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Our top choices for Santa Clara hotels

Riande Aeropuerto Hotel & Casino

Riande Aeropuerto Hotel & Casino
4.0 star property
Tocumen
8.4 out of 10, Very Good, (1,859 reviews)
"Very nice staff and confortable stay"
United States
MARIA
The price is NT$3,930
NT$4,323 total
includes taxes & fees
Mar 1 - Mar 2
Riande Aeropuerto Hotel & Casino

The Santa Maria, A Luxury Collection Hotel & Golf Resort, Panama City

The Santa Maria, A Luxury Collection Hotel & Golf Resort, Panama City
5.0 star property
Juan Diaz
9.6 out of 10, Exceptional, (666 reviews)
"As usual the stay was amazing in this hotel"
United States
Jose
The price is NT$8,564
NT$9,420 total
includes taxes & fees
Mar 27 - Mar 28
The Santa Maria, A Luxury Collection Hotel & Golf Resort, Panama City

Arcadia Condo Suites

Arcadia Condo Suites
2.5 star property
Costa del Este
9.4 out of 10, Exceptional, (220 reviews)
"Really loved this place"
United States
Alejandra
The price is NT$2,619
NT$4,342 total
includes taxes & fees
Mar 2 - Mar 3
Arcadia Condo Suites

Courtyard by Marriott Panama Metromall

Courtyard by Marriott Panama Metromall
4.0 star property
San Antonio
8.8 out of 10, Excellent, (1,008 reviews)
"Staff was good rooms clean just a good experience "
United States
Adrian
The price is NT$3,313
NT$3,644 total
includes taxes & fees
Mar 23 - Mar 24
Courtyard by Marriott Panama Metromall

MARINN Tropical Vibes Hotel

MARINN Tropical Vibes Hotel
3.5 star property
Amador
8.2 out of 10, Very Good, (230 reviews)
"Great rooms, pleasant staff, lovely location, lots of eats and drinks options"
United States
Rajiv Sachin
The price is NT$2,793
NT$3,073 total
includes taxes & fees
Feb 27 - Feb 28
MARINN Tropical Vibes Hotel

Hotel Riu Plaza Panama

Hotel Riu Plaza Panama
5.0 star property
Bella Vista
9.0 out of 10, Wonderful, (5,022 reviews)
"Great pool and restaurant."
Canada
Terri
The price is NT$3,817
NT$4,199 total
includes taxes & fees
Mar 8 - Mar 9
Hotel Riu Plaza Panama

The Westin Panama

The Westin Panama
4.0 star property
Costa del Este
9.0 out of 10, Wonderful, (319 reviews)
"Great hotel and services"
United States
Pedro
The price is NT$7,045
NT$7,750 total
includes taxes & fees
Mar 27 - Mar 28
The Westin Panama

Plaza Paitilla Inn Hotel

Plaza Paitilla Inn Hotel
3.5 star property
San Francisco
9.4 out of 10, Exceptional, (2,153 reviews)
"Hotel was very clean, the staff was very helpful and the breakfast was very good!"
United States
Monty
The price is NT$3,414
NT$3,756 total
includes taxes & fees
Mar 26 - Mar 27
Plaza Paitilla Inn Hotel

Ramada Plaza by Wyndham Panama Punta Pacifica

Ramada Plaza by Wyndham Panama Punta Pacifica
4.0 star property
San Francisco
9.6 out of 10, Exceptional, (1,164 reviews)
"Clean, nice staff and super close to the airport "
United States
Leticia
The price is NT$2,989
NT$3,288 total
includes taxes & fees
Mar 4 - Mar 5
Ramada Plaza by Wyndham Panama Punta Pacifica

Albrook Inn

Albrook Inn
3.0 star property
Panama City
7.8 out of 10, Good, (582 reviews)
"Friendly front desk staff, comfortable bed, close proximity to airport"
United States
Hildi
The price is NT$2,057
NT$2,263 total
includes taxes & fees
Feb 25 - Feb 26
Albrook Inn

The Beach House

The Beach House
3.0 star property
Amador
8.4 out of 10, Very Good, (417 reviews)
"We loved the staff, room & view! "
United States
Jerome
The Beach House

Hotel Costa Inn

Hotel Costa Inn
3.0 star property
Calidonia
7.0 out of 10, Good, (561 reviews)
"Nice bathroom "
United States
Derrick
Hotel Costa Inn

