A sunset over a calm lake with tall trees reflected in the water.

Find Resorts & Hotels with Spas in Charleston, MO

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Check availability on Charleston Resorts & Hotels with Spas

Tonight
Oct 3 - Oct 4
Tomorrow
Oct 4 - Oct 5
Next weekend
Oct 9 - Oct 11
In two weeks
Oct 16 - Oct 18
No exact matches found, but these alternatives could be just right

Recommended hotels in Charleston

A hotel room with a large bed, two bedside lamps, a framed picture of a bridge, and a wooden nightstand with a phone.
A reception area with a sofa, a coffee table, a potted plant, and a framed picture on the wall.
A shower area with a bathtub, a towel rack, and a grab bar.
A restaurant with wooden cabinets, a refrigerator, and a counter with various items. There are tables and chairs for dining.

1. Super 8 by Wyndham Charleston/Sikeston East MO

Super 8 by Wyndham Charleston/Sikeston East MO
Charleston
NT$1,896
NT$2,104 total
includes taxes & fees
Oct 26 - Oct 27
Super 8 by Wyndham Charleston/Sikeston East MO
A building with a fountain and flower beds in front.
A hotel room with a large bed, two bedside tables with lamps, a chair, a small table, and a picture on the wall.
A modern kitchen with dark wooden cabinets, a central island, and a ceiling fan.
A hotel room with a beige sofa, two patterned armchairs, a ceiling fan, a flat-screen TV, and a window with curtains.

2. The Riverstone Hotel Charleston-Sikeston

The Riverstone Hotel Charleston-Sikeston
Charleston
NT$2,118
NT$2,351 total
includes taxes & fees
Oct 16 - Oct 17
The Riverstone Hotel Charleston-Sikeston
A hotel room with a large bed, a desk, a television, and a bathroom visible through an open door.
A bathroom with a sink, mirror, towel rack, shower, and toilet.
A hotel room with two beds, a nightstand, a lamp, and a window with curtains.
A kitchen with wooden cabinets, a granite countertop, a built-in microwave, and a window with a view.

3. Eagle Inn Charleston

Eagle Inn Charleston
Charleston
NT$2,103
NT$2,333 total
includes taxes & fees
Oct 6 - Oct 7
Eagle Inn Charleston
An indoor swimming pool with a 3 FT depth marker, a metal ladder, and a tiled floor.
A spacious lobby with a polished floor, seating areas, and modern lighting fixtures.
An outdoor seating area with sofas and planters, surrounded by a building with large windows and a brick wall.
A spacious dining area with high tables and chairs, a bar counter, and large windows providing natural light.

4. Drury Inn & Suites Sikeston, MO

Drury Inn & Suites Sikeston, MO
Sikeston
NT$2,995
NT$3,443 total
includes taxes & fees
Oct 29 - Oct 30
Drury Inn & Suites Sikeston, MO
A Hampton Inn with a stone facade, outdoor seating area, and a fire pit.
A conference room with a large rectangular table, six chairs with patterned upholstery, two modern ceiling lights, a bowl of fruit on the table, and large windows with curtains.
A Hampton Inn hotel with a modern facade, a stone entrance, and a well-lit entrance area.
A hotel lobby with a bar area, seating arrangements, and a large window providing natural light.

5. Hampton Inn Sikeston

Hampton Inn Sikeston
Sikeston
NT$3,358
NT$3,819 total
includes taxes & fees
Oct 18 - Oct 19
Hampton Inn Sikeston
A hotel lobby with a central bar area, multiple dining tables and chairs, large windows, and a patterned carpet.
Room
An indoor swimming pool with clear water, surrounded by lounge chairs and tables, and large windows providing natural light.
A hotel with a covered entrance, a sign indicating a restaurant, and a well-lit parking area.

