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Yes, you can find vacation rentals in Des Moines close to Science Center of Iowa, or you can choose a secluded option if you're looking for extra privacy while you relax. Travelers who like culture and the arts give Des Moines high marks for its acclaimed theater scene and lively festivals. Leave some time to check out the great live music and top-notch restaurants during your visit.

With 233 Expedia vacation rentals, you're sure to find just the right place for your Des Moines stay.

Enjoy the outdoors at Greater Des Moines Botanical Garden and Gray’s Lake Park, or simply take in cultural attractions like Science Center of Iowa and Hoyt Sherman Place. Des Moines Civic Center and Hy Vee Hall are other places to visit while you're in town.

A vacation rental is a private property where you can stay for a few weeks or just a few days in Des Moines. Vacation rentals offer extras such as patios, hot tubs, and fire pits so you'll have all the conveniences of home. If you're concerned about cleanliness, vacation rentals can offer a sense of privacy away from shared hotel elevators and busy lobbies while still allowing you the excitement and enjoyment of travel. You'll also get more space in a vacation rental than in a standard hotel, which makes a vacation rental an attractive choice for small groups.