A gazebo with a green roof, surrounded by a pond, with red and green foliage in the background.

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Oct 9 - Oct 11
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Oct 16 - Oct 18

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Our top choices for Mackenzie hotels

A modern hotel lobby with a reception desk, seating area, and a refreshment bar.

1. SpringHill Suites St. Louis Brentwood

SpringHill Suites St. Louis Brentwood
3.0 star property
4.9 km from Mackenzie
9.0 out of 10, Wonderful, (1,000 reviews)
"Staff was very friendly and rooms were clean."
United States
Aaron
The price is NT$3,668
NT$4,328 total
includes taxes & fees
Oct 18 - Oct 19
SpringHill Suites St. Louis Brentwood
A restaurant with round tables and chairs, a bar area, and a patterned ceiling.

2. Drury Plaza Hotel St. Louis Brentwood

Drury Plaza Hotel St. Louis Brentwood
4.0 star property
5.8 km from Mackenzie
9.6 out of 10, Exceptional, (1,003 reviews)
"Excellent place to stay. Beautiful hotel, amazing friendly and attentive staff. Would highly recommend!!"
United States
Janell
The price is NT$4,228
NT$5,020 total
includes taxes & fees
Nov 1 - Nov 2
Drury Plaza Hotel St. Louis Brentwood
An outdoor patio with a fire pit, seating, and a building in the background.

3. Courtyard by Marriott St. Louis Brentwood

Courtyard by Marriott St. Louis Brentwood
3.0 star property
5.5 km from Mackenzie
9.4 out of 10, Exceptional, (906 reviews)
"We were in town for a Haloween event and this location was close to our venue. The property was lovely and clean and beds were comfy. The best part of our stay was the staff though. Our check in process was amazing, the bar tender in the evening was fantastic and the person running the breakfast area was beyond friendly. Would stay here again without hesitation."
United States
Gretchen
The price is NT$3,756
NT$4,581 total
includes taxes & fees
Oct 18 - Oct 19
Courtyard by Marriott St. Louis Brentwood
A bar area with a long counter displaying numerous bottles of alcohol and several empty wine glasses lined up.

4. Holiday Inn St Louis SW - Route 66 by IHG

Holiday Inn St Louis SW - Route 66 by IHG
3.0 star property
8.5 km from Mackenzie
9.2 out of 10, Wonderful, (585 reviews)
"I like the hotel completely. The cleanliness and staff and restaurant were amazing"
United States
Eric
The price is NT$3,751
NT$4,462 total
includes taxes & fees
Oct 11 - Oct 12
Holiday Inn St Louis SW - Route 66 by IHG
A swimming pool with a metal ladder, surrounded by chairs and large windows offering a view of the sunset.

5. La Quinta Inn & Suites by Wyndham St Louis Route 66

La Quinta Inn & Suites by Wyndham St Louis Route 66
3.0 star property
8.3 km from Mackenzie
8.4 out of 10, Very good, (1,009 reviews)
"Friendly staff clean facility il be back to the hot tub and breakfast"
United States
Tiffany
The price is NT$3,162
NT$3,675 total
includes taxes & fees
Oct 8 - Oct 9
La Quinta Inn & Suites by Wyndham St Louis Route 66
A hotel room with a minibar, a shoe rack, a coat rack, and a TV.

6. Holiday Inn Express & Suites St. Louis South - I-55 by IHG

Holiday Inn Express & Suites St. Louis South - I-55 by IHG
2.5 star property
11.2 km from Mackenzie
9.6 out of 10, Exceptional, (1,000 reviews)
"Room was clean staff friendly"
United States
Thomas
The price is NT$3,974
NT$4,569 total
includes taxes & fees
Oct 11 - Oct 12
Holiday Inn Express & Suites St. Louis South - I-55 by IHG
A long bar with multiple tables and chairs, wooden floors, and ornate chandeliers.

7. River City Casino & Hotel

River City Casino & Hotel
4.0 star property
7.3 km from Mackenzie
9.2 out of 10, Wonderful, (1,811 reviews)
"Great accommodations - highly recommend"
United States
jodi
The price is NT$3,162
NT$4,175 total
includes taxes & fees
Oct 26 - Oct 27
River City Casino & Hotel
An indoor swimming pool with lounge chairs and a pool table, surrounded by large windows.

8. Hampton Inn & Suites St. Louis at Forest Park

Hampton Inn & Suites St. Louis at Forest Park
3.5 star property
Dogtown, 6.2 km from Mackenzie
9.4 out of 10, Exceptional, (1,000 reviews)
"This was an excellent location and the front desk staff made great recommendations for places to eat and things to do."
United States
Jennifer
The price is NT$4,666
NT$5,503 total
includes taxes & fees
Oct 26 - Oct 27
Hampton Inn & Suites St. Louis at Forest Park
A modern lobby with a stone fireplace, blue sofas, and potted plants.

