Photo by Martin Tucker

Plan, book, travel with confidence
Better together
Save up to NT$25,000 when you book a flight and hotel together*
Find the right fit
With over 300,000 hotels worldwide, it's easy to create a perfect package
Rest easy
Plan, book, and manage your trip all in one place

Top Luxury Northeast Mississippi Hotels

Super 8 by Wyndham Oxford

2201 Jackson Ave W Oxford MS

5 min drive from University of Mississippi

Treat yourself to some sumptuous lodging at Super 8 by Wyndham Oxford, where you'll find deep soaking bathtubs and premium bedding. The outdoor pool and hot ...

5.8/10 (1,014 reviews)

Nothing fresh for breakfast. All cold food. No room service the 3 days I stayed there. TV is terrible. Had no idea how to select a channel. No guide in the room.

Reviewed on 2026/5/13

Spark by Hilton Tupelo

186 Stone Creek Blvd Tupelo MS

2 hours drive from University of Mississippi

Indulge in a luxury vacation at Spark by Hilton Tupelo.

8.4/10 Very Good! (1,000 reviews)

Span call to room saying the computers went down and needed credit card information. Clerk did not know how they could have called rooms. there were at least two different rooms called. Did not give information and went downstairs.

Reviewed on 2026/5/11

Quality Inn Tupelo Central

1190 N Gloster St Tupelo MS

2 hours drive from University of Mississippi

Choose luxury at Quality Inn Tupelo Central, where you can enjoy amenities like plush bedding, premium channels, and more. Deluxe amenities at this hotel include ...

7.8/10 Good! (563 reviews)

Horrible condition building. Room smelled horrible. Walked in room and walked right back out. Woman at front desk was amazing, only good part of experience

Reviewed on 2026/5/12

See all 1,420 properties in Northeast Mississippi

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.