Enterprise Car Rentals in St. Charles
Change your mindPenalty-free cancellation on many/select car rentals
Treat yourselfMembers save 10% or more on over 1 million car rentals
Shop smartCompare car suppliers to unlock big savings
At Expedia, we are proud to work with Enterprise due to their history of superior customer service as well their large fleet of premier vehicles. Start browsing through the great selection of rental cars by entering your search preferences into our online booking wizard and sorting through everything from spacious SUVs to compact luxury cars. Meaning, whether you need an economy car for a quick business trip or a roomy vehicle to fit the entire family on a long road trip, we’ve got you covered. And, what’s more, we always offer Enterprise St. Charles cars at the lowest possible prices. Our prices on Enterprise rentals in St. Charles can’t be beat. Get started and peruse our myriad of cheap deals and discounts on rental cars for your time in St. Charles today.
Explore a world of travel with Expedia
- Hotels near Lindenwood University
- Casino Hotels in St. Charles
- Family Hotels in St. Charles Historic District
- Hotels near Ameristar Casino St. Charles
- Resorts & Hotels with Spas in St. Charles
- Business Hotels in Maryland Heights
- St. Charles Hotels
- Family Hotels in St. Charles
- 5 Star Hotels in St. Charles
- Hotels with Bars in Bridgeton
- Hotels near Westport Plaza
- Golf Hotels in St. Charles
- Gay friendly Hotels in St. Charles
- Motel 6 Hotels in Earth City
- Hotels near Hollywood Casino Amphitheatre
- 5 Star Hotels in Bridgeton
- Casino Hotels in Earth City
- Hotels near Centene Community Ice Center
- Hotels near Kokomo Joe's Family Fun Center
- Drury Inn & Suites Hotels in Maryland Heights
- Hotels near Lambert-St. Louis Intl.
- La Quinta Inn & Suites Hotels in St. Charles
- Hotels with an Indoor Pool in Bridgeton
- Cheap Hotels in St. Charles
- Flights from Sebha (SEB) to St. Louis (STL)
- Flights from Miami (MIA) to St. Louis (STL)
- Flights from Las Vegas (LAS) to St. Louis (STL)
- Flights from Brainerd (BRD) to St. Louis (STL)
- Flights from Mianyang (MIG) to St. Louis (STL)
- Flights from Danbury (DXR) to St. Louis (STL)
- Flights from Earth City
- Flights from St. Charles
- Flights from Camiri (CAM) to St. Louis (STL)
- Flights from Pocatello (PIH) to St. Louis (STL)
- Flights from Tucuman (TUC) to St. Louis (STL)
- Flights from Aalborg (AAL) to St. Louis (STL)
- Flights from Tiko (TKC) to St. Louis (STL)
- Flights from Des Moines (DSM) to St. Louis (STL)
- Flights from Kadapa (CDP) to St. Louis (STL)
- Flights from Dayton (DAY) to St. Louis (STL)
- Flights from Edinburgh (EDI) to St. Louis (STL)
- Flights from Quincy (UIN) to St. Louis (STL)
- Flights from Bacolod (BCD) to St. Louis (STL)
- Flights from Balakovo (BWO) to St. Louis (STL)
- Flights from Saint-Tropez (LTT) to St. Louis (STL)
- Flights to Bridgeton
- Flights from Lannion (LAI) to St. Louis (STL)
- Flights from Berlin (BER) to St. Louis (STL)
- Flights from St. Peters
- Flights from French Lick (FRH) to St. Louis (STL)
- Flights from White Plains (HPN) to St. Louis (STL)
- Flights from Gaithersburg (GAI) to St. Louis (STL)
- Flights from Sukkur (SKZ) to St. Louis (STL)
- Flights from Farmington (FMN) to St. Louis (STL)
- Flights from Karachi (KHI) to St. Louis (STL)
- Dollar Rent A Car Rental Cars in Lake St Louis
- Budget Rental Cars in Valley Park
- National Car Rental Rental Cars in Lambert-St. Louis Intl.
- Fox Rental Cars Rental Cars in Cool Valley
- Alamo Rent A Car Rental Cars in O'Fallon
- Car rental Bridgeton
- Mex Rent A Car Rental Cars in Maryland Heights
- Hertz Rental Cars in Clayton
- Enterprise Rental Cars in Weldon Spring Heights
- Ace New Zealand Rental Cars in Earth City
- Enterprise Rental Cars in Lambert-St. Louis Intl.
- Thrifty Car Rental Rental Cars in Kirkwood
- Hertz Rental Cars in Berkeley
- Enterprise Rental Cars in O'Fallon
- Car rentals near Lindenwood University
- Dollar Rent A Car Rental Cars in Lambert-St. Louis Intl.
- Car rental St. Charles
- Enterprise Rental Cars in Chesterfield
- Car rentals near Fast Lane Classic Cars
- Nü Car Rentals Rental Cars in Lake St Louis
- Sixt Rental Cars in Lake St Louis
- Advantage Rent-A-Car Rental Cars in St. Charles
- Dollar Rent A Car Rental Cars in Webster Groves
- Hertz Rental Cars in St. Charles
- Sixt Rental Cars in West Alton
- Enterprise Rental Cars in Creve Coeur
- Europcar Rental Cars in Ballwin
- U-Save Rental Cars in Town and Country
- Easirent.com Rental Cars in Lake St Louis
- Ace Rental Cars in Chesterfield
- Avis Rental Cars in Lambert-St. Louis Intl.
- Avis Rental Cars in Wentzville
- Enterprise Rental Cars in Spirit of St. Louis
- First-Car Rental Cars in Lambert-St. Louis Intl.
Heading to St. Charles? Explore St. Charles with Expedia's Travel Guides to find the best hotels, vacation packages, car rental deals and more!