What is Main Street Fort Pierce like?

Main Street Fort Pierce is a neighborhood that travelers like for its waterfront, art, and shopping. Be sure to check out Sunrise Theater and Fort Pierce Farmer's Market as part of your Main Street Fort Pierce travel plans.

How many hotels can I expect to find in Main Street Fort Pierce?

Book one of Expedia's 7 hotels and other accommodations in Main Street Fort Pierce and start exploring everything Fort Pierce has to offer.

If I need to cancel my hotel reservation in Main Street Fort Pierce, will I receive a refund?

Yes! The majority of hotel reservations are fully refundable provided that you cancel before the hotel’s cancellation deadline, which often is within 24-48 hours of the scheduled arrival. If you booked a non-refundable reservation, you might be able to cancel it and be given a refund within 24 hours of booking. Put your dates in and click on "Search", then use the filter option "fully refundable" to review the top deals on offer in Main Street Fort Pierce.

Where can I learn more about changing or cancelling my trip to Main Street Fort Pierce?

For additional details about changing or cancelling your trip to Main Street Fort Pierce, head over to our customer service page .

What is there to do in this Fort Pierce neighborhood?

Sights like Sunrise Theater and Official Highwaymen Art Gallery can be part of your cultural tour of Main Street Fort Pierce. Fort Pierce Farmer's Market and Fort Pierce City Marina are also a couple of places to visit in the neighborhood. A few places to visit in the area around Main Street Fort Pierce include Manatee Education and Observation Center, House of Seven Gables, and A.E. Backus Museum. Marina at Fort Pierce and Causeway Cove are also worth a visit when you're out sightseeing in Fort Pierce.

Top Main Street Fort Pierce Hotels

Change your mind
Book hotels with free cancellation
Treat yourself
Sign in to save 10% or more on thousands of hotels
Sign in
Be picky
Search almost a million properties worldwide

Check prices for these dates

Tonight

Tomorrow

This weekend

Next weekend

Our top choices for Main Street Fort Pierce hotels

A hotel lobby with a large reception desk, multiple seating areas, and a patterned carpet.

1. Fairfield Inn & Suites by Marriott Fort Pierce

7.7 km from Main Street Fort Pierce

NT$3,309 total

includes taxes & fees

Oct 22 - Oct 23

A hotel lobby with a long dining table, multiple chairs, and a coffee bar with various beverages.

2. Hampton Inn & Suites Ft. Pierce

7.9 km from Main Street Fort Pierce

Angela

NT$3,466 total

includes taxes & fees

Nov 1 - Nov 2

A modern reception area with a long corridor, a reception desk, and a seating area with tables and chairs.

3. Holiday Inn Express Hotel & Suites Fort Pierce West by IHG

8.3 km from Main Street Fort Pierce

Iosif

NT$3,613 total

includes taxes & fees

Nov 8 - Nov 9

An outdoor seating area with fire feature, stone walls, and a view into the building.

4. Home2 Suites by Hilton Ft. Pierce I-95

7.8 km from Main Street Fort Pierce

JERRY

NT$4,228 total

includes taxes & fees

Oct 25 - Oct 26

A pool area with lounge chairs and a hot tub, surrounded by palm trees and a view of the ocean.

5. Hutchinson Island Hotel

3.1 km from Main Street Fort Pierce

Kathleen

NT$3,857 total

includes taxes & fees

Oct 18 - Oct 19

A spacious living area with a grey sofa, a blue sofa, and a wooden accent wall with a flat-screen TV.

6. La Quinta Inn & Suites by Wyndham Ft. Pierce

7.9 km from Main Street Fort Pierce

riad

NT$3,143 total

includes taxes & fees

Oct 15 - Oct 16

A hotel lobby with a reception desk, seating area, and a hallway leading to other rooms.

7. Days Inn & Suites by Wyndham Fort Pierce I-95

7.8 km from Main Street Fort Pierce

Carlton

NT$2,185 total

includes taxes & fees

Oct 25 - Oct 26

A hotel room with a bed, a sofa, and a small table. There are framed pictures on the wall.

8. Comfort Suites Fort Pierce I-95

7.7 km from Main Street Fort Pierce

Marina

NT$3,015 total

includes taxes & fees

Nov 1 - Nov 2

A hotel entrance with a welcome sign, a black mat, and two potted plants.

9. At Home Inn

8.2 km from Main Street Fort Pierce

Ronald

NT$2,052 total

includes taxes & fees

Nov 7 - Nov 8

A modern living room with a fireplace, a dining area with bar stools, and a large TV mounted on the wall.

10. Hampton Inn & Suites Vero Beach Downtown

22.1 km from Main Street Fort Pierce

Cameron

NT$4,664 total

includes taxes & fees

Nov 1 - Nov 2

A clear blue swimming pool with lounge chairs and umbrellas, surrounded by palm trees and a gazebo.

11. Best Western Port St. Lucie

14 km from Main Street Fort Pierce

BRIAN

NT$3,219 total

includes taxes & fees

Oct 25 - Oct 26

A spacious hotel lobby with seating areas, a kitchenette, and large windows.

12. Hampton Inn & Suites Port St. Lucie, West

17.4 km from Main Street Fort Pierce

Nensie

NT$3,456 total

includes taxes & fees

Oct 23 - Oct 24

A Holiday Inn Express & Suites hotel with a modern design, featuring a prominent entrance, well-maintained landscaping, and a clear view of the sky.

