Photo by Brittany Cabler

Find hotels in Lakeshore South, Jacksonville

Start date: Check-in selected.
To Date
End date: Check-out

  • Change your mind

    Book hotels with free cancellation

  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
    Sign in

  • Be picky

    Search almost a million properties worldwide

Check prices for these dates

Tonight
Dec 27 - Dec 28
Tomorrow
Dec 28 - Dec 29
Next weekend
Jan 2 - Jan 4
In two weeks
Jan 9 - Jan 11

Filter by

Guest rating
Guest rating
Star rating

Our top choices for Lakeshore South hotels

Property amenity
Sheraton Jacksonville Hotel

Sheraton Jacksonville Hotel

Sheraton Jacksonville Hotel
4.0 star property
Deerwood, 18.3 km from Lakeshore South
9.2 out of 10, Wonderful, (1004)
"Great stay and great customer service"
United States
Rebecca
The price is NT$2,918
NT$3,312 total
includes taxes & fees
Dec 28 - Dec 29
Sheraton Jacksonville Hotel
Exterior
Holiday Inn Express & Suites Jacksonville - Town Center by IHG

Holiday Inn Express & Suites Jacksonville - Town Center by IHG

Holiday Inn Express & Suites Jacksonville - Town Center by IHG
2.5 star property
Southside, 19.6 km from Lakeshore South
9.6 out of 10, Exceptional, (1002)
"Great hotel"
United States
Nima
The price is NT$4,119
NT$4,675 total
includes taxes & fees
Jan 11 - 2026/1/12
Holiday Inn Express & Suites Jacksonville - Town Center by IHG
Sports facility
Hyatt Place Jacksonville / St. Johns Town Center

Hyatt Place Jacksonville / St. Johns Town Center

Hyatt Place Jacksonville / St. Johns Town Center
3.0 star property
Southside, 18.9 km from Lakeshore South
9.2 out of 10, Wonderful, (1002)
"Quiet, near a lot of restaurants and shopping and all within walking distance. Staff was very friendly."
United States
Amber
The price is NT$3,873
NT$4,395 total
includes taxes & fees
Dec 30 - Dec 31
Hyatt Place Jacksonville / St. Johns Town Center
Exterior
Hampton Inn Jacksonville/Ponte Vedra Beach-Mayo Clinic Area

Hampton Inn Jacksonville/Ponte Vedra Beach-Mayo Clinic Area

Hampton Inn Jacksonville/Ponte Vedra Beach-Mayo Clinic Area
2.5 star property
31.5 km from Lakeshore South
9.0 out of 10, Wonderful, (1001)
"Good location for exploring Ponte Vedra and Jacksonville Beach areas."
United States
Julianne
The price is NT$3,834
NT$4,352 total
includes taxes & fees
Jan 4 - 2026/1/5
Hampton Inn Jacksonville/Ponte Vedra Beach-Mayo Clinic Area
Reception
Tru by Hilton Jacksonville South Mandarin

Tru by Hilton Jacksonville South Mandarin

Tru by Hilton Jacksonville South Mandarin
2.5 star property
14.1 km from Lakeshore South
9.0 out of 10, Wonderful, (1004)
"Excellent staff and hotel "
United States
Edward
The price is NT$2,810
NT$3,189 total
includes taxes & fees
Jan 4 - 2026/1/5
Tru by Hilton Jacksonville South Mandarin
Terrace/patio
TownePlace Suites by Marriott Jacksonville East

TownePlace Suites by Marriott Jacksonville East

TownePlace Suites by Marriott Jacksonville East
3.0 star property
Golden Glades - The Woods, 25.7 km from Lakeshore South
9.2 out of 10, Wonderful, (550)
"Very good hotel"
United States
Careli
The price is NT$3,583
NT$4,067 total
includes taxes & fees
Jan 4 - 2026/1/5
TownePlace Suites by Marriott Jacksonville East
Daily buffet breakfast (USD 26.95 per person)
Hyatt Regency Jacksonville

Hyatt Regency Jacksonville

Hyatt Regency Jacksonville
4.0 star property
Downtown Jacksonville, 8.1 km from Lakeshore South
9.0 out of 10, Wonderful, (1400)
"Great stay "
United States
terria
The price is NT$5,029
NT$5,766 total
includes taxes & fees
Dec 28 - Dec 29
Hyatt Regency Jacksonville
Meeting facility
Hilton Garden Inn Jacksonville JTB/Deerwood Park

Hilton Garden Inn Jacksonville JTB/Deerwood Park

Hilton Garden Inn Jacksonville JTB/Deerwood Park
3.0 star property
Southside, 16.6 km from Lakeshore South
9.0 out of 10, Wonderful, (1000)
"Front desk staff very professional and helpful "
United States
Erika
The price is NT$3,326
NT$3,775 total
includes taxes & fees
Jan 11 - 2026/1/12
Hilton Garden Inn Jacksonville JTB/Deerwood Park
Lobby
Southbank Hotel by Marriott Jacksonville Riverwalk

