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Compare 235 hotels in Cape Girardeau County with room rates, reviews, and availability. Most hotels are fully refundable.
Our top choices for Cape Girardeau County hotels

The Riverview
The Riverview
9.4 out of 10, Exceptional, (411)
The price is NT$3,218
NT$3,631 total
includes taxes & fees
Sep 14 - Sep 15

Drury Plaza Hotel Cape Girardeau Conference Center
Drury Plaza Hotel Cape Girardeau Conference Center
9.6 out of 10, Exceptional, (1009)
The price is NT$2,740
NT$3,090 total
includes taxes & fees
Sep 21 - Sep 22

Pear Tree Inn Cape Girardeau Near the Medical Center
Pear Tree Inn Cape Girardeau Near the Medical Center
9.0 out of 10, Wonderful, (1002)
The price is NT$2,131
NT$2,404 total
includes taxes & fees
Sep 17 - Sep 18

La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau
La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau
8.8 out of 10, Excellent, (612)
The price is NT$2,562
NT$2,772 total
includes taxes & fees
Sep 21 - Sep 22

Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG
Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG
9.4 out of 10, Exceptional, (1004)
The price is NT$2,892
NT$3,263 total
includes taxes & fees
Sep 21 - Sep 22

Drury Inn & Suites Cape Girardeau
Drury Inn & Suites Cape Girardeau
9.4 out of 10, Exceptional, (990)
The price is NT$2,740
NT$3,090 total
includes taxes & fees
Sep 17 - Sep 18
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Cape Girardeau County Hotel Reviews
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Top cities in Cape Girardeau County
Hotels near popular Attractions
- Hotels near Southeast Missouri State University
- Hotels near Isle Casino Cape Girardeau
- Hotels near Riverfront Bridge Park
- Hotels near Trail of Tears State Park
- Hotels near Riverfront Park
- Hotels near Cape Rock Park
- Hotels near Cape Splash Family Aquatic Center
- Hotels near Hunter Valley Winery
- Hotels near eDen Spa & Salon
- Hotels near Cape Girardeau Conservation Nature Center
Hotels near Cape Girardeau County Airports
Explore more hotels
- Drury Plaza Hotel Cape Girardeau Conference Center
- The Riverview
- Pear Tree Inn Cape Girardeau Near the Medical Center
- Pear Tree Inn Cape Girardeau West
- La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau
- Courtyard by Marriott Cape Girardeau Downtown
- Drury Inn & Suites Jackson MO
- Fairfield Inn & Suites by Marriott Cape Girardeau
- Quality Inn
- Drury Inn & Suites Cape Girardeau
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