Photo by Hecktic Travels

Find Luxury Hotels in Mytilene

Start date: Check-in selected.
To Date
End date: Check-out
  • Change your mind

    Book hotels with free cancellation
  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
  • Be picky

    Search almost a million properties worldwide

Check availability on Mytilene Luxury Hotels

This weekend
Next weekend

Our top choices for Mytilene luxury hotels

Theofilos Paradise Boutique Hotel

Theofilos Paradise Boutique Hotel
4.0 star property
Lesvos
9.6 out of 10, Exceptional, (159)
"Our experience in here was so great! Staff is so kind and helpful. breakfast is the best and the location is the best 💙"
United Kingdom
Ezgi
Theofilos Paradise Boutique Hotel

Heliotrope Hotels

Heliotrope Hotels
4.0 star property
Lesvos
8.6 out of 10, Excellent, (192)
"Nice and clean hotel , very big breakfast buffet, easy parking"
United States
AVRAM
Heliotrope Hotels

The Loriet

The Loriet
4.0 star property
Lesvos
8.4 out of 10, Very Good, (76)
"Nice place, good breakfast"
United States
Emre
The Loriet

Mythical Coast Wellness Retreat

Mythical Coast Wellness Retreat
5.0 star property
Lesvos
8.6 out of 10, Excellent, (46)
"I booked a junior suite. The description does not match the room. The room was to have a balcony and it does not. It was a basic room of 30 square metres with two single beds pushed together and a chair and small table. The service was terrible. The person at teh front desk in the morning was rude and basically could not wait to get me out. This was out of character witht he wonderful hospitality elsewhere on the island. I would NEVER recommend this place. "
Canada
Alissa
Mythical Coast Wellness Retreat

Elysion Hotel

Elysion Hotel
5.0 star property
Lesvos
9.2 out of 10, Wonderful, (46)
"very good place and the staffs took very good care for us, even to prepare special diet foods. Lovely place and next to sea."
Turkey
ANINDYA
Elysion Hotel
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Top Mytilene Hotel Reviews

Frequently asked questions

Are you looking for a luxury hotel for your Mytilene vacation?
Mytilene has some interesting things to see and do including Port of Mytilene and Mytilini Castle, so you might want to take in the local sights during your visit.
What's the best luxury hotel in Mytilene?
Mythical Coast Wellness Retreat is a luxury hotel with 5 restaurants and 5 bars, and it's a popular choice for Expedia travelers looking for an elegant place to stay. Theofilos Paradise Boutique Hotel and Elysion Hotel are two other upscale options for your trip.
When can I expect good weather in Mytilene?
Planning for the weather is a good way to make your trip to Mytilene relaxing and enjoyable, especially when you're splurging. The hottest months are usually August and July with an average temp of 77°F, while the coldest months are January and February with an average of 52°F. Average annual precipitation for Mytilene is 34 inches.
What's there to see and do in Mytilene?
Take in the sights and attractions that Mytilene offers with a visit to Port of Mytilene, Mytilini Castle, and Thermi Beach. If you have a little extra time during your trip, you might want to make a stop at Roman Aqueduct at Moria and Museum of the Memorial of the Refugees of 1922.