A bridge spanning a body of water with a city skyline in the background during sunset.

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Our top choices for Mississippi River hotels

1. Sleep Inn & Suites Hannibal West

Sleep Inn & Suites Hannibal West
2.5 star property
30.3 km from Mississippi River
9.6 out of 10, Exceptional, (1,001 reviews)
"Great stay- within walking distance of good restaurant and coffee shop. Breakfast included hot items with adequate seating."
United States
ELAINE
The price is NT$3,426
NT$3,986 total
includes taxes & fees
Nov 25 - Nov 26
Sleep Inn & Suites Hannibal West

2. The Eagles Nest Inn

The Eagles Nest Inn
3.0 star property
14.2 km from Mississippi River
9.6 out of 10, Exceptional, (28 reviews)
"Cutest place to stay in Louisiana Missouri"
United States
Kimberly
The price is NT$3,814
NT$4,330 total
includes taxes & fees
Nov 2 - Nov 3
The Eagles Nest Inn

3. Best Western On The River

Best Western On The River
2.5 star property
25.3 km from Mississippi River
8.8 out of 10, Excellent, (1,008 reviews)
"fun town to stay and visit"
United States
Wei
The price is NT$3,585
NT$4,136 total
includes taxes & fees
Nov 6 - Nov 7
Best Western On The River

4. River's Edge Motel

River's Edge Motel
2.0 star property
13.6 km from Mississippi River
8.8 out of 10, Excellent, (395 reviews)
"Nice location."
United States
Jeff
The price is NT$2,869
NT$3,257 total
includes taxes & fees
Nov 2 - Nov 3
River's Edge Motel

5. Riverside Inn Hannibal

Riverside Inn Hannibal
2.5 star property
25.1 km from Mississippi River
9.6 out of 10, Exceptional, (204 reviews)
"Very nice room and great view of the river. Very comfortable bed and very nice shower. Walking distance to so many restaurants and shops. We enjoyed our stay very much!"
United States
Christina
The price is NT$4,944
NT$6,831 total
includes taxes & fees
Nov 3 - Nov 4
Riverside Inn Hannibal

6. Heritage Hotel Quincy

Heritage Hotel Quincy
2.0 star property
47.8 km from Mississippi River
8.6 out of 10, Excellent, (482 reviews)
"Clean room. Quiet and comfortable"
United States
GARY
The price is NT$2,539
NT$2,894 total
includes taxes & fees
Nov 15 - Nov 16
Heritage Hotel Quincy

7. Quality Inn & Suites Hannibal West

Quality Inn & Suites Hannibal West
2.5 star property
30 km from Mississippi River
8.0 out of 10, Very good, (1,002 reviews)
"Our go to hotel for years when we visit Hannibal."
United States
Gayle
The price is NT$2,426
NT$2,823 total
includes taxes & fees
Nov 29 - Nov 30
Quality Inn & Suites Hannibal West

8. Oak Hill Inn & Suites

Oak Hill Inn & Suites
2.5 star property
71.8 km from Mississippi River
9.2 out of 10, Wonderful, (1,003 reviews)
"It’s a great place to spend the night."
United States
Regina
The price is NT$3,063
NT$3,491 total
includes taxes & fees
Dec 1 - Dec 2
Oak Hill Inn & Suites

9. Stoney Creek Inn Quincy

Stoney Creek Inn Quincy
2.0 star property
46.5 km from Mississippi River
8.6 out of 10, Excellent, (1,004 reviews)
"The hotel was rustic, clean, and a great place to stay."
United States
Kent
The price is NT$3,184
NT$3,630 total
includes taxes & fees
Nov 8 - Nov 9
Stoney Creek Inn Quincy

10. Motel 6 Hannibal, MO

Motel 6 Hannibal, MO
2.0 star property
26.1 km from Mississippi River
7.4 out of 10, Good, (1,001 reviews)
"Excellent place to stay"
United States
Jared
The price is NT$1,890
NT$2,180 total
includes taxes & fees
Nov 3 - Nov 4
Motel 6 Hannibal, MO

