Cape Girardeau County Vacations & Trips

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Top destinations in Cape Girardeau County

Aerial view of Jefferson City, Missouri. Jefferson City is the capital of the U.S. state of Missouri
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Jackson

Jackson

Cape Girardeau County Hotel Deals

Drury Plaza Hotel Cape Girardeau Conference Center

Drury Plaza Hotel Cape Girardeau Conference Center

3 out of 5
3351 Percy Drive Cape Girardeau MO
Fully refundableReserve now, pay when you stay
The price is NT$3,147 per night from May 18 to May 19
NT$3,147
NT$3,551 total
May 18 - May 19
includes taxes & fees
9.6/10 Exceptional! (1,007 reviews)
Loved the evening meal/drinks!

Reviewed on 2026/5/6

Drury Plaza Hotel Cape Girardeau Conference Center
The Riverview

The Riverview

4 out of 5
777 Main St Cape Girardeau MO
Fully refundableReserve now, pay when you stay
The price is NT$4,164 per night from May 11 to May 12
NT$4,164
NT$4,698 total
May 11 - May 12
includes taxes & fees
9.4/10 Exceptional! (565 reviews)
I ALWAYS stay here when I come to Cape! Wonderful, great place!

Reviewed on 2026/4/25

The Riverview
La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau

La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau

3 out of 5
3003 SOUTH OLD ORCHARD ROAD Jackson MO
Fully refundableReserve now, pay when you stay
The price is NT$3,088 per night from May 10 to May 11
NT$3,088
NT$3,342 total
May 10 - May 11
includes taxes & fees
9/10 Wonderful! (760 reviews)
Good water temperature, soft towels. Very good mattress & pillows. HVAC was quiet, effective, but unobtrusive. Breakfast was good. Only issue for me was no potatoes. Will definitely stay again.

Reviewed on 2026/5/7

La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau
See all 262 properties in Cape Girardeau County
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Frequently asked questions

How much does a Cape Girardeau County vacation package cost?
Perhaps less than you imagined — from a tempting , actually! By bundling hotels, flights and car rentals into your own customized travel package, your trip to Cape Girardeau County is just a few clicks away.
How do I get a cheap travel package to Cape Girardeau County?
Creating your own Cape Girardeau County vacation package with Expedia is one of the easiest ways to save. We have access to more than 550 air carriers and 1,000,000 properties spread across the globe. With such an awesome range to select from, you'll have no trouble creating your ideal trip.
What are the top hotels in Cape Girardeau County?
For hotels in Cape Girardeau with cozy beds and friendly service, you can't go past Drury Plaza Hotel Cape Girardeau Conference Center and Pear Tree Inn Cape Girardeau West. If you're swinging by Jackson as well, you can look forward to a relaxing night's sleep at Holiday Inn Express Hotel & Suites Cape Girardeau I-55, an IHG Hotel or Auburn Place Hotel And Suites.
How far in advance should I book my Cape Girardeau County vacation?
Reserving your spot early with Expedia means one less thing to worry about. Most carriers advertise tickets up to 12 months in advance. Generally, this is the cheapest time to book. If circumstances have left you booking late, discount tickets to Cape Girardeau County sometimes occur in the weeks leading up to departure.
What does an Expedia Cape Girardeau County travel package include?
Choose from a combination of rental cars, hotels and flights. Once you've made your booking, you can add activities and tours. Want to pick your fare class? That's also possible. The choice is all yours when it comes to planning your perfect Cape Girardeau County getaway.
What should I know before booking a Cape Girardeau County travel package?
You'll save plenty with an Expedia travel package. Combine your flights, rental cars and hotels and land exciting discounts. Hotels aren't your only option, though. We have oceanfront condos, city apartments and everything in between!
Can I choose my airline with a Cape Girardeau County Expedia vacation package?
Definitely. Expedia has more than 550 airline partners to choose from around the world. With so much choice, finding the right carrier to bring you to Cape Girardeau County will be a breeze.
If I'm not able to travel, can I cancel my Cape Girardeau County vacation package?
Yes, you can. We realize life happens, so we're here to help if you have to make changes to your Cape Girardeau County vacation package. You may be able to cancel or amend your itinerary for free if you've booked in the last 24 hours. Your airline, hotel or car rental company may charge you a fee if you booked more than 24 hours ago. Take a look at our Customer Service Portal for more information. Also, check your itinerary for the finer details on change fees.
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.