9. Comfort Suites St. Louis - Sunset Hills

Comfort Suites St. Louis - Sunset Hills
2.5 star property
8.4 km from Mackenzie
9.0 out of 10, Wonderful, (237 reviews)
"Nice place, had everything we needed"
United States
John
The price is NT$3,754
NT$4,364 total
includes taxes & fees
Oct 19 - Oct 20
Comfort Suites St. Louis - Sunset Hills
A modern living room with a sofa set, a coffee table, and a TV mounted on the wall.

10. Fairfield Inn & Suites by Marriott St. Louis South

Fairfield Inn & Suites by Marriott St. Louis South
3.0 star property
11.3 km from Mackenzie
9.6 out of 10, Exceptional, (395 reviews)
"Loved the super clean hotel.. Comfortable beds , big t v, FABULOUS breakfast every morning.. GREAT LOCATION, we will come again and recommend to everyone"
United States
Megan
The price is NT$3,691
NT$4,244 total
includes taxes & fees
Nov 1 - Nov 2
Fairfield Inn & Suites by Marriott St. Louis South
A spacious lobby with multiple seating areas, a central coffee table, and artwork on the walls.

11. Best Western St. Louis-Kirkwood Route 66

Best Western St. Louis-Kirkwood Route 66
3.5 star property
8.1 km from Mackenzie
8.2 out of 10, Very good, (1,567 reviews)
"The room was perfect and the hotel is pet friendly so we could bring our dog."
United States
Sonja
The price is NT$3,061
NT$3,582 total
includes taxes & fees
Oct 11 - Oct 12
Best Western St. Louis-Kirkwood Route 66
A lobby with a reception desk, seating area, and a bicycle in the background.

12. Drury Inn & Suites St. Louis Forest Park

Drury Inn & Suites St. Louis Forest Park
3.0 star property
4.7 km from Mackenzie
9.4 out of 10, Exceptional, (1,020 reviews)
"Great place to stay"
United States
Robert
The price is NT$4,291
NT$5,018 total
includes taxes & fees
Nov 1 - Nov 2
Drury Inn & Suites St. Louis Forest Park
An outdoor seating area with a fire pit, cushioned benches, and a covered patio with string lights.

13. Home2 Suites by Hilton St. Louis/Forest Park

Home2 Suites by Hilton St. Louis/Forest Park
3.0 star property
The Grove, 7.4 km from Mackenzie
8.6 out of 10, Excellent, (1,004 reviews)
"Staff was nice and helpful food was great and room was amazing!!! "
United States
paullita jeanne
The price is NT$4,943
NT$5,780 total
includes taxes & fees
Nov 1 - Nov 2
Home2 Suites by Hilton St. Louis/Forest Park
The Clayton Plaza Hotel sign with a stone wall and plants in front.

14. Clayton Plaza Hotel & Extended Stay

Clayton Plaza Hotel & Extended Stay
3.5 star property
7.8 km from Mackenzie
9.0 out of 10, Wonderful, (3,453 reviews)
"Great location, lots of things to do in the area and the staff was amazing!"
United States
Daniele
The price is NT$2,913
NT$3,400 total
includes taxes & fees
Oct 25 - Oct 26
Clayton Plaza Hotel & Extended Stay
A modern dining area with multiple tables and chairs, recessed ceiling lights, and a kitchen in the background.

15. Best Western Plus Fenton

Best Western Plus Fenton
2.5 star property
12.2 km from Mackenzie
9.0 out of 10, Wonderful, (464 reviews)
"Breakfast was great! Staff was super helpful and friendly, and the room was clean and comfortable."
United States
Brian
The price is NT$3,214
NT$3,712 total
includes taxes & fees
Oct 15 - Oct 16
Best Western Plus Fenton
A cozy lounge area with leather sofas, a fireplace, and a bar counter.

16. The Cheshire

The Cheshire
4.0 star property
5.9 km from Mackenzie
8.8 out of 10, Excellent, (1,000 reviews)
"Fantastic hotel, clean and nice rooms, great breakfast and location"
United States
Matthew
The price is NT$4,718
NT$5,602 total
includes taxes & fees
Oct 25 - Oct 26
The Cheshire
A courtyard with outdoor seating, a central fountain, and a view of a tower.

17. The Knight Center at Washington University

The Knight Center at Washington University
2.5 star property
7.7 km from Mackenzie
9.4 out of 10, Exceptional, (697 reviews)
"Beautiful hotel and very clean. We had a wonderful stay!"
United States
Rosalyn
The price is NT$5,377
NT$6,183 total
includes taxes & fees
Oct 11 - Oct 12
The Knight Center at Washington University
A spacious lobby with a high ceiling, modern lighting fixtures, a seating area with sofas and chairs, and a bar area with stools.