11. Comfort Inn & Suites - Hannibal

Comfort Inn & Suites - Hannibal
2.5 star property
26.2 km from Mississippi River
7.6 out of 10, Good, (771 reviews)
"Front desk helpful Clean rooms Great breakfast and lady fixing our breakfast was helpful and kept plenty of food ready for all"
United States
Jerry
The price is NT$2,518
NT$3,002 total
includes taxes & fees
Nov 25 - Nov 26
Comfort Inn & Suites - Hannibal

12. Holiday Inn Quincy East by IHG

Holiday Inn Quincy East by IHG
3.0 star property
46.1 km from Mississippi River
8.8 out of 10, Excellent, (697 reviews)
"The hotel was in a great location with clean rooms."
United States
Colleen
The price is NT$3,618
NT$4,124 total
includes taxes & fees
Nov 29 - Nov 30
Holiday Inn Quincy East by IHG

13. Fairfield Inn & Suites Quincy

Fairfield Inn & Suites Quincy
3.0 star property
46 km from Mississippi River
8.6 out of 10, Excellent, (364 reviews)
"Room was clean, the breakfast buffet had a lot options."
United States
Chris
The price is NT$3,436
NT$3,916 total
includes taxes & fees
Nov 8 - Nov 9
Fairfield Inn & Suites Quincy

14. Quality Inn & Suites Quincy - Downtown

Quality Inn & Suites Quincy - Downtown
2.5 star property
47.8 km from Mississippi River
8.8 out of 10, Excellent, (498 reviews)
"Great stay for a wedding in the area."
United States
Bryan
The price is NT$4,160
NT$4,742 total
includes taxes & fees
Nov 8 - Nov 9
Quality Inn & Suites Quincy - Downtown

15. Lighthouse Inn & Suites

Lighthouse Inn & Suites
4.0 star property
25.8 km from Mississippi River
8.8 out of 10, Excellent, (47 reviews)
"The room was very clean. It had a hot tub in it and it was also very clean and worked properly. We enjoyed our stay there."
United States
Connie
The price is NT$5,504
NT$6,349 total
includes taxes & fees
Nov 2 - Nov 3
Lighthouse Inn & Suites

16. Super 8 by Wyndham Hannibal

Super 8 by Wyndham Hannibal
2.0 star property
26.3 km from Mississippi River
7.2 out of 10, Good, (1,003 reviews)
"Clean, safe hotel and friendly staff"
United States
Julie
The price is NT$2,013
NT$2,322 total
includes taxes & fees
Nov 15 - Nov 16
Super 8 by Wyndham Hannibal

17. Hampton Inn Keokuk

Hampton Inn Keokuk
2.5 star property
98.9 km from Mississippi River
8.8 out of 10, Excellent, (701 reviews)
"Great stay, clean rooms great breakfast"
United States
Ryan
The price is NT$3,297
NT$3,693 total
includes taxes & fees
Nov 22 - Nov 23
Hampton Inn Keokuk

18. Days Inn by Wyndham Hannibal

Days Inn by Wyndham Hannibal
2.0 star property
26.4 km from Mississippi River
7.4 out of 10, Good, (295 reviews)
"Pretty good place to stay at with a great price !!"
United States
Christian
The price is NT$2,200
NT$2,538 total
includes taxes & fees
Nov 2 - Nov 3
Days Inn by Wyndham Hannibal

19. Drury Inn & Suites St. Louis St. Peters

Drury Inn & Suites St. Louis St. Peters
3.0 star property
95.3 km from Mississippi River
9.6 out of 10, Exceptional, (1,004 reviews)
"All the people were very nice and talkative. The happy hour food was good and so were the cocktails. The hotel was clean and comfortable."
United States
Michael
The price is NT$3,585
NT$4,121 total
includes taxes & fees
Nov 22 - Nov 23
Drury Inn & Suites St. Louis St. Peters

