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Sep 25 - Sep 27
Next weekend
Oct 2 - Oct 4

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Our top choices for Main Street Fort Pierce hotels

A hotel room with two beds, a small round table, and artwork depicting a beach scene and a zebra.

1. Redfinn Inn

Redfinn Inn
2.5 star property
0.7 km from Main Street Fort Pierce
6.4 out of 10, (418 reviews)
"Great newish renovated property, super clean very quiet excellent staff!"
United States
Robert
The price is NT$1,670
NT$1,871 total
includes taxes & fees
Sep 27 - Sep 28
Redfinn Inn
A spacious living area with a grey sofa, a blue sofa, and a wooden accent wall with a flat-screen TV.

2. La Quinta Inn & Suites by Wyndham Ft. Pierce

La Quinta Inn & Suites by Wyndham Ft. Pierce
3.0 star property
7.9 km from Main Street Fort Pierce
8.6 out of 10, Excellent, (1,000 reviews)
"Very clean friendly staff good breakfast"
United States
riad
The price is NT$2,792
NT$3,127 total
includes taxes & fees
Sep 29 - Sep 30
La Quinta Inn & Suites by Wyndham Ft. Pierce
A hotel lobby with a large reception desk, multiple seating areas, and a patterned carpet.

3. Fairfield Inn & Suites by Marriott Fort Pierce

Fairfield Inn & Suites by Marriott Fort Pierce
3.0 star property
7.7 km from Main Street Fort Pierce
8.8 out of 10, Excellent, (1,000 reviews)
"Nice hotel, good location"
United States
Wilmer
The price is NT$2,939
NT$3,292 total
includes taxes & fees
Oct 11 - Oct 12
Fairfield Inn & Suites by Marriott Fort Pierce
A hotel lobby with a long dining table, multiple chairs, and a coffee bar with various beverages.

4. Hampton Inn & Suites Ft. Pierce

Hampton Inn & Suites Ft. Pierce
2.5 star property
7.9 km from Main Street Fort Pierce
9.2 out of 10, Wonderful, (1,000 reviews)
"EVERYTHING WAS EXCELLENT"
United States
ROOSEVELT
The price is NT$3,096
NT$3,467 total
includes taxes & fees
Oct 25 - Oct 26
Hampton Inn & Suites Ft. Pierce
An outdoor seating area with fire feature, stone walls, and a view into the building.

5. Home2 Suites by Hilton Ft. Pierce I-95

Home2 Suites by Hilton Ft. Pierce I-95
3.0 star property
7.8 km from Main Street Fort Pierce
9.4 out of 10, Exceptional, (271 reviews)
The price is NT$3,616
NT$4,050 total
includes taxes & fees
Oct 25 - Oct 26
Home2 Suites by Hilton Ft. Pierce I-95
A pool area with lounge chairs and a hot tub, surrounded by palm trees and a view of the ocean.

6. Hutchinson Island Hotel

Hutchinson Island Hotel
2.5 star property
3.1 km from Main Street Fort Pierce
8.2 out of 10, Very good, (1,375 reviews)
"Great place to stay and enjoy the beach!"
United States
Kathleen
The price is NT$2,729
NT$3,639 total
includes taxes & fees
Sep 28 - Sep 29
Hutchinson Island Hotel
A multi-story building with a flat roof, parking lot, and a Red Roof sign.

7. Red Roof Inn Ft Pierce

Red Roof Inn Ft Pierce
2.0 star property
4.6 km from Main Street Fort Pierce
7.2 out of 10, Good, (816 reviews)
"Nice place to stay "
United States
Rhonise
The price is NT$2,760
NT$3,091 total
includes taxes & fees
Oct 7 - Oct 8
Red Roof Inn Ft Pierce
A restaurant interior with a bar area, wooden flooring, and multiple seating arrangements.

8. Days Inn & Suites by Wyndham Fort Pierce Midtown

Days Inn & Suites by Wyndham Fort Pierce Midtown
2.0 star property
4.5 km from Main Street Fort Pierce
7.0 out of 10, Good, (1,002 reviews)
"Good value"
United States
Cynthia
The price is NT$1,915
NT$2,144 total
includes taxes & fees
Sep 26 - Sep 27
Days Inn & Suites by Wyndham Fort Pierce Midtown
A modern reception area with a long corridor, a reception desk, and a seating area with tables and chairs.

9. Holiday Inn Express Hotel & Suites Fort Pierce West by IHG

Holiday Inn Express Hotel & Suites Fort Pierce West by IHG
2.5 star property
8.3 km from Main Street Fort Pierce
8.8 out of 10, Excellent, (888 reviews)
"We have stayed at this hotel before. We like the facility and staff"
United States
walter
The price is NT$3,109
NT$3,482 total
includes taxes & fees
Oct 25 - Oct 26
Holiday Inn Express Hotel & Suites Fort Pierce West by IHG
A hotel room with a bed, a sofa, and a small table. There are framed pictures on the wall.