6. Best Western Plus Sikeston I-55

Best Western Plus Sikeston I-55
Sikeston
NT$2,701
NT$3,079 total
includes taxes & fees
Nov 1 - Nov 2
Best Western Plus Sikeston I-55
An outdoor seating area with a circular fire pit surrounded by chairs, a covered patio, and a building with large windows in the background.
A modern indoor swimming pool with clear glass walls, a tiled deck, and multiple lounge chairs.
A modern lobby with a green sofa, two armchairs, a wooden coffee table, and a patterned rug.
A modern hotel building with a sign reading "TOWNPLACE SUITES BY MARRIOTT" and "Fairfield BY MARRIOTT".

7. Fairfield Inn & Suites by Marriott Sikeston

Fairfield Inn & Suites by Marriott Sikeston
Sikeston
NT$3,218
NT$3,644 total
includes taxes & fees
Nov 1 - Nov 2
Fairfield Inn & Suites by Marriott Sikeston
A hotel room with a large bed, a desk with a computer, a chair, a window with a view, and a wall-mounted TV.
A living room with a sofa, two chairs, a coffee table, a television, and a window with blinds.
A reception area with a sign for 'Travel Inn and Suites' and a counter with a computer and a phone.
A bathroom with a glass shower door, a white toilet, and a towel rack with folded towels.

8. Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67)

Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67)
Sikeston
NT$2,214
NT$2,523 total
includes taxes & fees
Oct 26 - Oct 27
Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67)
Property amenity
A modern hotel with a sign reading "Towneplace Suites by Marriott Fairfield." It features a flat roof, large windows, and a well-lit entrance.
A modern hotel room with a large window, a gray sofa, a small round table, a white chair, and a bed.
An outdoor bar area with a modern design, featuring a counter, bar stools, and a seating area with chairs.

9. TownePlace Suites by Marriott Sikeston

TownePlace Suites by Marriott Sikeston
Sikeston
NT$3,361
NT$3,806 total
includes taxes & fees
Oct 18 - Oct 19
TownePlace Suites by Marriott Sikeston
A modern hotel room with a large bed, a smaller bed, a desk, and a chair. There is a window with curtains and a painting on the wall.
A spacious lobby with a central atrium, a piano, and a reception desk.
Lobby
A bathroom with a bathtub, a sink, and a mirror.

10. Days Inn and Suites by Wyndham Sikeston

Days Inn and Suites by Wyndham Sikeston
Sikeston
NT$2,112
NT$2,408 total
includes taxes & fees
Nov 1 - Nov 2
Days Inn and Suites by Wyndham Sikeston
View all properties

Choose what matters most at spa hotels in Charleston

Pool
Breakfast included
Hot tub
4 stars
5 stars

Top Charleston Hotel Reviews

Drury Inn & Suites Cape Girardeau

Drury Inn & Suites Cape Girardeau

10/10 Excellent
"EVERYONE was EXTREMELY FRIENDLY even maintenance all FRIENDLY"
Rex 1-night trip
Posted 1 day ago
Drury Inn & Suites Cape Girardeau
Eagle Inn Charleston

Eagle Inn Charleston

10/10 Excellent
"Great"
Jackson 1-night trip
Posted 6 months ago
Eagle Inn Charleston

Frequently asked questions

Looking for a spa hotel in Charleston?
Treat yourself to some time in a luxurious spa hotel and you won't regret it. Check out the opera and restaurants in Charleston—your day trip starts here. Be sure to pay a visit to the churches during your stay. Hotels with spas are the perfect way to break out of your routine and add a layer of luxury to your vacation.
What's there to see and do in Charleston?
Experience all that Charleston has to offer when you visit Mississippi River, Ohio River, and Ballard Wildlife Management Area. If you have a bit of extra time while you're in the area, you might want to check out Columbus-Belmont State Park and Big Oak Tree State Park.
What is a Charleston spa hotel?
Spa hotels in Charleston provide lodging and have an on-site spa offering services like facials and body treatments. Some also offer in-room treatments. Spa hotels are great for rest, rejuvenation, and relaxation.

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