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Find Resorts & Hotels with Spas in Greenville, MS

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Our top choices for Greenville hotels with a spa

1. Hotel 27

Hotel 27
2.0 star property
Greenville
9.0 out of 10, Wonderful, (377 reviews)
"Had a lovely time at this property, we will be back to visit."
United States
Rachel
The price is NT$3,490
NT$3,839 total
includes taxes & fees
Nov 10 - Nov 11
Hotel 27

2. Holiday Inn Express and Suites Greenville by IHG

Holiday Inn Express and Suites Greenville by IHG
2.5 star property
Greenville
8.0 out of 10, Very good, (780 reviews)
"The front desk associates were very friendly and accommodating. We enjoyed our stay and will stay again in the future."
United States
Annette
The price is NT$4,529
NT$4,982 total
includes taxes & fees
Dec 2 - Dec 3
Holiday Inn Express and Suites Greenville by IHG

3. Americas Best Value Inn & Suites Greenville

Americas Best Value Inn & Suites Greenville
2.0 star property
Greenville
6.6 out of 10, (595 reviews)
"Parking was great, and there were great restaurants right down the street."
United States
Cedric
The price is NT$2,216
NT$2,437 total
includes taxes & fees
Nov 7 - Nov 8
Americas Best Value Inn & Suites Greenville

4. Econo Lodge Greenville

Econo Lodge Greenville
2.0 star property
Greenville
5.6 out of 10, (291 reviews)
"I liked the free breakfast. Staff did everything asked of them."
United States
Darryl M
The price is NT$1,939
NT$2,133 total
includes taxes & fees
Nov 23 - Nov 24
Econo Lodge Greenville

5. Days Inn by Wyndham Greenville MS

Days Inn by Wyndham Greenville MS
2.0 star property
Greenville
5.2 out of 10, (1,003 reviews)
"I had a great stay at this hotel! The room was nice and clean, the staff was friendly, and everything went smoothly. I enjoyed my stay and would definitely recommend this hotel to anyone looking for a nice place to stay. I would stay here again!"
United States
Kennedy
The price is NT$1,955
NT$2,150 total
includes taxes & fees
Nov 17 - Nov 18
Days Inn by Wyndham Greenville MS

6. Cotton House, Cleveland, a Tribute Portfolio Hotel

Cotton House, Cleveland, a Tribute Portfolio Hotel
3.5 star property
Cleveland
9.0 out of 10, Wonderful, (722 reviews)
"Everything was beautiful I enjoyed my stay. The staff was friendly and very catering to my needs. The rooms are beautiful."
United States
Monica
The price is NT$4,822
NT$5,256 total
includes taxes & fees
Nov 8 - Nov 9
Cotton House, Cleveland, a Tribute Portfolio Hotel

7. Tru By Hilton Greenville

Tru By Hilton Greenville
2.5 star property
Greenville
8.0 out of 10, Very good, (645 reviews)
"We really enjoyed our stay at the Tru Blue Hilton in Greenville. The town, people, and local attractions were easily accessible, and we liked the convenience of the hotel to downtown."
United States
Joan
The price is NT$3,981
NT$4,379 total
includes taxes & fees
Dec 1 - Dec 2
Tru By Hilton Greenville

8. Harlow's Casino Resort & Spa

Harlow's Casino Resort & Spa
3.5 star property
Greenville
7.8 out of 10, Good, (1,003 reviews)
"The service and staff were very polite friendly and kind. We will definitely return"
United States
LaTonya
The price is NT$3,783
NT$4,161 total
includes taxes & fees
Nov 8 - Nov 9
Harlow's Casino Resort & Spa

9. Lyric Hotel West End, Trademark Collection by Wyndham

Lyric Hotel West End, Trademark Collection by Wyndham
3.0 star property
Cleveland
8.4 out of 10, Very good, (342 reviews)
"Clean facilities, comfortable bed."
United States
Britiani
The price is NT$4,076
NT$4,443 total
includes taxes & fees
Nov 8 - Nov 9
Lyric Hotel West End, Trademark Collection by Wyndham

10. Motel 6 Cleveland, MS - Delta State University

Motel 6 Cleveland, MS - Delta State University
2.0 star property
Cleveland
8.2 out of 10, Very good, (340 reviews)
"Clean, comfy, good location"
United States
Richelle
The price is NT$2,391
NT$2,607 total
includes taxes & fees
Nov 5 - Nov 6
Motel 6 Cleveland, MS - Delta State University

11. Quality Inn Indianola

Quality Inn Indianola
2.5 star property
Indianola
7.6 out of 10, Good, (176 reviews)
"Clean"
United States
Dennis
The price is NT$2,083
NT$2,270 total
includes taxes & fees
Nov 24 - Nov 25
Quality Inn Indianola

12. Americas Best Value Inn Indianola

Americas Best Value Inn Indianola
2.5 star property
Indianola
7.6 out of 10, Good, (221 reviews)
"The room was clean and smelled very fresh."
United States
Nathaniel
The price is NT$2,379
NT$2,593 total
includes taxes & fees
Nov 8 - Nov 9
Americas Best Value Inn Indianola