Southbank Hotel by Marriott Jacksonville Riverwalk

Southbank Hotel by Marriott Jacksonville Riverwalk
3.5 star property
Southbank, 7.7 km from Lakeshore South
8.2 out of 10, Very Good, (1622)
"The breakfast was really good, cook to order for a fee but the prices were decent. "
United States
BRIAN
The price is NT$3,225
NT$3,661 total
includes taxes & fees
Jan 11 - 2026/1/12
Southbank Hotel by Marriott Jacksonville Riverwalk
Lobby
Comfort Inn & Suites Jacksonville - Orange Park Near Naval Air Station

Comfort Inn & Suites Jacksonville - Orange Park Near Naval Air Station

Comfort Inn & Suites Jacksonville - Orange Park Near Naval Air Station
2.5 star property
Westside, 9.3 km from Lakeshore South
9.4 out of 10, Exceptional, (1003)
"Wonderful place to stay. "
United States
Millie
The price is NT$3,317
NT$3,764 total
includes taxes & fees
Jan 11 - 2026/1/12
Comfort Inn & Suites Jacksonville - Orange Park Near Naval Air Station
Exterior
DoubleTree by Hilton Hotel Jacksonville Airport

DoubleTree by Hilton Hotel Jacksonville Airport

DoubleTree by Hilton Hotel Jacksonville Airport
4.0 star property
Northside, 23.5 km from Lakeshore South
8.4 out of 10, Very Good, (1713)
"Friendly helpful staff, clean rooms, great service. "
United States
Tabitha
The price is NT$3,196
NT$3,628 total
includes taxes & fees
Jan 11 - 2026/1/12
DoubleTree by Hilton Hotel Jacksonville Airport
Free daily buffet breakfast
Holiday Inn Express Jacksonville Beach by IHG

Holiday Inn Express Jacksonville Beach by IHG

Holiday Inn Express Jacksonville Beach by IHG
3.0 star property
31 km from Lakeshore South
9.2 out of 10, Wonderful, (1000)
"Great location "
United States
Angel
The price is NT$3,616
NT$4,104 total
includes taxes & fees
Jan 6 - 2026/1/7
Holiday Inn Express Jacksonville Beach by IHG
Lobby
Hyatt Place Jacksonville Airport

Hyatt Place Jacksonville Airport

Hyatt Place Jacksonville Airport
3.0 star property
Northside, 23.1 km from Lakeshore South
9.0 out of 10, Wonderful, (2296)
"Nice and clean hotel, good breakfast, had a comfortable stay."
United States
Krishna
The price is NT$3,458
NT$3,925 total
includes taxes & fees
Jan 12 - 2026/1/13
Hyatt Place Jacksonville Airport
Exterior
Hotel Indigo Jacksonville-Deerwood Park by IHG

Hotel Indigo Jacksonville-Deerwood Park by IHG

Hotel Indigo Jacksonville-Deerwood Park by IHG
3.5 star property
Southside, 16.7 km from Lakeshore South
9.2 out of 10, Wonderful, (1001)
"Very nice stay "
United States
Timmothy
The price is NT$3,580
NT$4,064 total
includes taxes & fees
Dec 28 - Dec 29
Hotel Indigo Jacksonville-Deerwood Park by IHG
Daily buffet breakfast for a fee
Tru By Hilton Jacksonville St Johns Town Center

Tru By Hilton Jacksonville St Johns Town Center

Tru By Hilton Jacksonville St Johns Town Center
2.5 star property
Southside, 18.8 km from Lakeshore South
9.0 out of 10, Wonderful, (826)
"Staff very friendly. "
United States
Rhonda
The price is NT$3,427
NT$3,890 total
includes taxes & fees
Dec 28 - Dec 29
Tru By Hilton Jacksonville St Johns Town Center
Lobby
Hilton Jacksonville At Mayo Clinic

Hilton Jacksonville At Mayo Clinic

Hilton Jacksonville At Mayo Clinic
4.5 star property
27.1 km from Lakeshore South
9.4 out of 10, Exceptional, (81)
"Great place to stay"
United States
Judy
The price is NT$4,609
NT$5,232 total
includes taxes & fees
Dec 30 - Dec 31
Hilton Jacksonville At Mayo Clinic
Exterior
Home2 Suites by Hilton Jacksonville Airport

Home2 Suites by Hilton Jacksonville Airport

Home2 Suites by Hilton Jacksonville Airport
3.0 star property
Northside, 23.2 km from Lakeshore South
8.6 out of 10, Excellent, (1002)
"Clean room and friendly staff"
United States
Marlene
The price is NT$3,441
NT$3,906 total
includes taxes & fees
Jan 1 - 2026/1/2
Home2 Suites by Hilton Jacksonville Airport
Studio, 2 Queen Beds, Accessible, Non Smoking | Living area | 43-inch LCD TV with satellite channels, TV
Hampton Inn & Suites Jacksonville Deerwood Park

