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Find All South Carolina Midlands Hotels
We have found 2942 South Carolina Midlands Hotels
- Quality Inn & Suites Columbia Harbison
- Tru by Hilton Rock Hill
- Hilton Garden Inn Columbia Downtown, SC
- Best Western Inn
- Quality Inn & Suites Lexington
- The Inn at the Crossroads
- Hyatt Place Sumter / Downtown
- Courtyard by Marriott Ballantyne
- Sleep Inn & Suites
- Aloft Florence
- Comfort Inn Blythewood - North Columbia
- Hampton Inn & Suites Lexington Columbia
- Towneplace Suites Columbia Northwest/Harbison
- Tru by Hilton Florence I-95
- Best Western Carowinds
- Sleep Inn Airport
- Quality Inn & Suites
- Aloft Columbia Harbison
- MainStay Suites Columbia Harbison
- Days Inn by Wyndham Rock Hill
- Wingate by Wyndham Columbia/Fort Jackson
- Holiday Inn Express & Suites Columbia Downtown - The Vista by IHG
- Delta Hotels by Marriott Columbia Northeast
- Courtyard by Marriott Charlotte Fort Mill, SC
- Baymont by Wyndham Columbia Northwest
- Comfort Suites Florence I-95
- Econo Lodge
- Holiday Inn Rock Hill by IHG
- Motel 6 Fort Mill, SC - Charlotte
- Hampton Inn Columbia-Downtown Historic District
- Days Inn by Wyndham Orangeburg
- Holiday Inn & Suites Columbia NE - Ft Jackson Area by IHG
- Courtyard by Marriott Columbia Cayce
- Clarion Inn Columbia Airport
- Tru by Hilton Sumter
- Best Western Rock Hill
- Wingate by Wyndham Columbia / Lexington
- Holiday Inn Express & Suites Newberry by IHG
- Holiday Inn Santee by IHG
- Staybridge Suites Florence - Civic Center by IHG
- Hawthorn Extended Stay By Wyndham Columbia / Ft. Jackson
- Holiday Inn Express Hotel & Suites Camden-I20 (Hwy 521) by IHG
- Hampton Inn & Suites Florence-North-I-95
- Cambria Hotel Rock Hill - University Center
- Comfort Inn & Suites
- Howard Johnson by Wyndham Rock Hill
- SureStay Hotel by Best Western Manning
- Holiday Inn Express & Suites Florence I-95 & I-20 Civic Ctr by IHG
- Clarion Hotel Fort Mill Near Amusement Park
- Hampton Inn Santee-I-95
- Holiday Inn Express & Suites Columbia-I-20 @ Clemson Rd by IHG
- Comfort Inn Columbia West
- Super 8 by Wyndham Florence
- SpringHill Suites by Marriott Orangeburg
- Extended Stay America Select Suites Columbia Ft. Jackson
- Microtel Inn & Suites by Wyndham Columbia/At Fort Jackson
- Best Western Executive Inn & Suites
- Fairfield Inn by Marriott Hartsville
- Home2 Suites by Hilton Columbia Downtown
- Staybridge Suites Rock Hill by IHG
- Ramada Limited Columbia
- Holiday Inn Express & Suites Aiken by IHG
- TRU BY Hilton North Augusta
- Candlewood Suites, Columbia/Ft. Jackson by IHG
- Holiday Inn Express Hotel & Suites Blythewood by IHG
- Towneplace Suites by Marriott Aiken Whiskey Road
- Garner Hotel Aiken South by IHG
- Microtel Inn & Suites by Wyndham Columbia/Fort Jackson N
- Comfort Inn & Suites Ft. Jackson Maingate
- Comfort INN AND Suites
- Super 8 by Wyndham Columbia SC / Ft. Jackson
- Tru By Hilton Fort Mill, SC
- Hilton Garden Inn Columbia Northeast
- Motel 6 Florence, SC
- Days Inn By Wyndham Lexington/Columbia
- Baymont by Wyndham Orangeburg North
- Comfort Suites Rock Hill Manchester Meadows Area
- Fairfield Inn by Marriott Orangeburg
- Red Roof Inn Florence - Civic Center
- Home2 Suites by Hilton Columbia Harbison
- Baymont by Wyndham Cheraw
- Microtel Inn & Suites by Wyndham Rock Hill/Charlotte Area
- Hampton Inn Manning
- Courtyard by Marriott Rock Hill
- Extended Stay America Suites Rock Hill
- Home2 Suites by Hilton Rock Hill
- Homewood Suites By Hilton Columbia Downtown
- Motel 6 Rock Hill, SC
- Hampton Inn & Suites Fort Mill
- Best Western Executive Inn
- Holiday Inn Express & Suites Latta by IHG
- Fairfield Inn & Suites by Marriott Florence I-20
- Clarion Inn & Suites
- SpringHill Suites by Marriott Florence
- Holiday Inn Express North Augusta by IHG
- Comfort Inn & Suites Santee
- Sleep Inn Florence North
- Fairfield Inn & Suites by Marriott Aiken
- Clarion Inn & Suites Aiken South
Let Expedia take you to the best Hotels in South Carolina Midlands. You'll find the largest selection of hotel deals, discount prices, and cheap hotel rates on reservations anywhere in the world. Expedia, the leader in world travel, gives you customer reviews, maps, and the best selection of hotels near landmarks and attractions.
