Independent South Carolina Midlands hotels
Plan, book, stay with confidence
Be picky
Search almost a million properties worldwide
Change your mind
Book hotels with free cancellation
Check South Carolina Midlands hotel availability
Compare rooms and suites by Independent in South Carolina Midlands with rates, reviews, and availability. Most hotels are fully refundable.
Hotel Trundle
Hotel Trundle
9.8 out of 10, Exceptional, (694)
The price is NT$6,371
per night
Jun 16 - Jun 17
stayAPT Suites Columbia-Irmo Harbison
stayAPT Suites Columbia-Irmo Harbison
8.8 out of 10, Excellent, (214)
The price is NT$3,346
per night
May 30 - May 31
Save an average of 15% on thousands of hotels when you're signed in
The Inn at the Crossroads
The Inn at the Crossroads
9.4 out of 10, Exceptional, (583)
The price is NT$5,011
per night
Jun 9 - Jun 10
stayAPT Suites Rock Hill
stayAPT Suites Rock Hill
8.6 out of 10, Excellent, (137)
The price is NT$3,331
per night
Jun 3 - Jun 4
Carriage House Inn
Carriage House Inn
9.6 out of 10, Exceptional, (377)
The price is NT$6,403
per night
Jun 2 - Jun 3
Royal Regency Inn
Royal Regency Inn
7.6 out of 10, Good, (18)
The price is NT$1,650
per night
Jun 6 - Jun 7
Florence Express Inn
Florence Express Inn
6.0 out of 10, (272)
The price is NT$1,724
per night
May 30 - May 31
Affordable Suites Florence
Affordable Suites Florence
9.2 out of 10, Wonderful, (50)
The price is NT$2,098
per night
Jun 1 - Jun 2
Budget Inn Timmonsville
Budget Inn Timmonsville
7.0 out of 10, Good, (279)
The price is NT$1,769
per night
May 30 - May 31
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Recent reviews of South Carolina Midlands hotelsExpedia verified reviews
5/5 Excellent
"Had a ball "
A verified traveler stayed at Hilton Garden Inn Columbia/Harbison
Posted 15 hours ago
South Carolina Midlands Hotels by Brand
Hotels in South Carolina Midlands Neighborhoods
Hotels near popular South Carolina Midlands Attractions
- Hotels near Carowinds Theme Park
- Hotels near Fort Jackson
- Hotels near University of South Carolina
- Hotels near Riverbanks Zoo and Garden
- Hotels near Williams Brice Stadium
- Hotels near Congaree National Park
- Hotels near Rock Hill Sports & Event Center
- Hotels near Florence Civic Center
- Hotels near Village at Sandhill Mall
- Hotels near Lake Marion
More Hotel Options in South Carolina Midlands
- Adventure Hotels (88)
- Beach Hotels (42)
- Boutique Hotels (10)
- Business Hotels (268)
- Casinos (1)
- Cheap Hotels (136)
- Family Hotels (292)
- Golf Hotels (148)
- Green Hotels (1)
- Historic Hotels (153)
- Hotel Wedding Venues (47)
- Hotel with a Concierge (23)
- Hotels with Bars (112)
- Hotels with Early Check-in (2)
- Hotels with Free Parking (322)
- Hotels with Hot Tubs (67)
- Hotels with WiFi (338)
- Hotels with a Pool (258)
- Hotels with an Indoor Pool (52)
- Hotels with smoking rooms (42)
- Luxury Hotels (83)
- Pet-friendly Hotels (190)
- Resorts & Hotels with Spas (51)
- Romantic Hotels (30)
- Shopping Hotels (226)
Explore more hotels
- La Quinta Inn & Suites by Wyndham Florence
- Lexington Inn and Suites
- Hyatt Place Florence Downtown
- Country Inn & Suites by Radisson, Columbia, SC
- Tru By Hilton Columbia Greystone
- Hyatt Place Columbia/Downtown/The Vista
- Baymont by Wyndham Santee
- Marriott Columbia
- Wingate by Wyndham Columbia / Lexington
- Hyatt Place Columbia/Harbison
- Hampton Inn Columbia I-26/Harbison Blvd.
- Hampton Inn & Suites Columbia Killian Road
- Sheraton Columbia Downtown Hotel
- Clarion Pointe Near University
- Country Inn & Suites by Radisson, Aiken, SC
- Days Inn by Wyndham Rock Hill
- La Quinta Inn & Suites by Wyndham Rock Hill
- Hilton Garden Inn Columbia Airport
- Hyatt Place Sumter / Downtown
Expedia's Latest Trends
Hotels
Flights
Packages
General
Visit Bay AreaVisit KauaiVisit Upstate New YorkVisit Little Diomede IslandVisit Bainbridge IslandVisit Fire IslandVisit Hawaii IslandVisit Upstate South CarolinaVisit Puget SoundVisit Long IslandVisit PumpkintownVisit OahuVisit Northeast GeorgiaVisit Silicon ValleyVisit Cannonborough ElliotboroughVisit Finger Lakes RegionVisit Outer BanksVisit White Mountains