Find hotels in Depew, NY from NT$2,149

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Our top choices for Depew hotels

Comfort Inn & Suites Niagara Falls Blvd USA

Comfort Inn & Suites Niagara Falls Blvd USA
2.5 star property
La Salle
8.8 out of 10, Excellent, (1399)
"Had a very nice stay! Would stay again!"
United States
Matt
The price is NT$2,366
NT$2,697 total
includes taxes & fees
Jan 9 - 2026/1/10
Comfort Inn & Suites Niagara Falls Blvd USA

Holiday Inn Express Hotel & Suites Buffalo-Airport by IHG

Holiday Inn Express Hotel & Suites Buffalo-Airport by IHG
2.5 star property
Buffalo
8.2 out of 10, Very Good, (1007)
"The staff were exceptional, the room was beautiful and clean, the location couldn’t be beat and it was in our price range!!"
United States
Jen
The price is NT$2,987
NT$3,398 total
includes taxes & fees
Jan 5 - 2026/1/6
Holiday Inn Express Hotel & Suites Buffalo-Airport by IHG

Sleep Inn & Suites Buffalo Airport

Sleep Inn & Suites Buffalo Airport
2.5 star property
Buffalo
8.0 out of 10, Very Good, (1910)
"Clean rooms, good and fresh breakfast, location."
Canada
Felipe
The price is NT$2,249
NT$2,558 total
includes taxes & fees
Jan 19 - 2026/1/20
Sleep Inn & Suites Buffalo Airport

Buffalo Airport Hotel

Buffalo Airport Hotel
3.0 star property
Buffalo
8.0 out of 10, Very Good, (2794)
"Perfect for staying overnight !! "
United States
Lorena
The price is NT$2,308
NT$2,626 total
includes taxes & fees
Dec 26 - Dec 27
Buffalo Airport Hotel

Hampton Inn Buffalo-Airport / Galleria Mall

Hampton Inn Buffalo-Airport / Galleria Mall
2.5 star property
Buffalo
8.6 out of 10, Excellent, (1000)
"Clean room, friendly staff and great location. "
Canada
Lisa
The price is NT$3,411
NT$3,880 total
includes taxes & fees
Jan 23 - 2026/1/24
Hampton Inn Buffalo-Airport / Galleria Mall

La Quinta Inn & Suites by Wyndham Buffalo Amherst

La Quinta Inn & Suites by Wyndham Buffalo Amherst
3.0 star property
Buffalo
8.4 out of 10, Very Good, (1967)
"The hotel was great clean, accesable. quiet, close to UB"
United States
Bruce
The price is NT$2,678
NT$3,046 total
includes taxes & fees
Jan 6 - 2026/1/7
La Quinta Inn & Suites by Wyndham Buffalo Amherst

Hampton Inn Buffalo-Hamburg

Hampton Inn Buffalo-Hamburg
2.5 star property
Hamburg
9.0 out of 10, Wonderful, (1002)
"Room was very clean and staff friendly"
United States
Peter
The price is NT$3,365
NT$3,827 total
includes taxes & fees
Jan 6 - 2026/1/7
Hampton Inn Buffalo-Hamburg

Microtel Inn & Suites by Wyndham Niagara Falls

Microtel Inn & Suites by Wyndham Niagara Falls
2.5 star property
Niagara Falls
8.2 out of 10, Very Good, (1000)
"The staff friendly and the room was very clean and comfortable."
United States
Lin
The price is NT$2,269
NT$2,586 total
includes taxes & fees
Dec 29 - Dec 30
Microtel Inn & Suites by Wyndham Niagara Falls

Red Roof Inn Buffalo - Niagara Airport

Red Roof Inn Buffalo - Niagara Airport
2.0 star property
Bowmansville
7.2 out of 10, Good, (1003)
"Loved every moment, clean, well affordable and the staff were amazing "
United States
Joselyin
The price is NT$1,754
NT$1,995 total
includes taxes & fees
Jan 22 - 2026/1/23
Red Roof Inn Buffalo - Niagara Airport

DoubleTree by Hilton Hotel Buffalo - Amherst

DoubleTree by Hilton Hotel Buffalo - Amherst
4.0 star property
Buffalo
7.8 out of 10, Good, (1000)
"Everything look great we will come back again😀"
United States
Cheekeong
The price is NT$2,693
NT$3,063 total
includes taxes & fees
Jan 6 - 2026/1/7
DoubleTree by Hilton Hotel Buffalo - Amherst