Hampton Inn & Suites Jacksonville Deerwood Park

Hampton Inn & Suites Jacksonville Deerwood Park
2.5 star property
Southside, 16.2 km from Lakeshore South
9.4 out of 10, Exceptional, (1001)
"Great stay"
United States
Mary Jean
The price is NT$3,325
NT$3,774 total
includes taxes & fees
Jan 4 - 2026/1/5
Hampton Inn & Suites Jacksonville Deerwood Park
Exterior
Comfort Suites Jacksonville Airport

Comfort Suites Jacksonville Airport

Comfort Suites Jacksonville Airport
2.5 star property
Northside, 23.3 km from Lakeshore South
8.2 out of 10, Very Good, (897)
"I had a nice experience staying here. Staff is friendly and professional, hotel is nice and clean, decent breakfast included, overall this was a nice stay for the price! I would stay again for sure.. "
United States
Kevin
The price is NT$2,959
NT$3,359 total
includes taxes & fees
Dec 28 - Dec 29
Comfort Suites Jacksonville Airport
Exterior
Hampton Inn & Suites Jacksonville / Orange Park

Hampton Inn & Suites Jacksonville / Orange Park

Hampton Inn & Suites Jacksonville / Orange Park
2.5 star property
10.6 km from Lakeshore South
8.8 out of 10, Excellent, (721)
"Clean and very organized hotel"
United States
Diobe
The price is NT$3,325
NT$3,741 total
includes taxes & fees
Jan 4 - 2026/1/5
Hampton Inn & Suites Jacksonville / Orange Park
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties

Where to stay in Lakeshore South

Find the best Lakeshore South areas and neighborhoods for the activities you enjoy most.
Downtown Jacksonville which includes skyline, a city and a river or creek
Photo by Ryan Ketterman
Open Photo by Ryan Ketterman

Downtown Jacksonville

Historic core with major corporations, Downtown Jacksonville offers diverse culinary and nightlife experiences at The Elbow. Explore attractions like Florida Theatre, TIAA Bank Field, and museums, while enjoying convenient transportation options.

Amelia City

While visiting Amelia City, you might make a stop by sights like American Beach and Fernandina Beach.

Southside

If you're spending some time in Southside, St. Johns Town Center and Orange Park Place Shopping Center are top sights worth seeing.

Sawgrass

Visitors to Sawgrass like its beaches and riverfront, and Mickler Beach is a sight worth a stop.

Cummer Museum of Art and Gardens which includes interior views and art as well as a couple
Photo by Visit Jacksonville
Open Photo by Visit Jacksonville

Northwest

If you're spending some time in Northwest, Cummer Museum of Art and Gardens and Jacksonville-Baldwin Rail Trail are top sights worth seeing.

Top Lakeshore South Hotel Reviews

Holiday Inn Express & Suites Jacksonville Airport by IHG

Holiday Inn Express & Suites Jacksonville Airport by IHG

10/10 Excellent
"Staff was very helpful and friendly "
Pamela 2-night trip
Posted 1 day ago
Holiday Inn Express & Suites Jacksonville Airport by IHG

Frequently asked questions

What's it like in Lakeshore South?
Travelers to the Lakeshore South neighborhood in Jacksonville will be sure to enjoy their stay. Are you looking for Lakeshore South travel tips? Be sure to check out Ortega Yacht Club Marina and Lambs Marina while you're in the neighborhood.
How many hotels should I expect to find in the Lakeshore South area?
Expedia has 34 hotels and other accommodations in Lakeshore South to choose from, making this an ideal home base for exploring the greater Jacksonville area.
If I need to cancel my hotel reservation in Lakeshore South, will I receive a refund?
Yes, most room reservations are fully refundable if cancelled prior to the accommodation's cancellation deadline, which often is within 24-48 hours of the scheduled arrival. If you booked a non-refundable reservation, you might be able to cancel it and get a refund within 24 hours of booking. Plug in your dates, click on "Search", then you can use the "fully refundable" filter to review the top deals on offer in Lakeshore South.
Where can I learn more about changing or cancelling my trip to Lakeshore South?
For additional details about updating your trip to Lakeshore South or cancelling it, head over to our customer service page.
What can I see and do in this Jacksonville neighborhood?
If you've got some time for activities in Lakeshore South, you won't be disappointed by Ortega Yacht Club Marina, Lambs Marina, and Sadler Point Marina. You could also plan a visit to Ceder Point Marina or Museum of Southern History while you're in the neighborhood. A few places to visit in the area around Lakeshore South include Pine Wood Park, Lighthouse Marina, and Cedar Hills Shopping Center. When you're sightseeing in Jacksonville, Hyde Park Golf Club and Paxon Shopping Center are also worth a stop.

Explore a world of travel with Expedia