13. Holiday Inn Express & Suites Port St. Lucie West by IHG

17.1 km from Main Street Fort Pierce

NT$4,078 total

includes taxes & fees

Oct 18 - Oct 19

A hotel lobby with a reception desk, a chandelier, a clock, and a sofa.

14. Sleep Inn Fort Pierce I-95

7.9 km from Main Street Fort Pierce

Charity

NT$2,785 total

includes taxes & fees

Nov 1 - Nov 2

A multi-story hotel with a modern design, featuring a prominent sign for 'Springhill Suites Marriott'.

15. SpringHill Suites Port St. Lucie

17.2 km from Main Street Fort Pierce

NT$3,664 total

includes taxes & fees

Oct 21 - Oct 22

A spacious lobby with a stone fireplace, comfortable seating, and a bar area.

16. Staybridge Suites Vero Beach by IHG

24.1 km from Main Street Fort Pierce

Christine

NT$4,436 total

includes taxes & fees

Oct 11 - Oct 12

A restaurant interior with a bar area, wooden flooring, and multiple seating arrangements.

17. Days Inn & Suites by Wyndham Fort Pierce Midtown

4.5 km from Main Street Fort Pierce

NT$2,186 total

includes taxes & fees

Oct 19 - Oct 20

A hotel room with two beds, a television, a ceiling fan, and a view of the beach.

18. The Royal Inn Beach Hotel Hutchinson Island

3.8 km from Main Street Fort Pierce

Taylor

NT$4,899 total

includes taxes & fees

Oct 12 - Oct 13

An outdoor patio area with a fire pit, red and black wicker furniture, and string lights.

19. Residence Inn by Marriott Port St. Lucie

17.8 km from Main Street Fort Pierce

NT$3,613 total

includes taxes & fees

Oct 18 - Oct 19

A reception area with wooden paneling, a large circular artwork on the wall, and a reception desk.

20. Fairfield Inn & Suites by Marriott Vero Beach

28.4 km from Main Street Fort Pierce

CARLOS

NT$3,460 total

includes taxes & fees

Oct 22 - Oct 23

View all properties

Where to stay in Main Street Fort Pierce

Find the best Main Street Fort Pierce areas and neighborhoods for the activities you enjoy most.

A coastal area with a narrow waterway, a beach, and residential buildings.

Lakewood Park

While Lakewood Park isn't home to many top sights, McKee Botanical Garden and Avalon State Park are some notable places to visit nearby.

See properties

Spanish Lakes Country Club Village

While there might not be top attractions in Spanish Lakes Country Club Village, you can explore the larger area and discover places like Harbor Branch Ocean Discovery Center and McKee Botanical Garden.

See properties

A calm lake reflecting trees and a clear sky.

Spanish Lakes Fairways

While Spanish Lakes Fairways might not have many sights to explore, venturing just a little farther will lead you to top things to see and do like Lakewood Park Regional Park / Pool and Indrio Road Park / Schoolhouse.

See properties

A coastal city with a bay, mangrove islands, and a clear blue sky.

Meadowood

If you're looking for some top things to see and do in Meadowood and surrounding area, you can visit Endless Summer Vineyard & Winery and Al's Family Farms.

See properties

A mosaic sign with 'Mainstreet Fort Pierce' written on it.

Panther Woods

If you're looking for some top things to see and do in Panther Woods and surrounding area, you can visit Endless Summer Vineyard & Winery and Al's Family Farms.

See properties

Top Main Street Fort Pierce Hotel Reviews

Marriott Hutchinson Island Resort & Beach Villas, Golf & Marina

8/10 Good

"Nice facility Coffee maker not working well Staff excellent!!"

Find hotels in Main Street Fort Pierce, Fort Pierce

Change your mind

Treat yourself

Be picky

Check prices for these dates

Filter by

Star rating

Guest rating

Our top choices for Main Street Fort Pierce hotels

1. Fairfield Inn & Suites by Marriott Fort Pierce

2. Hampton Inn & Suites Ft. Pierce

3. Holiday Inn Express Hotel & Suites Fort Pierce West by IHG

4. Home2 Suites by Hilton Ft. Pierce I-95

5. Hutchinson Island Hotel

6. La Quinta Inn & Suites by Wyndham Ft. Pierce

7. Days Inn & Suites by Wyndham Fort Pierce I-95

8. Comfort Suites Fort Pierce I-95

9. At Home Inn

10. Hampton Inn & Suites Vero Beach Downtown

11. Best Western Port St. Lucie

12. Hampton Inn & Suites Port St. Lucie, West

13. Holiday Inn Express & Suites Port St. Lucie West by IHG

14. Sleep Inn Fort Pierce I-95

15. SpringHill Suites Port St. Lucie

16. Staybridge Suites Vero Beach by IHG

17. Days Inn & Suites by Wyndham Fort Pierce Midtown

18. The Royal Inn Beach Hotel Hutchinson Island

19. Residence Inn by Marriott Port St. Lucie

20. Fairfield Inn & Suites by Marriott Vero Beach

Where to stay in Main Street Fort Pierce

Lakewood Park

Spanish Lakes Country Club Village

Spanish Lakes Fairways

Meadowood

Panther Woods

Top Main Street Fort Pierce Hotel Reviews

Marriott Hutchinson Island Resort & Beach Villas, Golf & Marina

Frequently asked questions

Explore a world of travel with Expedia