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Top Luxury Southeastern Indiana Hotels

21c Museum Hotel Louisville

700 W Main Street Louisville KY

9 min walk from KFC Yum Center

21c Museum Hotel Louisville is one of the Louisville luxury 4.5-star boutique properties where you can treat yourself to Champagne service, massage services, ...

9.4/10 Exceptional! (1,000 reviews)

21c in Louisville is always awesome. The property is well appointed and attractive. The staff is friendly, helpful and welcoming. The food is first rate and there is always so much to look at. It’s my favorite hotel in Louisville.

Reviewed on 2026/4/27

West Baden Springs Hotel

8538 W Baden Ave West Baden Springs IN

2 hours drive from KFC Yum Center

Treat yourself to a luxury stay at West Baden Springs Hotel, where you can enjoy amenities like plush bedding, designer toiletries, and more. Deluxe amenities ...

The Brown Hotel

335 W Broadway Louisville KY

14 min walk from KFC Yum Center

The Brown Hotel is a Louisville luxury 4.5-star boutique property where you can pamper yourself with Egyptian cotton sheets, plush bedding, and more. The restaurant, ...

9.4/10 Exceptional! (1,179 reviews)

We loved our stay at The Brown Hotel! Charming older hotel. Restaurant/bars were wonderful, staff was very friendly and helpful, room was clean and comfortable. Location was a little away from 4th St and Whiskey Row, but easy 1 mile walk to attractions. Highly recommend The Brown Hotel!

Reviewed on 2026/4/28

See all 1,156 properties in Southeastern Indiana

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.