20. Howard Johnson BY Wyndham Hannibal

Howard Johnson BY Wyndham Hannibal
2.0 star property
26.3 km from Mississippi River
7.4 out of 10, Good, (188 reviews)
"Great price! Nice comfortable clean room"
United States
Debbie
The price is NT$1,878
NT$2,180 total
includes taxes & fees
Dec 1 - Dec 2
Howard Johnson BY Wyndham Hannibal
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Compare popular hotels close to Mississippi River

Property
Property class
Guest rating
Breakfast included
Pool
Spa
Pet friendly
WiFi included
A Sleep Inn & Suites building with a covered entrance, stone facade, and a flag.
Sleep Inn & Suites Hannibal West
2.5 star property
9.6
Exceptional
1,001 reviews
View
A staircase with wooden steps and a wooden handrail, leading up a brick wall.
The Eagles Nest Inn
3.0 star property
9.6
Exceptional
28 reviews
View
A hotel room with a large bed, a separate bathroom with a bathtub, and a desk with a chair.
Best Western On The River
2.5 star property
8.8
Excellent
1,008 reviews
View
A hotel room with a bed, two sofas, a small table, a desk with a chair, a TV, and a potted plant.
River's Edge Motel
2.0 star property
8.8
Excellent
395 reviews
View
A room with a beige leather sofa, a wooden coffee table, a floor lamp, and a patterned carpet.
Riverside Inn Hannibal
2.5 star property
9.6
Exceptional
204 reviews
View

Top Mississippi River Hotel Reviews

Other attractions near Mississippi River

Find out more about Mississippi River

Top reasons to visit Mississippi River

  • Scenic River Views: Experience breathtaking sights along the majestic Mississippi River, including iconic landmarks like the Memphis Bridge.
  • Cultural Exploration: Immerse yourself in the rich history and vibrant culture of the Mississippi Delta and nearby cities like Minneapolis.
  • Outdoor Activities: Enjoy bird watching, leisurely floating, and family-friendly adventures in beautiful natural settings.
  • Historic Attractions: Discover charming historic houses, intriguing caves, and engaging museums throughout the region.
  • Cozy Accommodations: Choose from a variety of charming bed & breakfasts and guesthouses for a memorable stay.

Find great hotels near Mississippi River

Discover a variety of hotel accommodations along the picturesque Mississippi River, where you can choose from charming bed & breakfasts and cozy guesthouses. Ideal for families, couples, and history enthusiasts, these lodging options provide a unique blend of comfort and romantic appeal. Whether you’re interested in rustic wilderness cabins or modern amenities at places like the Hampton Inn, the Mississippi River has something to make your stay memorable.

  • Best Western On The River: Nestled in the heart of the city, Best Western On The River is a budget-friendly lodging option with a guest rating of 8.6 out of 10. Located 26km from the Mississippi River, this hotel is ideal for families and business travelers alike. It features child-friendly amenities, including a PoolGate, making it a great choice for those traveling with kids. Its central location allows easy access to local attractions and dining options, ensuring a convenient stay while exploring the area.
  • Super 8 by Wyndham Bowling Green: With a guest rating of 8.4 out of 10, Super 8 by Wyndham Bowling Green offers a budget-friendly stay just 24km from the Mississippi River. This motel is well-known for its complimentary breakfast options, including daily free breakfast and to-go breakfast services, making it a great start to your day. Entertainment options abound with multiple television channels available for guests to enjoy. The welcoming atmosphere and essential amenities make it a suitable choice for travelers seeking comfort on a budget.
  • River's Edge Motel: River's Edge Motel boasts a guest rating of 9.0 out of 10 and is located a mere 13km from the Mississippi River. This pet-friendly motel is perfect for travelers who want to bring their furry companions along. The property features accommodating pet policies, allowing for a seamless stay with your pets. Its rustic charm and proximity to the river create a warm and inviting atmosphere, making it an excellent option for those seeking a cozy getaway in a natural setting.

