Find Luxury Hotels in Isle of Palms, FL

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Our top choices for Isle of Palms luxury hotels

The Villas of Amelia Island

The Villas of Amelia Island
4.0 star property
Fernandina Beach
8.4 out of 10, Very Good, (1130)
"We have stayed at this property every year for the past decade. We have always enjoyed our time out here with family. Highly recommend catching morning sunrise from the beach. The vibe is very pleasant and accommodating, you will not be disapppointed. "
United States
Harsha
The price is NT$5,025
NT$7,042 total
includes taxes & fees
Dec 25 - Dec 26
The Villas of Amelia Island

Sheraton Jacksonville Hotel

Sheraton Jacksonville Hotel
4.0 star property
Southside
9.2 out of 10, Wonderful, (1009)
"Great stay and great customer service"
United States
Rebecca
The price is NT$3,005
NT$3,410 total
includes taxes & fees
Dec 28 - Dec 29
Sheraton Jacksonville Hotel

One Ocean Resort and Spa

One Ocean Resort and Spa
4.5 star property
Atlantic Beach
9.0 out of 10, Wonderful, (1002)
"Clean rooms and very nice staff "
United States
Arthur
The price is NT$5,473
NT$7,229 total
includes taxes & fees
Dec 30 - Dec 31
One Ocean Resort and Spa

Hyatt Regency Jacksonville

Hyatt Regency Jacksonville
4.0 star property
Downtown Jacksonville
9.0 out of 10, Wonderful, (1404)
"Great stay "
United States
terria
The price is NT$4,545
NT$5,210 total
includes taxes & fees
Dec 29 - Dec 30
Hyatt Regency Jacksonville

World Golf Village Renaissance St. Augustine Resort

World Golf Village Renaissance St. Augustine Resort
4.0 star property
St. Augustine
8.6 out of 10, Excellent, (1005)
"The hotel was very well-kept and the service was excellent! The restaurant in the hotel was a bit basic but it was nice to have the option if necessary. The bar and the resort shop were very nice as well."
United States
Jane
The price is NT$4,261
NT$4,751 total
includes taxes & fees
Jan 7 - 2026/1/8
World Golf Village Renaissance St. Augustine Resort

Hilton Jacksonville At Mayo Clinic

Hilton Jacksonville At Mayo Clinic
4.5 star property
Jacksonville
9.2 out of 10, Wonderful, (73)
"Great place to stay"
United States
Judy
The price is NT$4,115
NT$4,671 total
includes taxes & fees
Dec 30 - Dec 31
Hilton Jacksonville At Mayo Clinic

The Lodge and Club at Ponte Vedra Beach

The Lodge and Club at Ponte Vedra Beach
5.0 star property
Ponte Vedra Beach
9.4 out of 10, Exceptional, (688)
"Clean room, excellent service and only steps from the ocean. The facility could use some TLC but, all in all, a wonderful place to stay. We’ll be back for sure. "
United States
Robert
The price is NT$12,593
NT$14,957 total
includes taxes & fees
Jan 3 - 2026/1/4
The Lodge and Club at Ponte Vedra Beach

Springhill Suites By Marriott Jacksonville Beach Oceanfront

Springhill Suites By Marriott Jacksonville Beach Oceanfront
4.0 star property
Jacksonville Beach
9.0 out of 10, Wonderful, (620)
"Loved staying here. Great hotel. Very clean. The check-in process was smooth and Jay was awesome. I would recommend!"
United States
Kedric
The price is NT$5,081
NT$5,767 total
includes taxes & fees
Dec 29 - Dec 30
Springhill Suites By Marriott Jacksonville Beach Oceanfront

Marriott Jacksonville Downtown

Marriott Jacksonville Downtown
4.0 star property
Downtown Jacksonville
8.4 out of 10, Very Good, (1004)
"Safe and very nice I can’t wait to come back "
United States
Bertelmy
The price is NT$3,997
NT$4,537 total
includes taxes & fees
Dec 28 - Dec 29
Marriott Jacksonville Downtown

Ponte Vedra Inn & Club

Ponte Vedra Inn & Club
5.0 star property
Ponte Vedra Beach
9.4 out of 10, Exceptional, (813)
"Wonderful place to visit to relax. Very clean, very friendly and courteous staff. Great view from the balcony."
United States
Greg
The price is NT$12,593
NT$14,957 total
includes taxes & fees
Jan 4 - 2026/1/5
Ponte Vedra Inn & Club
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Top Isle of Palms Hotel Reviews

Frequently asked questions

Are you searching for the perfect hotel for your luxury getaway to Isle of Palms?
Use Expedia to help you arrange a flight to Jacksonville, FL (CRG-Jacksonville Executive at Craig) airport or Jacksonville International Airport (JAX) airport, and then choose from a variety of places to stay that will deliver the luxury you want. Amenities are important when you plan a vacation, so we make it easy to get what you need to make your stay special. If you want an upscale hotel that has fine dining, a spa, or several swimming pools, Expedia can help you find the best luxury hotel experience that Isle of Palms offers.
What's there to see and do in Isle of Palms?
When you're in Isle of Palms, enjoy exploring the sights and attractions here including St. Johns Town Center, Adventure Landing, and Oceanfront Park. If you have a little extra time during your trip, you might want to check out Northeast Florida Beaches and Jacksonville Beach Pier.

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