Eastern South Dakota Luxury Vacations 2026

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Top Luxury Eastern South Dakota Hotels

Baymont by Wyndham Sioux Falls West (67058) Sioux/ Near Airport

3101 W Russell St Sioux Falls SD

25 min walk from Denny Sanford Premier Center

Be treated to luxurious accommodations at Baymont by Wyndham Sioux Falls West (67058) Sioux/ Near Airport, where you can enjoy amenities like hydromassage showers, ...

7/10 Good! (1,005 reviews)

"Room and hotel need general maintenance done. I’d look elsewhere as can probably get a better room for same price. They also tried to charge me a $50 deposit for any damages."

Reviewed on 2026/8/23

Econo Lodge Sioux Falls Empire Mall

3500 Gateway Boulevard Sioux Falls SD

9 min drive from Denny Sanford Premier Center

Stay in the lap of luxury at Econo Lodge Sioux Falls Empire Mall, where you can enjoy amenities like premium channels, flat-screen TVs, and more.

7/10 Good! (442 reviews)

Economy hotel, no thrills, but it's nice

"Staff was really nice. Rooms are spacious. Good value and convenient to many stores/restaurants, etc. Rooms for clean."

Reviewed on 2022/10/18

My Place Hotel - Sioux Falls, SD

3005 S. Carolyn Ave Sioux Falls SD

8 min drive from Denny Sanford Premier Center

Go for a luxurious stay at My Place Hotel - Sioux Falls, SD, where you can enjoy amenities like pillowtop beds, premium channels, and more.

8.4/10 Very Good! (1,017 reviews)

"It’s great that you have all the stuff in the room, stove, fridge, sink; but come on; how many people travel with all its you would need to use them. A waste that we are paying for. The guy at check in seemed more annoyed at having to come out and do his job. Definitely will stay elsewhere when traveling ..."

Reviewed on 2026/8/24

See all 979 properties in Eastern South Dakota

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.