadalupe
2.0 star property
Puebla Historic Center, 1.3 km from Santiago
8.6 out of 10, Excellent, (314)
"Great Hotel location, just Puebla downtown. Will stay again. "
United States
Sergio
Posada Guadalupe
Indoor pool
Fiesta Inn Express Puebla Explanada

Fiesta Inn Express Puebla Explanada

Fiesta Inn Express Puebla Explanada
3.0 star property
7.5 km from Santiago
9.4 out of 10, Exceptional, (997)
"Great location"
United States
Epifania
The price is NT$1,968
NT$2,342 total
includes taxes & fees
Jan 3 - 2026/1/4
Fiesta Inn Express Puebla Explanada
Interior entrance
Hotel Aroma 406

Hotel Aroma 406

Hotel Aroma 406
2.5 star property
Puebla Historic Center, 1.7 km from Santiago
8.6 out of 10, Excellent, (148)
"Clean room"
United States
Severiano
Hotel Aroma 406
Porch
Comfort Inn Puebla Centro Histórico

Comfort Inn Puebla Centro Histórico

Comfort Inn Puebla Centro Histórico
3.0 star property
Puebla Historic Center, 0.5 km from Santiago
9.0 out of 10, Wonderful, (1002)
"Great Staff"
United States
Susana
The price is NT$1,974
NT$2,349 total
includes taxes & fees
Jan 5 - 2026/1/6
Comfort Inn Puebla Centro Histórico
Exterior
La Quinta Puebla

La Quinta Puebla

La Quinta Puebla
3.0 star property
7.1 km from Santiago
7.8 out of 10, Good, (236)
"Wi-fi connection is not always stable but staff was good"
United States
Juan
The price is NT$796
NT$947 total
includes taxes & fees
Dec 26 - Dec 27
La Quinta Puebla
In-room safe, desk, free WiFi, bed sheets
Hotel Marques Del Angel

Hotel Marques Del Angel

Hotel Marques Del Angel
4.0 star property
Puebla Historic Center, 1.1 km from Santiago
9.4 out of 10, Exceptional, (280)
"Excellent service "
United States
Mayra
Hotel Marques Del Angel
Terrace/patio
Hotel Diana

Hotel Diana

Hotel Diana
3.5 star property
Puebla Historic Center, 1.1 km from Santiago
9.0 out of 10, Wonderful, (689)
"Excelente "
Mexico
Fernando
Hotel Diana
Flat-screen TV
HOTEL SANTIAGO

HOTEL SANTIAGO

HOTEL SANTIAGO
2.5 star property
Puebla Historic Center, 1.4 km from Santiago
9.2 out of 10, Wonderful, (161)
"H Santiago is located 1/2 block from the Zocalo and Cathedral. Plenty of shopping options and affordable eateries - some of the restaurants in this area are pricey. Staff are attentive and certainly keep the areas and room clean."
United States
Jose
HOTEL SANTIAGO
Lobby
Sleep Inn Puebla Centro Histórico

Sleep Inn Puebla Centro Histórico

Sleep Inn Puebla Centro Histórico
3.0 star property
Puebla Historic Center, 2.1 km from Santiago
8.6 out of 10, Excellent, (886)
"Everything was great except for the pillows they were too flat. The room was large in spacious. The food was great."
United States
Mary
The price is NT$1,680
NT$2,000 total
includes taxes & fees
Jan 4 - 2026/1/5
Sleep Inn Puebla Centro Histórico
Minibar, in-room safe, desk, soundproofing
NH Puebla Finsa

NH Puebla Finsa

NH Puebla Finsa
3.5 star property
6.7 km from Santiago
9.2 out of 10, Wonderful, (376)
"good place to stay on a budget."
Mexico
Josué Elías Pérez
The price is NT$1,474
NT$1,754 total
includes taxes & fees
Jan 11 - 2026/1/12
NH Puebla Finsa
Garden
Hotel Panamerican

Hotel Panamerican

Hotel Panamerican
3.0 star property
1 km from Santiago
8.4 out of 10, Very Good, (921)
"It was super nice, the staff were very attentive and polite, and the place was very clean and tidy. It also has many amenities. We would definitely go back!"
Canada
Kevin
The price is NT$1,387
NT$1,650 total
includes taxes & fees
Dec 24 - Dec 25
Hotel Panamerican
Gazebo
Casona María