Comfort Inn & Suites Buffalo Airport

Comfort Inn & Suites Buffalo Airport
3.0 star property
Buffalo
8.2 out of 10, Very Good, (1271)
"Very nice stay"
United States
James
The price is NT$3,104
NT$3,531 total
includes taxes & fees
Jan 19 - 2026/1/20
Comfort Inn & Suites Buffalo Airport

Comfort Inn & Suites Hamburg - Buffalo South

Comfort Inn & Suites Hamburg - Buffalo South
2.5 star property
Hamburg
7.4 out of 10, Good, (1002)
"I was pleasantly surprised by this hotel. It was clean, quiet, and breakfast was good."
United States
Cindy
The price is NT$2,250
NT$2,559 total
includes taxes & fees
Jan 23 - 2026/1/24
Comfort Inn & Suites Hamburg - Buffalo South

Holiday Inn Express Grand Island - Niagara Falls by IHG

Holiday Inn Express Grand Island - Niagara Falls by IHG
2.5 star property
Grand Island
8.8 out of 10, Excellent, (1622)
"Clean room, amazing staff, good amenities.. Really enjoyed our family stay there..!"
Canada
Sriprakash
The price is NT$2,330
NT$2,650 total
includes taxes & fees
Jan 4 - 2026/1/5
Holiday Inn Express Grand Island - Niagara Falls by IHG

Spark by Hilton Lockport

Spark by Hilton Lockport
3.0 star property
Lockport
7.4 out of 10, Good, (74)
"Great stay, thanks!"
Canada
Shirmilla
The price is NT$2,166
NT$2,447 total
includes taxes & fees
Jan 1 - 2026/1/2
Spark by Hilton Lockport

Hampton Inn & Suites Buffalo Downtown

Hampton Inn & Suites Buffalo Downtown
2.5 star property
Downtown Buffalo
8.8 out of 10, Excellent, (1006)
"Hotel was very clean and the staff was friendly. My room was larger than expected. Breakfast was well stocked and had good variety. Great location also!"
United States
Holly
The price is NT$4,134
NT$4,826 total
includes taxes & fees
Jan 20 - 2026/1/21
Hampton Inn & Suites Buffalo Downtown

La Quinta Inn by Wyndham Buffalo Airport

La Quinta Inn by Wyndham Buffalo Airport
3.0 star property
Buffalo
8.0 out of 10, Very Good, (1362)
"Always clean and friendly!"
Canada
Stacy
The price is NT$2,379
NT$2,706 total
includes taxes & fees
Jan 18 - 2026/1/19
La Quinta Inn by Wyndham Buffalo Airport

Hampton Inn Buffalo - Amherst, NY

Hampton Inn Buffalo - Amherst, NY
2.5 star property
Buffalo
9.4 out of 10, Exceptional, (1994)
"Great room, staff, breakfast, and pool- would definitely stay here again!"
United States
Madison
The price is NT$3,333
NT$3,791 total
includes taxes & fees
Jan 5 - 2026/1/6
Hampton Inn Buffalo - Amherst, NY

Econo Lodge Darien Lakes

Econo Lodge Darien Lakes
2.0 star property
Corfu
7.8 out of 10, Good, (804)
"Staff was really friendly!"
United States
Stephen
The price is NT$2,130
NT$2,364 total
includes taxes & fees
Jan 11 - 2026/1/12
Econo Lodge Darien Lakes

Country Inn & Suites by Radisson, Buffalo South I-90, NY

Country Inn & Suites by Radisson, Buffalo South I-90, NY
2.5 star property
Buffalo
8.2 out of 10, Very Good, (1292)
"The breakfast was very good for a free hotel breakfast. And the staff was very pleasant. "
United States
Rhonda
The price is NT$3,856
NT$4,387 total
includes taxes & fees
Jan 13 - 2026/1/14
Country Inn & Suites by Radisson, Buffalo South I-90, NY

Quality Inn Near Walden Galleria Mall

Quality Inn Near Walden Galleria Mall
2.5 star property
Buffalo
8.0 out of 10, Very Good, (1001)
"Friendly staff, easy parking"
United States
Brittany
The price is NT$2,651
NT$3,016 total
includes taxes & fees
Dec 29 - Dec 30
Quality Inn Near Walden Galleria Mall
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Depew Hotel Reviews

More cheap stays in Depew

Hotels in Depew with star-rating

Find out more about Depew

Top reasons to visit Depew

  • Family-Friendly Activities: Depew offers a variety of attractions perfect for families, including nearby amusement parks and urban parks for outdoor fun.
  • Local Shopping: Enjoy shopping at local malls and centers, providing a great experience for retail therapy.
  • Cultural Experiences: Explore the local theater scene and appreciate art at various centers, enriching your visit with culture.
  • Charming Neighborhoods: Discover friendly neighborhoods filled with budget-friendly options, making it easy to explore.
  • Convenient Location: Depew serves as a perfect base to explore the greater Buffalo area, with many nearby attractions.

