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Our top choices for Panhandle Plains hotels

A hotel reception area with a wooden reception desk, a black doormat with the hotel name, and a modern interior design.

1. Fairfield Inn & Suites by Marriott Wichita Falls Northwest

Wichita Falls

Mark

NT$4,455 total

includes taxes & fees

Dec 6 - Dec 7

A modern room with a sofa, a chair, a lamp, and a television.

2. Holiday Inn Express & Suites Amarillo West by IHG

Amarillo

Marie-Pascale

NT$4,345 total

includes taxes & fees

Nov 15 - Nov 16

A multi-story hotel with a stone facade, large windows, and a covered outdoor seating area.

3. Residence Inn by Marriott Wichita Falls

Wichita Falls

Amy

NT$7,916 total

includes taxes & fees

Nov 27 - Nov 28

A La Quinta hotel with a modern design, featuring a prominent sun motif on the facade, multiple floors, and a covered entrance area.

4. La Quinta Inn & Suites by Wyndham Sweetwater East

Sweetwater

Keith

NT$6,914 total

includes taxes & fees

Nov 21 - Nov 22

A multi-story hotel with a modern design, featuring a prominent entrance with glass doors and a covered area.

5. Best Western Plus Amarillo East Hotel

Amarillo

candi

NT$4,143 total

includes taxes & fees

Nov 15 - Nov 16

An outdoor patio with a stone wall, a fire feature, and seating.

6. Hampton Inn & Suites Canyon

Canyon

Pam

NT$4,386 total

includes taxes & fees

Nov 29 - Nov 30

A modern hotel with a prominent Tru by Hilton sign, multiple parking spaces, and a well-lit entrance area.

7. Tru by Hilton Wichita Falls, TX

Wichita Falls

Mayra

NT$5,208 total

includes taxes & fees

Nov 15 - Nov 16

A spacious lobby with a grand staircase, a reception desk, and comfortable seating areas.

8. Sleep Inn & Suites Shamrock

Shamrock

Wendy

NT$4,009 total

includes taxes & fees

Nov 29 - Nov 30

A hotel entrance with a stone facade, a glass door entrance, and a tiled floor.

9. Microtel Inn & Suites by Wyndham Sweetwater

Sweetwater

barbara

NT$4,897 total

includes taxes & fees

Nov 13 - Nov 14

10. Embassy Suites by Hilton Amarillo Downtown

Downtown Amarillo

Heather

NT$5,036 total

includes taxes & fees

Nov 22 - Nov 23

A modern food service area with a central counter, a refrigerated display, and various food items.

11. Tru By Hilton Amarillo West

Amarillo

NANCY

NT$3,090 total

includes taxes & fees

Dec 8 - Dec 9

A spacious restaurant with high ceilings, stone walls, and large windows.

12. Drury Inn & Suites Amarillo

Amarillo

Jodi

NT$4,080 total

includes taxes & fees

Nov 22 - Nov 23

A room with a green sofa, two armchairs, a marble coffee table, and a large wall mural of a sunset over a rocky landscape.

13. Best Western Palo Duro Canyon Inn & Suites

Canyon

Damian

NT$4,640 total

includes taxes & fees

Nov 15 - Nov 16

A spacious lobby with a reception desk, seating area, and a patterned wall mural.

14. La Quinta Inn & Suites by Wyndham Amarillo Airport

Amarillo

Zane

NT$5,845 total

includes taxes & fees

Dec 3 - Dec 4

A spacious lobby with a modern design, featuring a seating area with colorful cushions, a large chandelier, and a flat-screen TV mounted on the wall.

15. Best Western Plus Medical Center

Amarillo

Michael

NT$3,821 total

includes taxes & fees

Nov 22 - Nov 23

An outdoor seating area with blue sofas, orange chairs, and a central fire feature.

16. Hampton Inn & Suites Dalhart

Dalhart

James

NT$5,333 total

includes taxes & fees

Nov 22 - Nov 23

An outdoor seating area with a fire pit, lounge chairs, and a building with large windows and a covered patio.

17. TownePlace Suites by Marriott Amarillo West/Medical Center

Amarillo

Mitchell

NT$5,818 total

includes taxes & fees

Nov 10 - Nov 11

A hotel entrance with a covered walkway, columns, and a sign for Holiday Inn Express & Suites.

18. Holiday Inn Express & Suites Amarillo by IHG

Amarillo

Terri

NT$4,722 total

includes taxes & fees

Nov 15 - Nov 16

A modern reception area with a desk, seating, and a large wall art piece.

19. City Express by Marriott Amarillo Northwest

Amarillo

Janet

NT$3,821 total

includes taxes & fees

Nov 20 - Nov 21

A swimming pool with clear water, a brick deck, and a waterfall feature.