Hotel Pension Corona

Hotel Pension Corona
2.5 star property
Calidonia
7.8 out of 10, Good, (115 reviews)
"Great spot for the price "
United States
frank
Hotel Pension Corona

JW Marriott Panama

JW Marriott Panama
5.0 star property
San Francisco
9.0 out of 10, Wonderful, (1,011 reviews)
"Beautiful hotel, great service. Breakfast buffet is amazing. "
United States
Tamara
The price is NT$9,083
NT$9,991 total
includes taxes & fees
Mar 8 - Mar 9
JW Marriott Panama

Modal

Modal
2.0 star property
Panama City
10.0 out of 10, Exceptional, (1 review)
The price is NT$1,909
NT$2,100 total
includes taxes & fees
Mar 5 - Mar 6
Modal

Decapolis Hotel Panama City

Decapolis Hotel Panama City
4.0 star property
San Francisco
8.6 out of 10, Excellent, (1,571 reviews)
"Nice comfortable hotel and very friendly staff."
Canada
norah
The price is NT$3,644
NT$4,009 total
includes taxes & fees
Feb 25 - Feb 26
Decapolis Hotel Panama City

Hyatt Regency Panama City

Hyatt Regency Panama City
4.5 star property
Bella Vista
9.8 out of 10, Exceptional, (203 reviews)
"Very clean modern rooms, spacious hotel, delicious breakfast, very friendly staff!"
Canada
Sheldon
The price is NT$5,195
NT$5,715 total
includes taxes & fees
Mar 7 - Mar 8
Hyatt Regency Panama City

Sheraton Grand Panama

Sheraton Grand Panama
4.0 star property
San Francisco
8.6 out of 10, Excellent, (1,012 reviews)
"Good locatiion"
United States
Caren
The price is NT$4,241
NT$4,666 total
includes taxes & fees
Mar 8 - Mar 9
Sheraton Grand Panama

Radisson Hotel Panama Canal

Radisson Hotel Panama Canal
4.5 star property
Amador
8.6 out of 10, Excellent, (1,007 reviews)
"Unbeatable location if your visit is all about the Panama Canal. "
United States
Vitaliy
The price is NT$2,676
NT$2,943 total
includes taxes & fees
Mar 24 - Mar 25
Radisson Hotel Panama Canal

Panama House Bed & Breakfast

Panama House Bed & Breakfast
2.5 star property
Bella Vista
9.0 out of 10, Wonderful, (193 reviews)
"Amenities, staff, cleanliness, price all excellent!"
United States
Christopher
Panama House Bed & Breakfast
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Frequently asked questions

What's the best place for a stay in Santa Clara?
Located 15.8 mi (25.5 km) from the heart of Santa Clara, Hotel Riu Plaza Panama is a top choice for your stay based on our traveler data. Two other choices for your stay in the area are Hotel El Panama by Faranda Grand, a member of Radisson Individuals and Sheraton Grand Panama. See all available top hotels, or vacation rentals in Santa Clara.
If I need to cancel my hotel reservation in Santa Clara, will I receive a refund?
Yes! The majority of hotel bookings are fully refundable if cancelled before the hotel's cancellation deadline, which often is within 24-48 hours of your check-in date. If you booked a non-refundable reservation, you might be able to still cancel and get a refund within 24 hours of booking. Filter your search by fully refundable to find flexible hotel deals in Santa Clara.
Where can I learn more about changing or cancelling my trip to Santa Clara?
To access more information about rescheduling or cancelling your trip to Santa Clara, go to https://www.expedia.com/service/.
What's the best place to stay near Culebra Cut?
Gamboa Rainforest Reserve is one of the top choices for your stay based on our traveler data, and this 3.5-star hotel offers a marina and a full-service spa. It's located 2.9 mi (4.7 km) from Culebra Cut. Other good options within 5 miles include Canopy Bed & Breakfast and Casa en Gamboa al lado Canal de Panama.
What is staying in Santa Clara like?
Visitors can enjoy all that Santa Clara has to offer including its monuments. There are 1528 hotels and other accommodations in the surrounding area. Find out more about Santa Clara.
What is there to see in Santa Clara?
A favorite place to visit is Culebra Cut. You'll also find Gamboa Rainforest Resort and Miraflores Locks in the area. Check out what more to see and do in Expedia's Santa Clara guide.
What's the seasonal weather like in Santa Clara?
The hottest months are usually April and March with an average temp of 79°F, while the coldest months are January and February with an average of 78°F. The rainiest months in Santa Clara are July, August, November, and October, with each month seeing an average of 11 inches of rainfall.