10. Comfort Suites Fort Pierce I-95

Comfort Suites Fort Pierce I-95
2.5 star property
7.7 km from Main Street Fort Pierce
7.8 out of 10, Good, (965 reviews)
"Clean rooms, friendly staff"
United States
Marina
The price is NT$2,739
NT$3,067 total
includes taxes & fees
Sep 30 - Oct 1
Comfort Suites Fort Pierce I-95
A hotel entrance with a welcome sign, a black mat, and two potted plants.

11. At Home Inn

At Home Inn
2.5 star property
8.2 km from Main Street Fort Pierce
8.0 out of 10, Very good, (1,299 reviews)
"Love the hotel"
United States
Eric
The price is NT$1,820
NT$2,038 total
includes taxes & fees
Oct 25 - Oct 26
At Home Inn
A reception area with a wooden reception desk, a bulletin board with various notices, a window with blinds, and a wall-mounted security camera.

12. Rodeway Inn Fort Pierce US Highway 1

Rodeway Inn Fort Pierce US Highway 1
2.0 star property
2.9 km from Main Street Fort Pierce
6.8 out of 10, (124 reviews)
"Clean room, convenient location"
United States
Natalia
The price is NT$2,562
NT$2,869 total
includes taxes & fees
Sep 26 - Sep 27
Rodeway Inn Fort Pierce US Highway 1
A hotel lobby with a reception desk, a chandelier, a clock, and a sofa.

13. Sleep Inn Fort Pierce I-95

Sleep Inn Fort Pierce I-95
2.5 star property
7.9 km from Main Street Fort Pierce
7.6 out of 10, Good, (911 reviews)
"Staff was very friendly and rooms were clean"
United States
Charity
The price is NT$1,995
NT$2,235 total
includes taxes & fees
Oct 1 - Oct 2
Sleep Inn Fort Pierce I-95
A modern bar area with wooden tables and blue chairs, featuring black pendant lights and a large abstract mural on the wall.

14. TownePlace Suites by Marriott Port St. Lucie I-95

TownePlace Suites by Marriott Port St. Lucie I-95
3.0 star property
21.9 km from Main Street Fort Pierce
9.4 out of 10, Exceptional, (1,005 reviews)
"Super clean and easy place to stay, near everything, large parking, nice pool."
Canada
Bernard
The price is NT$3,397
NT$3,805 total
includes taxes & fees
Sep 28 - Sep 29
TownePlace Suites by Marriott Port St. Lucie I-95
A lakeside property with a dock, palm trees, and RVs.

15. Road Runner Travel Resort - Caravan Park

Road Runner Travel Resort - Caravan Park
2.5 star property
7 km from Main Street Fort Pierce
9.4 out of 10, Exceptional, (102 reviews)
"Our family had an amazing stay, the pool was fun, everyone was friendly and our cabin was the perfect fit. "
United States
Benjamin
The price is NT$5,551
NT$6,218 total
includes taxes & fees
Sep 25 - Sep 26
Road Runner Travel Resort - Caravan Park
A swimming pool with lounge chairs and a table, surrounded by palm trees and a fence.

16. Motel 6 Ft. Pierce, FL, Fort Pierce

Motel 6 Ft. Pierce, FL, Fort Pierce
2.0 star property
7.3 km from Main Street Fort Pierce
5.6 out of 10, (1,006 reviews)
"The rooms are always clean and my favorite part is the fact this place is pet friendly to all."
United States
Caitlin
The price is NT$1,744
NT$2,017 total
includes taxes & fees
Sep 25 - Sep 26
Motel 6 Ft. Pierce, FL, Fort Pierce
A clear blue swimming pool with lounge chairs and umbrellas, surrounded by palm trees and a gazebo.

17. Best Western Port St. Lucie

Best Western Port St. Lucie
2.5 star property
14 km from Main Street Fort Pierce
8.6 out of 10, Excellent, (1,001 reviews)
"Clean comfortable beds I would come back"
United States
Andrew
The price is NT$2,712
NT$3,037 total
includes taxes & fees
Oct 7 - Oct 8
Best Western Port St. Lucie
A hotel lobby with a reception desk, seating area, and a hallway leading to other rooms.

18. Days Inn & Suites by Wyndham Fort Pierce I-95

Days Inn & Suites by Wyndham Fort Pierce I-95
2.5 star property
7.8 km from Main Street Fort Pierce
7.4 out of 10, Good, (1,000 reviews)
"The staff was excellent"
United States
Carlton
The price is NT$1,875
NT$2,100 total
includes taxes & fees
Sep 27 - Sep 28
Days Inn & Suites by Wyndham Fort Pierce I-95
A Holiday Inn Express & Suites hotel with a modern design, featuring a prominent entrance, well-maintained landscaping, and a clear view of the sky.