Casona María

Casona María
4.0 star property
Barrio De Analco, 2.4 km from Santiago
9.4 out of 10, Exceptional, (451)
"I made a mistake in selecting Casona Maria for my visit to Puebla. It's a mistake I won't make again."
United States
Jerold
The price is NT$4,713
NT$5,608 total
includes taxes & fees
Dec 24 - Dec 25
Casona María
Deluxe Room, 1 King Bed | Premium bedding, desk, iron/ironing board, free WiFi
HOTEL MARGARITA

HOTEL MARGARITA

HOTEL MARGARITA
3.0 star property
Puebla Historic Center, 0.7 km from Santiago
9.2 out of 10, Wonderful, (82)
"We liked the decorations and the structure. The personel at the front desk is polite and very attentive."
United States
ROBERTO
HOTEL MARGARITA
Double Room | In-room safe, desk, free WiFi, bed sheets
Hotel Sofia

Hotel Sofia

Hotel Sofia
2.5 star property
Puebla Historic Center, 1.1 km from Santiago
8.2 out of 10, Very Good, (542)
"Excelente"
Mexico
Dante
The price is NT$1,005
NT$1,197 total
includes taxes & fees
Jan 11 - 2026/1/12
Hotel Sofia
Bar (on property)
Hotel Isabel

Hotel Isabel

Hotel Isabel
3.0 star property
Puebla Historic Center, 1.2 km from Santiago
9.0 out of 10, Wonderful, (1004)
"Love the closeness to everything and food options around the area. Staff was very attentive to mine and my elderly mothers needs. Will definitely be back"
United States
Juan
The price is NT$1,527
NT$1,818 total
includes taxes & fees
Jan 3 - 2026/1/4
Hotel Isabel
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties

Where to stay in Santiago

Find the best Santiago areas and neighborhoods for the activities you enjoy most.
Zocalo Square featuring heritage elements

Puebla Historic Center

Discover a World Heritage Site filled with colonial buildings in the Historic Monuments Zone, where you can explore Barrio de los Sapos, Barrio del Artista, and the stunning Puebla Cathedral.

Angelópolis

The neighborhood boasts luxurious residential developments, cultural spaces, and parks. Explore attractions like La Estrella de Puebla, The Art Park, and the Baroque Museum, or shop at Centro Comercial Angelópolis.

La Virgen de los Remedios Sanctuary showing heritage elements and mountains

Cholula

Best known for its Great Pyramid and numerous churches, Cholula features the Iglesia de Nuestra Señora de los Remedios sanctuary atop the pyramid. Explore the city's eighteen distinct barrios, each with a patron saint.

Cholula Centro

While visiting Cholula Centro, you might make a stop by sights like San Gabriel Convent and Plaza de la Concordia.

La Paz

While La Paz isn't home to many top sights, Galerías Serdán and Triangulo Las Animas Shopping Center are some notable places to visit nearby.

Top Santiago Hotel Reviews

Cartesiano Boutique & Wellness Hotel

Cartesiano Boutique & Wellness Hotel

10/10 Excellent
"We had a fantastic time. The staff were very helpful and nice. Gabriela gave us some good education on Mezcal and Tequila. "
Kevin 3-night trip
Posted 3 days ago
Cartesiano Boutique & Wellness Hotel

Frequently asked questions

What's it like in Santiago?
You'll be sure to have fun visiting Puebla's Santiago neighborhood.
If I need to cancel my hotel reservation in Santiago, will I receive a refund?
Yes, the majority of hotel room reservations are fully refundable if cancelled before the accommodation's cancellation deadline, which in most cases is within 24 or 48 hours of your scheduled arrival. If you have a non-refundable reservation, you might be able to still cancel and get a refund within 24 hours of your booking. Enter dates in and click on "Search", then you can filter by "fully refundable" to get the best options available in Santiago.
Where can I learn more about changing or cancelling my trip to Santiago?
For more information about updating your trip to Santiago or cancelling it, go to https://www.expedia.com/service/.
What is there to do in this Puebla neighborhood?
Plaza de Revolución, Museum of the Mexican Army and Air Force, and Uriarte Talavera are just a few of the places to visit in and around Santiago. Profetica and Bello Museum are also worth a visit when you're out sightseeing in Puebla.

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