Find great hotels near Depew

Depew, New York, offers a variety of lodging options to cater to every traveler’s needs. From comfortable hotels and motels to pet-friendly accommodations, you’ll find the perfect place to stay. Many hotels provide essential business services and create an inclusive atmosphere for LGBTQIA guests. Whether you're looking for the best hotels or simply searching for available options, Depew has something to make your vacation enjoyable.

  • M Hotel Buffalo: Embracing a modern and inclusive atmosphere, M Hotel Buffalo is a 3.5-star hotel that caters to business travelers and the LGBTQIA community. Situated only 4.8km from Depew, this property features contemporary design and amenities that blend comfort with functionality. Guests can enjoy a range of services including a business center, complimentary Wi-Fi, and spacious meeting rooms. The hotel's welcoming environment is perfect for those seeking a vibrant stay with a focus on diversity and support for LGBTQI travelers, making it an ideal choice for a unique vacation experience.
  • Country Inn & Suites by Radisson, Buffalo South I-90, NY: Just 9.7km from Depew, this hotel offers a cozy and inviting retreat for business travelers and pet owners alike. Country Inn & Suites by Radisson prides itself on its pet-friendly policy, allowing dogs and cats on the premises, with specific amenities to accommodate furry friends. Guests can unwind in comfortable rooms featuring complimentary breakfast, a fitness center, and a welcoming lobby with a fireplace. The hotel’s charming decor and friendly service create a warm atmosphere, making it a perfect home away from home for those traveling with pets.
  • Motel 6 Buffalo, NY - Airport - Williamsville: Located a mere 4.8km from Depew, Motel 6 offers a budget-friendly option for travelers who prioritize convenience and pet-friendliness. This no-frills motel allows pets to stay free, making it an excellent choice for those traveling with their furry companions. Guests can enjoy essential amenities such as free Wi-Fi, an outdoor pool, and 24-hour front desk service. With its straightforward accommodations and welcoming policy for pets, Motel 6 is a practical choice for travelers looking for comfort without breaking the bank.

Where to stay in Depew

Depew, New York, offers a delightful blend of family-friendly activities and charming city vibes. Explore the local neighborhoods filled with friendly people and budget-friendly options. Take a family getaway to nearby attractions featuring exquisite old mansions and parks for outdoor fun. With its convenient location, Depew serves as a perfect base to venture into the greater Buffalo area, where additional adventures and experiences await your discovery.

  • Buffalo: As a vibrant metropolis, Buffalo is a must-visit destination overflowing with culture and activities. Located adjacent to Depew, this city is known for its seasonal travel patterns, with peak visitor numbers in the summer months from June to August. Buffalo is perfect for families and outdoor enthusiasts, offering diverse experiences ranging from recreational parks to bustling shopping centers. Don't miss local landmarks such as the iconic Niagara Falls, sports stadiums, and the scenic state parks that surround the area, ensuring there's always something exciting to explore.
  • Cheektowaga: Just three miles from Depew, Cheektowaga is a charming village that offers a unique blend of family-friendly activities and business opportunities. With consistent visitor numbers, especially peaking in March to April and July, travelers are drawn to its shopping malls and educational institutions. The village is home to local highlights like state parks and sports facilities, making it an ideal spot for both leisure and business travelers. Cheektowaga's welcoming atmosphere ensures an enjoyable experience for everyone.
  • Bellevue: Located a mere two miles from Depew, Bellevue is a quaint village that boasts a rich history and a family-oriented environment. Travel to Bellevue peaks in September and around the holiday season, offering a delightful atmosphere for visitors. This village features a variety of recreational areas, shopping centers, and educational institutions. Explore its historic places and charming houses, while enjoying the lush landscapes that make Bellevue a picturesque destination for outdoor and cultural experiences alike.