20. Country Inn & Suites by Radisson, Amarillo I-40 West, TX

Amarillo

Sabine

NT$3,439 total

includes taxes & fees

Nov 22 - Nov 23

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Vacation Rentals in Panhandle Plains

Aparthotel

A cozy living room with a brown leather sofa, wooden flooring, a kitchen area with a microwave and refrigerator, and a doorway leading to a bedroom.

Life's Suites

Hamlin

"I very much enjoyed my stay here. Loved the room and would absolutely stay again."

Cottage

A modern kitchen with dark wooden cabinets, stainless steel appliances, and a central island with bar stools.

Fenced Yard: Modern Barndominium in Amarillo!

Amarillo

"Our stay was amazing, our host was wonderful, and the place was great too! While the owner is on the property too, we did not hear them and we ere able to come and go freely. It was a great stay! We would certainly stay here again!"

Aparthotel

A modern bar area with a wooden bar, stools, and a sofa.

Town Place Studio Extended Stay Snyder, TX

Snyder

"Nice place "

Aparthotel

A neatly arranged hotel room with a large bed, two bedside lamps, a telephone, and a wall-mounted light fixture.

Blue Bonnet Suites Extended Stay Lubbock, Texas

Lubbock

"This property is perfect for anyone planning a multi-day stay. The room was very clean and spacious, and the friendly staff made check-in a breeze. The amenities like the kitchen and double locks on door made our trip so much smoother and saved us a lot of extra planning. We would definitely choose to stay here again!"

Vacation Home

A spacious living room with a high ceiling, wooden beams, a fireplace, and a stone wall.

Stead House-3bd/2ba, Ttu, Fall Specials! 3 Bedroom Home by RedAwning

Lubbock

"The house was perfect for our needs. We had 8 people and there was plenty of space. Karen was so accommodating - leaving snacks and bringing over air mattresses when we needed one. She was very responsive and helpful in providing information on the area. We would stay there again!"

Vacation Home

A modern kitchen with a central island, built-in appliances, and a ceiling fan.

10 Minutes to Stadium Spacious 3BR Gameroom

Lubbock

"We loved the beds and the decor!"

Cottage

A covered deck with a view of a lake, a blue plastic chair, and two black chairs.

Cabin w/ Dock on Hubbard Creek Lake: Pets Welcome!

Breckenridge

"This is one of the best places I stayed at in years. They literally had everything you needed or want it, the host were amazing and hospitable, and went above and beyond for us. I promise you and your family will not be disappointed with your stay here. ."

Vacation Home

La Palma Guesthouse - Near Texas Tech

Lubbock

"Was a nice quiet location. Centrally located and wasn’t too far from anything in town. Good communication throughout our stay. "

Cottage

A modern kitchen with a dining area, featuring a round table, chairs, a chandelier, and a view of the backyard through glass doors.

Chic Home ~ 2 Mi to TTU w/ Grill & Yard in Lubbock

Tech Terrace

"Everything was great with this house. Very convenient to Tech (being in Tech Terrace) and a great neighborhood to walk around in. I contacted the host right when we arrived as we wanted to cool down the house, and she responded immediately. The inside door handle was broken which she apologized for, and I was able to make it work. But such an adorable place and I'd definitely return!"

Cottage

A bedroom with a bed, a ceiling fan, a nightstand with a lamp, a window with blinds, and a closet with hanging items.

Cozy Home W/fire Pit: Drive to Palo Duro Canyon!

Amarillo

"Very well equipped house located in a safe and convenient community."

Cottage

A spacious living area with a large sectional sofa, a round coffee table, and a view into the kitchen.

Outdoor Oasis w/ Lake Views: Ransom Canyon Retreat

Ransom Canyon

"This home has a beautiful lake view! We loved the patio and pool area and the outdoor grilling options."

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Stay near popular Panhandle Plains attractions

A large building with a tower and arched entrance.

Texas Tech University

9.4/10 (2,810 reviews)

Explore the campus of Texas Tech University, a top college in Lubbock. You can attend a sporting event while in the area.

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Learn more about Panhandle Plains

Big skies, big landscapes and a big welcome await in the northernmost region of Texas, a place characterized by its stunning frontier wilderness.

See all hotels in Panhandle Plains

A row of colorful, graffiti-covered benches in a desert setting.

Top Panhandle Plains Hotel Reviews

Ashmore Inn and Suites

8/10 Good

"For the price, this hotel was a good choice. We slept comfortably. We found ants in our bathroom, but once I notified the staff, they were eliminated. We finally figured out how to make the tv work…a combination of using the power and volume controls on the unit, and the remote. The breakfast on site included bread and eggs, so we ate at local restaurants. I’d stay there again."