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Find Luxury Hotels in Cape Girardeau, MO

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Check availability on Cape Girardeau Luxury Hotels

Tonight
Jul 19 - Jul 20
Tomorrow
Jul 20 - Jul 21
Next weekend
Jul 25 - Jul 27
In two weeks
Aug 1 - Aug 3

Top Cape Girardeau Luxury Hotels

Pear Tree Inn Cape Girardeau Near the Medical Center
Lobby

Pear Tree Inn Cape Girardeau Near the Medical Center

2.5 star property
9.0 out of 10, Wonderful, (1004)
"Excellent place to stay "
The price is NT$2,057
NT$2,321 total
includes taxes & fees
Jul 21 - Jul 22
Pear Tree Inn Cape Girardeau Near the Medical Center
Quality Inn
Lobby

Quality Inn

2.5 star property
7.0 out of 10, Good, (611)
"Great room, great experience "
The price is NT$1,969
NT$2,222 total
includes taxes & fees
Jul 20 - Jul 21
Quality Inn
Drury Inn & Suites Cape Girardeau
Business center

Drury Inn & Suites Cape Girardeau

3.0 star property
9.4 out of 10, Exceptional, (958)
"Room was very clean and staff was excellent!"
The price is NT$2,645
NT$2,983 total
includes taxes & fees
Jul 25 - Jul 26
Drury Inn & Suites Cape Girardeau
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Frequently asked questions

Are you searching for the perfect hotel for your luxury getaway to Cape Girardeau?
Use Expedia to arrange your flight to Cape Girardeau, MO (CGI-Cape Girardeau Municipal) airport or Cairo, IL (CIR-Cairo Regional) airport, and then select from a variety of places to stay that will deliver the luxury you want. Amenities are important when you plan a vacation, so we make it easy to get what you'd like to make your stay relaxing and comfortable. If you want an upscale hotel that has fine dining, a spa, or several swimming pools, Expedia can help you find the best luxury hotel experience that Cape Girardeau offers. During your visit, you might want to enjoy the university which Cape Girardeau is known for.
How many luxury hotels will I find in Cape Girardeau?
Lie in the lap of luxury during your getaway to Cape Girardeau in one of Expedia's 6 luxury hotels.
When can I expect good weather in Cape Girardeau?
Planning for the weather is an important factor for making your trip to Cape Girardeau a success, especially when you're splurging. The hottest months are usually July and August with an average temp of 76°F, while the coldest months are January and February with an average of 40°F. Average annual precipitation for Cape Girardeau is 59 inches.
What's there to see and do in Cape Girardeau?
Enjoy all that Cape Girardeau has to offer and visit Isle Casino Cape Girardeau, Show Me Center, and Cape Splash Family Aquatic Center. If you have a bit of extra time while you're in the area, you might want to check out Hunter Valley Winery and Trail of Tears State Park.