Top Downtown Hotels

A large lake surrounded by dense forests.

Change your mind
Book hotels with free cancellation
Treat yourself
Sign in to save 10% or more on thousands of hotels
Sign in
Be picky
Search almost a million properties worldwide

Check prices for these dates

Tonight

Tomorrow

This weekend

Next weekend

Our top choices for Downtown hotels

1. Quality Inn Seneca Clemson Area US-123

Downtown

Anthony

NT$3,273 total

includes taxes & fees

Aug 1 - Aug 2

2. Fairfield Inn & Suites Seneca Clemson Univ Area

2 km from Downtown

Ronald

NT$4,598 total

includes taxes & fees

Jul 31 - Aug 1

3. Hampton Inn & Suites Seneca-Clemson Area

2.2 km from Downtown

Daren

NT$4,215 total

includes taxes & fees

Aug 27 - Aug 28

4. Days Inn by Wyndham Seneca / Clemson Area

3.1 km from Downtown

John

NT$2,545 total

includes taxes & fees

Aug 2 - Aug 3

Standard Room, 1 King Bed, Non Smoking, Jetted Tub | Desk, laptop workspace, blackout drapes, iron/ironing board

5. Best Western Seneca-Clemson

1.7 km from Downtown

Michelle

NT$3,635 total

includes taxes & fees

Aug 1 - Aug 2

6. Tru by Hilton Seneca Clemson

8.4 km from Downtown

Jason

NT$3,757 total

includes taxes & fees

Aug 22 - Aug 23

7. Lakeside Lodge Clemson

8.6 km from Downtown

JEFFREY

NT$4,384 total

includes taxes & fees

Jul 31 - Aug 1

8. Clemson University's James F. Martin Inn

10.3 km from Downtown

Jesse

NT$5,179 total

includes taxes & fees

Jul 30 - Jul 31

9. Best Western Plus Clemson Hotel & Conference Center

11.8 km from Downtown

Steve

NT$4,235 total

includes taxes & fees

Aug 27 - Aug 28

10. The Inn at Patrick Square

15.2 km from Downtown

april

NT$5,359 total

includes taxes & fees

Jul 30 - Jul 31

11. The Shepherd Hotel Downtown Clemson

10.6 km from Downtown

Scarlett

NT$7,157 total

includes taxes & fees

Aug 2 - Aug 3

12. The Abernathy of Clemson

10.1 km from Downtown

Robert

NT$5,774 total

includes taxes & fees

Aug 24 - Aug 25

Suite, 1 King Bed with Sofa bed, Non Smoking (Efficiency) | Premium bedding, desk, laptop workspace, blackout drapes

13. Comfort Inn & Suites Clemson - University Area

11.7 km from Downtown

jose

NT$4,000 total

includes taxes & fees

Aug 9 - Aug 10

14. Inn @ Clemson

11.6 km from Downtown

Scott

NT$2,871 total

includes taxes & fees

Jul 30 - Jul 31

15. Holiday Inn Express & Suites Clemson by IHG

12.4 km from Downtown

John

NT$4,100 total

includes taxes & fees

Aug 24 - Aug 25

16. Hampton Inn Clemson-University Area

9.8 km from Downtown

Blaise

NT$3,657 total

includes taxes & fees

Aug 23 - Aug 24

17. Postcard Cabins Lake Hartwell, Outdoor Collection by Marriott Bonvoy

7.5 km from Downtown

LUIS EDUARDO

NT$4,954 total

includes taxes & fees

Aug 23 - Aug 24

18. Days Inn by Wyndham Clemson

12.5 km from Downtown

David

NT$2,710 total

includes taxes & fees

Jul 31 - Aug 1

19. Courtyard Marriott Clemson

12.9 km from Downtown

Joanna

NT$4,280 total

includes taxes & fees

Aug 2 - Aug 3

20. Rodeway Inn & Suites Walhalla

12.8 km from Downtown

michael

NT$2,531 total

includes taxes & fees

Jul 31 - Aug 1

View all properties

Where to stay in Downtown

Find the best Downtown areas and neighborhoods for the activities you enjoy most.

Serenity Bay

Though Serenity Bay might not have many top sights, you can venture to the surrounding area to see attractions like Keowee Key Golf Course and Lake Keowee.

See properties

A sunset over a calm lake with a kayaker and a large tree on the shore.