19. Holiday Inn Express & Suites Port St. Lucie West by IHG

Holiday Inn Express & Suites Port St. Lucie West by IHG
2.5 star property
17.1 km from Main Street Fort Pierce
8.6 out of 10, Excellent, (1,001 reviews)
"All the staff was incredibly gelding and accommodating for anything we asked."
United States
Laurie
The price is NT$3,204
NT$3,588 total
includes taxes & fees
Sep 27 - Sep 28
Holiday Inn Express & Suites Port St. Lucie West by IHG
An outdoor patio area with a fire pit, red and black wicker furniture, and string lights.

20. Residence Inn by Marriott Port St. Lucie

Residence Inn by Marriott Port St. Lucie
3.0 star property
17.8 km from Main Street Fort Pierce
9.0 out of 10, Wonderful, (1,000 reviews)
"Great place to stay"
United States
Eduardo
The price is NT$3,204
NT$3,588 total
includes taxes & fees
Sep 28 - Sep 29
Residence Inn by Marriott Port St. Lucie
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties

Where to stay in Main Street Fort Pierce

Find the best Main Street Fort Pierce areas and neighborhoods for the activities you enjoy most.
A coastal area with a narrow waterway, a beach, and residential buildings.

Lakewood Park

While Lakewood Park isn't home to many top sights, Lakewood Park Regional Park / Pool and McKee Botanical Garden are some notable places to visit nearby.

Spanish Lakes Country Club Village

While there might not be top attractions in Spanish Lakes Country Club Village, you can explore the larger area and discover places like Lakewood Park Regional Park / Pool and Harbor Branch Ocean Discovery Center.

A calm lake reflecting trees and a clear sky.

Spanish Lakes Fairways

While Spanish Lakes Fairways might not have many sights to explore, venturing just a little farther will lead you to top things to see and do like Lakewood Park Regional Park / Pool and Endless Summer Vineyard & Winery.

A coastal city with a bay, mangrove islands, and a clear blue sky.

Meadowood

If you're looking for some top things to see and do in Meadowood and surrounding area, you can visit Lakewood Park Regional Park / Pool and Endless Summer Vineyard & Winery.

A mosaic sign with 'Mainstreet Fort Pierce' written on it.

Panther Woods

If you're looking for some top things to see and do in Panther Woods and surrounding area, you can visit Lakewood Park Regional Park / Pool and Endless Summer Vineyard & Winery.

Top Main Street Fort Pierce Hotel Reviews

Hampton Inn & Suites Port St. Lucie, West

Hampton Inn & Suites Port St. Lucie, West

10/10 Excellent
"Plenty of parking. Rooms are clean, staff are friendly. Housekeeping could know how long a guest is staying and allow enough toilet paper in the room and provide a bar of soap. Breakfast included in your stay is always nice. Thank you"
Sharon 4-night trip
Posted 2 hours ago
Hampton Inn & Suites Port St. Lucie, West

Frequently asked questions

What is Main Street Fort Pierce like?
Main Street Fort Pierce is a neighborhood that travelers like for its waterfront, art, and shopping. Be sure to check out Sunrise Theater and Fort Pierce City Marina as part of your Main Street Fort Pierce travel plans.
How many hotels can I expect to find in Main Street Fort Pierce?
Book one of Expedia's 7 hotels and other accommodations in Main Street Fort Pierce and start exploring everything Fort Pierce has to offer.
If I need to cancel my hotel reservation in Main Street Fort Pierce, will I receive a refund?
Yes! The majority of hotel reservations are fully refundable provided that you cancel before the hotel's cancellation deadline, which often is within 24-48 hours of the scheduled arrival. If you booked a non-refundable reservation, you might be able to cancel it and be given a refund within 24 hours of booking. Put your dates in and click on "Search", then use the filter option "fully refundable" to review the top deals on offer in Main Street Fort Pierce.
Where can I learn more about changing or cancelling my trip to Main Street Fort Pierce?
For additional details about changing or cancelling your trip to Main Street Fort Pierce, head over to our customer service page.
What is there to do in this Fort Pierce neighborhood?
Sights like Sunrise Theater and Official Highwaymen Art Gallery can be part of your cultural tour of Main Street Fort Pierce. Fort Pierce City Marina and Fort Pierce Farmer's Market are also a couple of places to visit in the neighborhood. A few places to visit in the area around Main Street Fort Pierce include Manatee Education and Observation Center, House of Seven Gables, and A.E. Backus Museum. Marina at Fort Pierce and Causeway Cove are also worth a visit when you're out sightseeing in Fort Pierce.

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