Prague City Center 5 Stars Hotels

Start date: Check-in selected.
To Date
End date: Check-out
  • Change your mind

    Book hotels with free cancellation
  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
  • Be picky

    Search almost a million properties worldwide

Check availability on Prague City Center 5 Star Hotels

This weekend
Next weekend

Our top choices for Prague City Center 5-star hotels

Michelangelo Grand Hotel Prague

Michelangelo Grand Hotel Prague
5.0 star property
Prague City Center
9.4 out of 10, Exceptional, (3169)
"Great room, comfy bed, great breakfast, location excellent "
United Kingdom
Carol
The price is NT$3,476
NT$4,046 total
includes taxes & fees
Jan 18 - 2026/1/19
Michelangelo Grand Hotel Prague

Almanac X Alcron Prague

Almanac X Alcron Prague
5.0 star property
Prague City Center
9.6 out of 10, Exceptional, (837)
"Upscale hotel, conveniently located in old town. Great breakfast buffet and other amenities."
United States
Christian
The price is NT$4,518
NT$5,208 total
includes taxes & fees
Jan 26 - 2026/1/27
Almanac X Alcron Prague

Grandior Hotel Prague

Grandior Hotel Prague
5.0 star property
Prague City Center
9.0 out of 10, Wonderful, (1203)
"Clean, great staff and great service. "
United States
Ben
The price is NT$2,633
NT$3,101 total
includes taxes & fees
Jan 11 - 2026/1/12
Grandior Hotel Prague

Grandium Hotel Prague

Grandium Hotel Prague
5.0 star property
Prague City Center
9.2 out of 10, Wonderful, (1100)
"Great rooms, friendly staff, wonderful breakfast"
United States
Toni
The price is NT$2,805
NT$3,295 total
includes taxes & fees
Jan 25 - 2026/1/26
Grandium Hotel Prague

Four Seasons Hotel Prague

Four Seasons Hotel Prague
5.0 star property
Prague City Center
9.6 out of 10, Exceptional, (618)
"Best hotel in Prague"
United States
Hakan
The price is NT$21,380
NT$24,093 total
includes taxes & fees
Jan 6 - 2026/1/7
Four Seasons Hotel Prague

ANDAZ PRAGUE, BY HYATT

ANDAZ PRAGUE, BY HYATT
5.0 star property
Prague City Center
9.6 out of 10, Exceptional, (174)
"Amazing hotel and gorgeous room, great location "
United States
Daniel H
The price is NT$8,147
NT$9,276 total
includes taxes & fees
Jan 5 - 2026/1/6
ANDAZ PRAGUE, BY HYATT

Iron Gate Hotel & Suites Prague by BHG

Iron Gate Hotel & Suites Prague by BHG
5.0 star property
Prague City Center
9.2 out of 10, Wonderful, (1002)
"Beautiful rustic hotel in an excellent location"
United States
Paula
The price is NT$2,791
NT$3,279 total
includes taxes & fees
Jan 18 - 2026/1/19
Iron Gate Hotel & Suites Prague by BHG

Kosher Hotel KING DAVID Prague

Kosher Hotel KING DAVID Prague
5.0 star property
Prague City Center
8.2 out of 10, Very Good, (924)
"Lovely spacious rooms, great food. "
United States
Adena
The price is NT$5,628
NT$6,455 total
includes taxes & fees
Jan 29 - 2026/1/30
Kosher Hotel KING DAVID Prague

Grand Hotel Bohemia

Grand Hotel Bohemia
5.0 star property
Prague City Center
9.6 out of 10, Exceptional, (1008)
"The room was clean, the staff were helpful, and the breakfast was wonderful. "
United States
Kenneth Raymond
The price is NT$4,203
NT$4,857 total
includes taxes & fees
Jan 14 - 2026/1/15
Grand Hotel Bohemia

Falkensteiner Hotel Prague

Falkensteiner Hotel Prague
5.0 star property
Prague City Center
9.6 out of 10, Exceptional, (433)
"Awesome hotel"
United States
Todd
The price is NT$4,507
NT$5,198 total
includes taxes & fees
Jan 19 - 2026/1/20
Falkensteiner Hotel Prague

Prague Marriott Hotel

Prague Marriott Hotel
5.0 star property
Prague City Center
9.0 out of 10, Wonderful, (1000)
"Fantastic stay experience "
Canada
Yitao
The price is NT$5,825
NT$6,676 total
includes taxes & fees
Jan 9 - 2026/1/10
Prague Marriott Hotel