Pine Ridge Point

While Pine Ridge Point isn't home to many top sights, South Beach and Lake Keowee are some notable places to visit nearby.

See properties

Indian Oaks

While there might not be top attractions in Indian Oaks, you can explore the larger area and discover places like Keowee Reservoir and Oconee County Library Seneca Branch.

See properties

Keowee Plantation

When in Keowee Plantation, you can plan a visit to Keowee Reservoir and Oconee County Library Seneca Branch, some noteworthy sights in the nearby area.

See properties

Top Downtown Hotel Reviews

Tru by Hilton Seneca Clemson

10/10 Excellent

"Very nice stay for a short trip. Staff were very nice/helpful. Rooms were quiet and clean"

Best Western Plus Clemson Hotel & Conference Center

8/10 Good

"The staff was helpful. Good breakfast. Comforter had a stain…which was not great. Found a towel hook in bathroom on the floor in the morning because it had been put in the wall so many times the wall was coming apart. The toilet seat was coming off. I let staff know about the problems when I checked out and they appreciated it. Seemed like the room/walls need a deep cleaning/updating. However, it was still fine, quiet, and comfortable."

Frequently asked questions

What is Downtown like?

Travelers to the Downtown neighborhood in Seneca will be sure to enjoy their stay. Be sure to check out Seneca Historic District and Oconee County Library Seneca Branch as part of your Downtown travel plans.

Where is the best place to stay in Downtown?

Based on our traveler data, Quality Inn Seneca Clemson Area US-123 is one of the top choices for your stay in Downtown. This hotel offers free breakfast and free parking.

How many hotels can I expect to find in Downtown?

If you're searching for places to stay in Seneca, choose from one of Expedia's 13 hotels and other accommodations in Downtown.

If I need to cancel my hotel reservation in Downtown, will I receive a refund?

Yes! You'll find that most room reservations are fully refundable provided that you cancel before the hotel's cancellation deadline, which in most cases is within 24 or 48 hours of your arrival date. If you booked a non-refundable reservation, it may still be possible to cancel it and be given a refund within 24 hours of booking. Enter your dates, click on "Search", then you can filter by "fully refundable" to view the best deals in Downtown.

Where can I learn more about changing or cancelling my trip to Downtown?

To find more details about rescheduling or cancelling your trip to Downtown, head over to our customer service page.

What can I see and do in this Seneca neighborhood?

Seneca Historic District, Oconee County Library Seneca Branch, and Blue Ridge Arts Center are just a few attractions to check out in Downtown. As you're discovering the neighborhood, Bertha Lee Strickland Cultural Museum and The Gauntlet are some other places worth a visit. Seneca City Hall, Golden Corner Plaza, and Oconee Community Theatre are just a few of the places to visit in and around Downtown. While you're out sightseeing in Seneca, be sure to visit other sights like Applewood Shopping Center or Wyndham Plaza.

Find hotels in Downtown, Seneca

Change your mind

Treat yourself

Be picky

Check prices for these dates

Filter by

Star rating

Guest rating

Our top choices for Downtown hotels

1. Quality Inn Seneca Clemson Area US-123

2. Fairfield Inn & Suites Seneca Clemson Univ Area

3. Hampton Inn & Suites Seneca-Clemson Area

4. Days Inn by Wyndham Seneca / Clemson Area

5. Best Western Seneca-Clemson

6. Tru by Hilton Seneca Clemson

7. Lakeside Lodge Clemson

8. Clemson University's James F. Martin Inn

9. Best Western Plus Clemson Hotel & Conference Center

10. The Inn at Patrick Square

11. The Shepherd Hotel Downtown Clemson

12. The Abernathy of Clemson

13. Comfort Inn & Suites Clemson - University Area

14. Inn @ Clemson

15. Holiday Inn Express & Suites Clemson by IHG

16. Hampton Inn Clemson-University Area

17. Postcard Cabins Lake Hartwell, Outdoor Collection by Marriott Bonvoy

18. Days Inn by Wyndham Clemson

19. Courtyard Marriott Clemson

20. Rodeway Inn & Suites Walhalla

Where to stay in Downtown

Serenity Bay

Pine Ridge Point

Indian Oaks

Keowee Plantation

Top Downtown Hotel Reviews

Tru by Hilton Seneca Clemson

Frequently asked questions