Grand Isle, FL

Port St. Joe

A sunset over a body of water with a bridge in the background.

Grand Isle Hotel Deals

Comfort Suites

Comfort Suites

2.5 out of 5
264 N Tyndall Pkwy Panama City FL
The price is NT$2,539 per night from Nov 24 to Nov 25
NT$2,539
NT$2,744 total
Nov 24 - Nov 25
includes taxes & fees
Book a stay at this business-friendly hotel in Panama City. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. ...
8.4/10 Very Good! (830 reviews)
"Great location for a panhandle trip. Not overly expensive, good for a quick trip or families."

Reviewed on 2026/10/29

Comfort Suites
Holiday Inn Express Hotel & Suites Panama City-Tyndall by IHG

Holiday Inn Express Hotel & Suites Panama City-Tyndall by IHG

2.5 out of 5
5627 E Highway 22 State Route Panama City FL
The price is NT$2,853 per night from Nov 15 to Nov 16
NT$2,853
NT$3,083 total
Nov 15 - Nov 16
includes taxes & fees
Book a stay at this business-friendly hotel in Panama City. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. ...
8.6/10 Excellent! (538 reviews)
"Great for the price."

Reviewed on 2026/10/22

Holiday Inn Express Hotel & Suites Panama City-Tyndall by IHG
MainStay Suites Port Saint Joe South

MainStay Suites Port Saint Joe South

2.5 out of 5
3951 E Highway 98 Port St. Joe FL
The price is NT$3,767 per night from Nov 1 to Nov 2
NT$3,767
NT$4,219 total
Nov 1 - Nov 2
includes taxes & fees
Book a stay at this business-friendly hotel in Port St. Joe. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. ...
MainStay Suites Port Saint Joe South
Extended Stay America Select Suites - Panama City - Callaway

Extended Stay America Select Suites - Panama City - Callaway

2.5 out of 5
902 N Tyndall Parkway Panama City FL
Fully refundableReserve now, pay when you stay
The price is NT$2,186 per night from Nov 19 to Nov 20
NT$2,186
NT$2,363 total
Nov 19 - Nov 20
includes taxes & fees
Stay at this hotel in Panama City. Enjoy free WiFi, free parking, and laundry facilities. Popular attractions Veterans Park and Skater's Choice are located ...
Extended Stay America Select Suites - Panama City - Callaway
The Port Inn - Port St Joe, an Ascend Collection Hotel

The Port Inn - Port St Joe, an Ascend Collection Hotel

3.5 out of 5
501 Monument Ave. Port St. Joe FL
The price is NT$4,822 per night from Nov 4 to Nov 5
NT$4,822
NT$5,400 total
Nov 4 - Nov 5
includes taxes & fees
Stay at this hotel in Port St. Joe. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. Popular attractions ...
9/10 Wonderful! (480 reviews)
"The property is adorable and the staff was amazing. I really could not ask for a better experience."

Reviewed on 2026/10/26

The Port Inn - Port St Joe, an Ascend Collection Hotel
Driftwood Inn

Driftwood Inn

2 out of 5
2105 U.S. 98 Mexico Beach FL
The price is NT$5,821 per night from Nov 29 to Nov 30
NT$5,821
NT$6,520 total
Nov 29 - Nov 30
includes taxes & fees
Book a stay at this beach hotel in Port St. Joe. Enjoy free WiFi, free parking, and a beach locale. Popular attractions Mexico Beach Park and Mexico Beach are ...
Driftwood Inn
See all 2,273 properties in Grand Isle
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Where to stay in Grand Isle

Find the best Grand Isle areas and neighborhoods for the activities you enjoy most.
A marina at sunset with boats docked and a wooden pier.
Photo by Russell Hewatt
Open Photo by Russell Hewatt

Downtown Port St. Joe

While visiting Downtown Port St. Joe, you might make a stop by sights like Port Saint Joe City Hall and Constitution Convention Museum State Park.

A white house with a black roof, a white lighthouse with a black top, and a calm lake with purple flowers in the foreground.

Cape Breezes

While Cape Breezes isn't home to many top sights, T.H. Stone Memorial St. Joseph Peninsula State Park and St. Joseph Peninsula State Park are some notable places to visit nearby.

A beach with driftwood formations at sunset.

Gulf Aire

While Gulf Aire isn't home to many top sights, Saint Joe Beach and Mexico Beach are some notable places to visit nearby.

A sandy beach with calm waters and a large cloud in the sky.

Waterside Village

Though Waterside Village might not have many top sights, you can venture to the surrounding area to see attractions like Mexico Beach Marina and Mexico Beach.

A coastal landscape with tall grasses, a palm tree, and a sunset over the water.

Palms

While there might not be top attractions in Palms, you can explore the larger area and discover places like Mexico Beach and Mexico Beach Marina.

Grand Isle, FL