Things to do near Depew

Depew, New York, is a great destination for families and outdoor enthusiasts, offering a variety of activities. Visitors can enjoy shopping at local malls and centers, have fun at nearby amusement parks, and experience the local theater scene. With its blend of family-friendly attractions and urban amenities, Depew provides a well-rounded vacation experience suited for all ages.

Shopping

In Depew, enjoy shopping at Walden Galleria Mall, just 4.8km away, featuring a mix of entertainment and family-friendly vibes. Eastern Hills Mall is also nearby at 8.0km. For a unique experience, visit Broadway Market, located 11.3km away, offering a vibrant city atmosphere.

Recreation

At Holiday Twin Rinks, enjoy ice skating surrounded by a lively atmosphere perfect for adventure and entertainment. Diamond Hawk Golf Course offers a scenic outdoor experience for golf enthusiasts, while Northtown Center at Amherst provides a vibrant sports venue for various athletic activities, just a short drive away.

Adventure

Experience the thrill of karting at Pole Position Raceway, located 4.8km from Depew, where adrenaline meets speed on an exciting track. For a scenic outdoor adventure, explore the Amherst Canalway Trail, 19.3km away, featuring beautiful landscapes perfect for hiking and biking.

If you're a winter enthusiast, the Buffalo Ski Club, situated 24.1km from Depew, offers exhilarating skiing and snowboarding opportunities amidst stunning snowy slopes.

Nightlife

In Depew, the Lancaster Opera House offers a charming evening of culture and romance just 3.2km away, while the University at Buffalo Center for the Arts provides a vibrant atmosphere for entertainment. For family fun, Lasertron, located 12.9km away, promises adventure and excitement for all ages.

*Distances are measured in a straight line; actual driving distances may vary depending on the route.

Booking tips and Expedia advantages for Depew

To save money on your trip to Depew, New York, consider visiting between January and March for lower accommodation rates. Tuesdays typically offer the best hotel deals, while Saturdays are pricier. Use Expedia to filter hotels by budget and eco-certification, and sort by price for the best options. Additionally, combining your hotel, flights, and activities into a package can lead to significant savings. Look for free activities in the area to further stretch your budget while exploring.

  • The most and least expensive months on average to stay in a hotel: The cheapest months to stay in Depew are January to March, where the prices are slightly lower. This is in comparison to July to September, where prices are slightly higher.
  • The most and least expensive days on average to stay in a hotel: The least expensive day to stay in Depew is Tuesday. The most expensive day to stay in Depew is Saturday.
  • Find cheap hotels on Expedia: Utilize Expedia’s search tool to refine your preferences, such as your budget, desired location, and hotel type. For instance, selecting the Eco-certified filter will showcase sustainable and environmentally friendly hotels that are currently available. To find the best prices and deals, simply sort the price filter from lowest to highest.
  • Consider bundling your trip: You can save money by combining your Depew hotel reservation with your flights and activities through an Expedia package.

Find the best attractions near Depew

Depew, New York, offers a delightful blend of family-friendly activities and urban experiences. Visitors can explore modern colleges and universities, relax in urban parks, and appreciate local art at various centers. The area's attractions are perfect for those seeking cultural experiences and outdoor fun, making it an ideal destination for a memorable vacation. Don't miss the nearby attractions that enhance your stay in this charming city.

  • University At Buffalo - North Campus: Experience the vibrant atmosphere of this modern university, located 12.9km from Depew. The campus features beautiful architecture and green spaces, making it a great place to stroll and soak in the academic spirit.
  • Shea's Performing Arts Center: Immerse yourself in the cultural heart of Buffalo at Shea’s, located 14.5km away. This historic venue hosts a variety of performances, from Broadway shows to concerts, showcasing the rich artistic heritage of the region.
  • Roswell Park Cancer Institute: Visit this renowned institute, just 12.9km from Depew, where cutting-edge research meets historical significance. Enjoy the serene gardens and learn about the advancements in cancer treatment while appreciating the institute's commitment to health and wellness.