Cosmopolitan Hotel Prague

Cosmopolitan Hotel Prague
5.0 star property
Prague City Center
9.6 out of 10, Exceptional, (1066)
"Great location and fantastic hotel "
United Kingdom
David
The price is NT$3,699
NT$4,295 total
includes taxes & fees
Jan 18 - 2026/1/19
Cosmopolitan Hotel Prague

Hotel Kings Court

Hotel Kings Court
5.0 star property
Prague City Center
9.4 out of 10, Exceptional, (1003)
"Amazing hotel and friendly staff "
Canada
Claire
Hotel Kings Court

The Grand Mark Prague - The Leading Hotels of the World

The Grand Mark Prague - The Leading Hotels of the World
5.0 star property
Prague City Center
9.4 out of 10, Exceptional, (743)
"Amazing Hotel with a amazing Service "
United States
Romeo
The price is NT$10,697
NT$11,981 total
includes taxes & fees
Jan 11 - 2026/1/12
The Grand Mark Prague - The Leading Hotels of the World

Hilton Prague Old Town

Hilton Prague Old Town
5.0 star property
Prague City Center
8.8 out of 10, Excellent, (1000)
"Lovely hotel"
United Kingdom
ira
The price is NT$4,652
NT$5,361 total
includes taxes & fees
Jan 11 - 2026/1/12
Hilton Prague Old Town

The Mozart Prague by Accor

The Mozart Prague by Accor
5.0 star property
Prague City Center
9.2 out of 10, Wonderful, (1001)
"Clean room, great location, staff was attentive and responsive. "
United States
Cheryl
The price is NT$6,665
NT$7,615 total
includes taxes & fees
Jan 11 - 2026/1/12
The Mozart Prague by Accor

Eurostars Thalia

Eurostars Thalia
5.0 star property
Prague City Center
8.8 out of 10, Excellent, (727)
"The location is excellent. The service was really good as well. The bathroom was really big and they have a breakfast but 20 euro seemed steep. Plenty of shopping all around! I would stay here again. "
United States
Ann
The price is NT$1,807
NT$2,175 total
includes taxes & fees
Jan 14 - 2026/1/15
Eurostars Thalia

Art Deco Imperial Hotel

Art Deco Imperial Hotel
5.0 star property
Prague City Center
9.6 out of 10, Exceptional, (1001)
"Wonderful and decent breakfast. "
United States
lucilyn
The price is NT$3,847
NT$4,461 total
includes taxes & fees
Jan 20 - 2026/1/21
Art Deco Imperial Hotel

The Emblem Prague Hotel - Preferred Hotels & Resorts

The Emblem Prague Hotel - Preferred Hotels & Resorts
5.0 star property
Prague City Center
9.4 out of 10, Exceptional, (1001)
"Ideal location for exploring Prague Old Town, Christmas Market and other sights."
United States
Mika
The price is NT$6,140
NT$7,029 total
includes taxes & fees
Jan 4 - 2026/1/5
The Emblem Prague Hotel - Preferred Hotels & Resorts

Ambassador Zlatá husa

Ambassador Zlatá husa
5.0 star property
Prague City Center
8.2 out of 10, Very Good, (755)
"This hotel is lovely, perfect location. All the attractions restaurants bars are all in walking distance, would definitely stay here again ."
United Kingdom
Catherine
The price is NT$3,452
NT$4,019 total
includes taxes & fees
Jan 25 - 2026/1/26
Ambassador Zlatá husa
Save an average of 15% on thousands of hotels when you're signed in

Explore similar 4-star hotels

Many 4-star hotels have the same amenities as 5-star hotels. See all 4-star hotels in Prague City Center.
Still don't see what you're looking for?
See all properties in Prague City Center.
You can also use these popular filters to refine your search.
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Top Prague City Center Hotel Reviews

Frequently asked questions

How much does it cost to stay in a 5-star hotel in Prague City Center?
The amount you pay for a 5-star hotel in Prague City Center can vary according to when you decide to travel and how long you plan to be away, among a number of factors. Take advantage of our price per night filter and other search tools to land the best rate on a luxurious stay.

  • Search for the lowest price per night from NT$2,555

What makes a hotel 5 stars in Prague City Center?
From gourmet dining venues and 24-hour gyms to swimming pools and deluxe bedding, the 5-star experience in Prague City Center is all about comfort and indulgence. But it calls for more than just top-notch amenities to receive a 5-star rating. Accommodations also have to offer extraordinary services like in-room massages, dry cleaning and laundry and 24-hour room service.
Are there any 5-star all-inclusive resorts in Prague City Center?
Our filters are the quickest way to narrow down what you're looking for. Select "5-star" and "All inclusive" to show the finest properties in Prague City Center where your lodging, meals, activities and entertainment are included in the upfront price. At these retreats, your vacation is pure relaxation and indulgence from the moment you arrive.