18. Hampton Inn & Suites St. Louis/South I-55

Hampton Inn & Suites St. Louis/South I-55
2.5 star property
11.2 km from Mackenzie
9.6 out of 10, Exceptional, (1,004 reviews)
"Quiet at night no road noise. Hallways quiet, very comfortable beds. Breakfast was good!"
United States
Kevin
The price is NT$3,361
NT$3,865 total
includes taxes & fees
Oct 18 - Oct 19
Hampton Inn & Suites St. Louis/South I-55
A rooftop restaurant with round tables, chairs, and a view of the city.

19. Moonrise Hotel

Moonrise Hotel
4.0 star property
8.4 km from Mackenzie
9.0 out of 10, Wonderful, (2,030 reviews)
"Great location"
United States
Katherine
The price is NT$4,196
NT$4,991 total
includes taxes & fees
Oct 19 - Oct 20
Moonrise Hotel
A modern interior with hanging pendant lights, large windows, and a view of the outside.

20. Heritage Inn & Suites St. Louis/Fenton, Trademark by Wyndham

Heritage Inn & Suites St. Louis/Fenton, Trademark by Wyndham
3.0 star property
13.8 km from Mackenzie
7.8 out of 10, Good, (1,589 reviews)
"Great place"
United States
Dashaun
The price is NT$2,836
NT$3,275 total
includes taxes & fees
Nov 2 - Nov 3
Heritage Inn & Suites St. Louis/Fenton, Trademark by Wyndham
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties

Where to stay in Mackenzie

Find the best Mackenzie areas and neighborhoods for the activities you enjoy most.
The Gateway Arch in St. Louis, Missouri, with a well-maintained lawn and trees in the foreground.

Downtown St. Louis

Ample dining options, fascinating museums, and great live music are just a few top things to explore in Downtown St. Louis. A visit to Old Courthouse or Gateway Arch National Park might round out your trip, and you can jump aboard the metro at 8th and Pine Station or Stadium Station to get around town.

A gazebo by a calm pond with autumn foliage and clear skies.

Clayton

Visitors often come to Clayton for its abundant dining options, but many stay to explore sights like Chapel of St. Timothy And St. Titus, Concordia Seminary and Shaw Park Tennis Center. Getting around the area on the metro is easy if you catch a ride at Clayton Station.

A historic building with a green dome and adjacent modern high-rise buildings.

Central West End

Bordering Forest Park with free cultural institutions, this St. Louis neighborhood boasts a bustling commercial district along Euclid Avenue and the world's largest mosaic collection at the Cathedral Basilica of Saint Louis.

A wooden bridge with metal trusses, surrounded by trees.

St. Charles Historic District

Discover a national historic district featuring over 100 buildings, including the First Missouri State Capitol and St. Charles Odd Fellows Hall, showcasing architectural styles like Greek Revival and Italianate.

A lake with a curved shoreline, a parking lot, and a forested area with autumn foliage.

Creve Coeur

Creve Coeur is known for its abundant dining options, and you can plan a trip to Creve Coeur Golf Club and Skip Viragh Center for the Arts while you're in town.

Top Mackenzie Hotel Reviews

Moonrise Hotel

Moonrise Hotel

10/10 Excellent
"I love the Moonrise and will stay here anytime I come to St. Louis. I have stayed here multiple times and never had a negative experience. Easy parking, walking to food, next door to concert venues, plus pet friendly. The rooftop bar is great too!"
Rachel 1-night trip
Posted 14 hours ago
Moonrise Hotel

Frequently asked questions

What's it like in Mackenzie?
Travelers will be sure to find plenty to entertain them in St. Louis's Mackenzie neighborhood.
If I need to cancel my hotel reservation in Mackenzie, will I receive a refund?
Yes! Most hotel bookings are fully refundable if cancelled before the hotel's cancellation deadline, which often is within 24-48 hours of your arrival date. If you have a non-refundable reservation, you might be able to still cancel and get a refund within 24 hours of booking. Add dates, click "Search", then filter by "fully refundable" to review the top deals on offer in Mackenzie.
Where can I learn more about changing or cancelling my trip to Mackenzie?
To access more information about changing or cancelling your trip to Mackenzie, go to https://www.expedia.com/service/.
What is there to do in this St. Louis neighborhood?
Lindenwood Park, Repertory Theatre of St. Louis, and River des Peres Greenway Trailhead are just a few of the places to visit in and around Mackenzie. While you're out sightseeing, The Focal Point and Webster Groves Tennis Center are a couple of additional sights to visit in St. Louis.

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