Where to stay near Mississippi River

Your vacation along the Mississippi River promises a delightful blend of friendly people and family-friendly activities. Explore vibrant cities like Minneapolis near the Minnesota River, or immerse yourself in the rich culture of the Mississippi Delta. Enjoy relaxing excursions along the main river and the scenic Iowa River, each offering unique experiences and warm hospitality. Get ready to create unforgettable memories in this beautiful region.

  • Louisiana: Louisiana is a charming city located 14km from the Mississippi River, offering a delightful mix of outdoor activities and scenic views. The city experiences a steady flow of visitors throughout the year, with peak times in April, July, and September. Travelers are drawn here for its romantic atmosphere and recreational opportunities. Enjoy the local theater scene or explore nearby entertainment venues. Notable attractions include the picturesque river, serene lake, and the expansive national state park, making Louisiana a perfect getaway for nature lovers and couples alike.
  • New Canton: Situated 11km away from the Mississippi River, New Canton is a quaint city that attracts visitors with its seasonal charm. The peak travel months are January to February, April, August, and November. Families often visit to enjoy the beautiful scenery and partake in outdoor activities. Golf enthusiasts will appreciate the local golf courses, while those interested in education can explore various learning opportunities. Key landmarks include the nearby river, tranquil lake, and a fascinating natural history museum, ensuring a well-rounded experience for all ages.
  • Rockport: Located 13km from the Mississippi River, Rockport is a vibrant city that offers a blend of outdoor adventures and family-friendly attractions. The city sees an influx of visitors during May, July, and September, making it a popular choice for those seeking a city-themed experience. Enjoy educational outings, catch a show at the local theater, or hit the golf course for a day of fun. Rockport’s notable landmarks include an urban park, an engaging history museum, and a modern college university, providing a unique cultural experience for travelers.

Things to do in Mississippi River

Shopping

In the Mississippi River area, visit the Riverwalk Marketplace for unique gifts and local crafts. If you're up for a drive, head to the Mall of America, about 24km away, featuring a wide range of shops and dining options for a fun shopping experience.

Recreation

Experience the tranquility of the River View Wellness Retreat, where you can indulge in yoga classes and spa treatments surrounded by nature. Enjoy leisurely strolls along the riverbanks and rejuvenate with guided meditation sessions to enhance your overall well-being.

At the Mississippi River Spa, immerse yourself in a soothing environment with massages and wellness therapies. Participate in outdoor activities like kayaking or biking along the scenic river trails for a refreshing blend of relaxation and adventure.

Adventure

The Mississippi River offers thrilling kayaking and canoeing experiences, allowing you to paddle through stunning landscapes. Explore vibrant wildlife on guided riverboat tours or try your hand at fishing in its bountiful waters. For a unique angle, consider a scenic bike ride along the riverfront trails.

Nightlife

The nightlife along the Mississippi River is vibrant and diverse. Enjoy live music at B.B. King's Blues Club in Memphis, or sip craft cocktails at Rooftop Bar in New Orleans. For a laid-back vibe, visit a local pub in Baton Rouge and soak in the lively atmosphere.

*Distances are measured in a straight line; actual driving distances may vary depending on the route.

Booking tips and Expedia advantages for Mississippi River

To save money during your visit to the Mississippi River, consider traveling between December and February for lower accommodation rates, with Sundays being the cheapest days to stay. Use Expedia to compare hotel prices and find exclusive offers, and consider bundling your hotel, flights, and activities for additional savings. Look for Eco-certified hotels for sustainable options. Also, explore free activities along the river, such as parks and walking trails, to enhance your experience without breaking the bank.

