Plan, book, travel with confidence
Better together
Save up to NT$25,000 when you book a flight and hotel together*
Find the right fit
With over 300,000 hotels worldwide, it's easy to create a perfect package
Rest easy
Plan, book, and manage your trip all in one place

Top Pet-friendly Eastern South Dakota Hotels

La Quinta Inn & Suites by Wyndham Sioux Falls

4521 W. 41st Street Sioux Falls SD

9 min drive from Denny Sanford Premier Center

Dogs and cats may join you (for a fee) during your stay at this pet-friendly hotel. Take the opportunity to stretch your legs on the nearby hiking or biking ...

9.2/10 Wonderful! (1,564 reviews)

Clean Quiet

Reviewed on 2026/5/10

Econo Lodge Sioux Falls Empire Mall

3500 Gateway Boulevard Sioux Falls SD

9 min drive from Denny Sanford Premier Center

This pet-friendly hotel welcomes dogs and cats (fees apply).

7/10 Good! (442 reviews)

Economy hotel, no thrills, but it's nice

Staff was really nice. Rooms are spacious. Good value and convenient to many stores/restaurants, etc. Rooms for clean.

Reviewed on 2022/10/18

Kelly Inn & Suites Mitchell South Dakota

1010 Cabela Drive Mitchell SD

3 hours drive from Denny Sanford Premier Center

This pet-friendly hotel welcomes dogs for free.

8/10 Very Good! (1,095 reviews)

There was trash under the bed. There was litter all over the carpet the tub had a soap scum ring and would not drain. None of us could shower. The staff was not helpful at all. You had to wait at the service desk forever to get waited on.

Reviewed on 2026/5/11

See all 945 properties in Eastern South Dakota

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.