13. Super 8 by Wyndham Indianola

Super 8 by Wyndham Indianola
2.0 star property
Indianola
7.4 out of 10, Good, (416 reviews)
"Staff was helpful and parking was plentiful breakfast was okay, a cut back from previous stay."
United States
Mary
The price is NT$2,639
NT$2,877 total
includes taxes & fees
Nov 15 - Nov 16
Super 8 by Wyndham Indianola

14. Holiday Inn Express Hotel & Suites Cleveland by IHG

Holiday Inn Express Hotel & Suites Cleveland by IHG
2.5 star property
Cleveland
7.8 out of 10, Good, (1,003 reviews)
"The property is clean and well maintained even though it is under renovation. It was still clean and the staff is phenomenal. They are very attentive and welcoming. Breakfast and the coffee are so good! My stay was great and I will be returning!"
United States
Kwanza
The price is NT$3,682
NT$4,013 total
includes taxes & fees
Dec 4 - Dec 5
Holiday Inn Express Hotel & Suites Cleveland by IHG

15. c towninn and suites

c towninn and suites
2.0 star property
Cleveland
5.6 out of 10, (32 reviews)
"Rm clean air work not professional at all. I will not stay again"
United States
Angela
The price is NT$1,613
NT$1,758 total
includes taxes & fees
Nov 4 - Nov 5
c towninn and suites

16. Hampton Inn

Hampton Inn
2.0 star property
Indianola
The price is NT$4,956
NT$5,848 total
includes taxes & fees
Nov 8 - Nov 9
Hampton Inn
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Choose what matters most at spa hotels in Greenville

Find out more about Greenville

Top Greenville attractions for a relaxing vacation

In Greenville, Mississippi, travelers with a penchant for spa hotels can indulge in a range of relaxing activities. Start your journey at the picturesque Lake Ferguson, where serene views provide the perfect backdrop for a laid-back afternoon of fishing or kayaking. For a taste of local culture, the Delta Blues Museum offers a deep dive into the area’s rich musical heritage, making for an inspiring visit. Don’t miss the chance to explore the vibrant downtown area, where charming boutiques and art galleries invite leisurely strolls. After a day of exploring, unwind at one of the local hotels offering spa services, such as the historic Greenville Inn, known for its attentive service and rejuvenating treatments. Enjoying a stay here not only provides easy access to the town's attractions but also ensures a pampering experience, perfect for those who appreciate quality and comfort.

Find the best hotels & resorts with spas in Greenville

Travelers seeking relaxation and rejuvenation in Greenville, Mississippi will find a selection of hotels that cater to their spa needs. Each hotel offers unique treatments and tranquil environments for a restorative experience.

Harlow's Casino Resort & Spa

  • Why it's great for tailored spa getaway: For travelers looking to unwind in style, Harlow's Casino Resort & Spa is an ideal destination, a guest review rating of 7.8. This resort features a full-service spa where guests can indulge in a variety of treatments, including Swedish massages, aromatherapy, and detoxification wraps, ensuring a soothing escape from everyday stress.
  • Other amenities: In addition to its spa services, Harlow's offers a range of amenities to enhance the stay. Guests can enjoy a relaxing dip in the pool, stay fit at the 24-hour fitness center, or indulge in gourmet dining options. The resort provides free self-parking, daily housekeeping, and features luxurious Egyptian cotton sheets and premium bedding in its accommodations.
  • Nearby attractions: Mississippi River - 3.32 miles, Harlow's Casino Resort & Spa - 0.47 miles, Warfield Point Park - 2.75 miles

Top Greenville Hotel Reviews

Frequently asked questions

Looking to vacation at a spa hotel in Greenville?
Forget the stress of everyday life and book yourself a lush spa hotel. Check out the live music scene and restaurants in Greenville—your day trip starts here. Enjoy the entertainment choices and riverfront during your vacation. Spa hotels are the perfect way to break away from your daily routine and add a layer of luxury to your weekend away.
What is the best spa hotel in Greenville?
Harlow's Casino Resort & Spa is a top spa hotel featuring 3 restaurants, 3 bars, a casino, and a 24-hour fitness center. Enjoy a facial, body scrub, or detox wrap at the onsite spa.
How many spa hotels are there in Greenville?
Among Expedia's 18 accommodation options in Greenville, there is 1 spa hotel.
What's there to see and do in Greenville?
Take in some sights and attractions while you're in Greenville by visiting Trop Casino Greenville, Greenville Country Club, and Harlow's Casino Resort & Spa. If you have a bit of extra time while you're in the area, you might want to check out Mississippi River and 1927 Flood Museum.
What is a Greenville spa hotel?
Spa hotels in Greenville have on-site spas and offer services such as facials and a choice of body treatments. Some also provide a selection of in-room treatments for the ultimate luxury. Spa hotels are ideal if you are looking for some R&R during your vacation.

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