Best time to go to Depew

The best time to visit Depew can depend on the weather and when visitor numbers rise and fall. The hottest average temperature in Depew falls in July, when visitor numbers are slightly high and weather is mostly sunny with light rain. The coolest average temperature in Depew falls in January, visitor numbers are average and weather is very cloudy with light rain.

calendarCalendar MonthtemperatureTemperaturerainPrecipitationmostlyCloudinessoccupationOccupancypricePricing
January25.0°F (-3.9°C)Light RainVery CloudyAverageSlightly Low
February25.9°F (-3.4°C)Light RainMostly CloudyAverageSlightly Low
March34.2°F (1.2°C)Light RainMostly CloudyAverageSlightly Low
April45.0°F (7.2°C)Light RainMostly CloudySlightly HighAverage
May57.6°F (14.2°C)Light RainMostly SunnyAverageAverage
June65.5°F (18.6°C)Light RainMostly SunnyAverageAverage
July71.1°F (21.7°C)Light RainMostly SunnySlightly HighSlightly High
August69.8°F (21.0°C)Light RainMostly SunnyAverageSlightly High
September63.5°F (17.5°C)Light RainMostly SunnySlightly HighSlightly High
October52.3°F (11.3°C)Light RainMostly CloudySlightly LowAverage
November40.5°F (4.7°C)Light RainMostly CloudySlightly LowAverage
December32.4°F (0.2°C)Light RainMostly CloudySlightly LowAverage

The nearest major airports for your trip to Depew

When planning your visit to Depew, New York, you have several airport options. Buffalo Niagara International Airport (BUF) is the closest, located 4.8km away, with nearby hotels like the 5-star Curtiss Hotel, 12.9km from BUF, and the 4-star Mosey Buffalo Williamsville, just 3.2km away. Transportation services include transfers and shuttles from these hotels. Greater Rochester International Airport (ROC) is 88.5km away, with options such as the DoubleTree by Hilton Rochester and Strathallan Rochester Hotel & Spa, both 6.4km from ROC. Niagara Falls International Airport (IAG), located 112.9km away, has accommodations like the Seneca Niagara Resort & Casino, also 9.7km from IAG.

Frequently asked questions

What's the best place for a stay in Depew?
Located 2.9 mi (4.6 km) from the heart of Depew, M Hotel Buffalo is a top choice for your stay based on our traveler data. Two other choices for your visit to the area are Hyatt Regency Buffalo / Hotel and Conference Center and Garden Place Hotel. See all available top hotels, or vacation rentals in Depew.
If I need to cancel my hotel reservation in Depew, will I receive a refund?
Yes! Most hotel bookings are fully refundable provided that you cancel before the accommodation's cancellation deadline, which is usually within 24-48 hours of your scheduled arrival. If you booked a non-refundable reservation, you might be able to cancel it and be given a refund within 24 hours of your booking. Filter your search by fully refundable to find flexible hotel deals in Depew.
Where can I learn more about changing or cancelling my trip to Depew?
For more information about picking new dates or cancelling your trip to Depew, click here.
What are some accommodations with pools in Depew?
M Hotel Buffalo: Hotel, 6-minute walk from Walden Galleria Mall. Features buffet, an indoor pool, and free self parking. Hyatt Regency Buffalo / Hotel and Conference Center and Holiday Inn Express Grand Island - Niagara Falls by IHG are a couple of other choices that feature an onsite pool. View all hotels with pools in Depew.
What's the best place to stay near Buffalo Niagara International Airport (BUF)?
Days Hotel by Wyndham Buffalo Airport is a popular 3-star hotel featuring free breakfast and a restaurant. It's located a short 0.3 mi (0.5 km) from Buffalo Niagara Intl. Airport. Other places to stay within close proximity to the airport include Hilton Garden Inn Buffalo Airport and Courtyard Buffalo Airport.
What is staying in Depew like?
Visitors can enjoy all that Depew has to offer including the shopping, restaurants, and sporting events. Tourists can also enjoy so much more including its waterfalls. In Depew, there are 12 hotels and other accommodations to choose from. Find out more about Depew.
What are the top places to visit in Depew?
Places to visit in the wider area include Holiday Twin Rinks, Walden Galleria Mall, and Samuel's Grande Manor. You'll also find Glen Falls and Buffalo Central Terminal in the area. Check out what more to see and do in Expedia's Depew guide.
How should I get around Depew?
To see more of the larger area, ride aboard one of the trains from Buffalo-Depew Station. If you want to venture out around the area, you may want a rental car in Depew for your journey.
What's the weather like in Depew?
The hottest months are usually July and August with an average temp of 67°F, while the coldest months are January and February with an average of 29°F. The snowiest months in Depew are January, March, February, and December, with each month seeing an average of 17 inches of snowfall.

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