  • The most and least expensive months on average to stay in a hotel: The cheapest months to stay around Mississippi River are December to February, where the prices are slightly lower. This is in comparison to May to July, where prices are slightly higher.
  • The most and least expensive days on average to stay in a hotel: The least expensive day to stay around Mississippi River is Sunday. The most expensive day to stay around Mississippi River is Saturday.
  • Find cheap hotels on Expedia: Expedia's search tool enables you to choose your budget, desired location, and additional preferences. You can arrange your search results to display prices from lowest to highest, making it easy to find the most affordable hotels first. Additionally, you have the option to narrow down your choices by hotel type; for instance, selecting the Eco-certified filter will showcase sustainable and environmentally-friendly hotels that you can reserve.
  • Consider bundling your trip: You can save money by combining your hotel stay along the Mississippi River with your flights and activities through an Expedia package.

Find the best attractions near Mississippi River

The Mississippi River offers a variety of attractions, including historic houses, caves, and museums, perfect for travelers seeking culture, outdoor activities, and family experiences. Explore the majestic Mississippi River itself, the scenic Chippewa River, the iconic Memphis Bridge, and the tranquil Mississippi River headwaters for a memorable vacation experience along this mighty waterway.

  • Mark Twain Boyhood Home and Museum: Explore the childhood home of Samuel Clemens, known as Mark Twain, in Hannibal, Missouri. This museum offers a glimpse into the author's early life and the influences that shaped his literary career. With engaging exhibits and guided tours, visitors can immerse themselves in the culture and history of the area.
  • Mark Twain Cave: Venture into the historic Mark Twain Cave, a site of adventure and exploration. Just 23km from the Mississippi River, this cave features fascinating rock formations and a rich history tied to Twain's storytelling. Guided tours provide insight into its natural beauty and geological significance.
  • Mark Twain Memorial Lighthouse: Visit this historic lighthouse, which stands as a tribute to Mark Twain's legacy. Located 26km from the river, the lighthouse offers scenic views of the Mississippi and serves as a cultural landmark, celebrating the region's literary heritage.

The nearest major airports for your trip to Mississippi River

Traveling to the Mississippi River can be done via several major airports. St. Louis Lambert International Airport (STL), located 113km away, offers hotels like The Ritz-Carlton and Ameristar Casino Resort and Spa, both just 11km from the airport. Greater Peoria Regional Airport (PIA), 175km distant, has options like Embassy Suites by Hilton and Peoria Marriott Pere Marquette, both within 10km. Columbia Regional Airport (COU) is 122km away, with nearby accommodations such as The Broadway Columbia - a DoubleTree by Hilton and voco The Tiger Hotel, both around 18km from the airport. Each location provides convenient transportation services for easy access.

Frequently asked questions

What's the area like around Mississippi River?
Mississippi River is located in an area that travelers like for its baseball games. When you want to settle in and find a place to stay, check out some of the hotels and other accommodations that Expedia offers in the area.
What's the best place to stay close to Mississippi River?
Hollywood Casino & Hotel St. Louis is one of the top choices for your stay based on our traveler data, and this hotel offers a casino and 7 restaurants. You'll find it 65.7 mi (105.7 km) from Mississippi River. Other good options around the area include Hyatt Regency St. Louis at The Arch and Clayton Plaza Hotel & Extended Stay.
If I need to cancel the hotel reservation for my stay near Mississippi River, will I receive a refund?
Yes, you'll find most hotel reservations are refundable provided that you cancel before the accommodation's cancellation deadline, which in most cases is within 24 or 48 hours of your check-in date. If your reservation is non-refundable, you might still have the option to cancel and be given a refund within a 24-hour period of booking. Add your dates and click on "Search", then use the filter option "fully refundable" to get top deals close to Mississippi River.
Where can I learn more about changing or cancelling my trip in the area near Mississippi River?
For additional details about updating your stay near Mississippi River or cancelling it, head over to our customer service page.