Photo by RVLuckyorWhat

Plan, book, travel with confidence
Better together
Save up to NT$25,000 when you book a flight and hotel together*
Find the right fit
With over 300,000 hotels worldwide, it's easy to create a perfect package
Rest easy
Plan, book, and manage your trip all in one place

Top Beach Upstate South Carolina Hotels

Quality Inn Clinton - Laurens I-26

105 Trade St Clinton SC

3 hours drive from Clemson University

Book a stay at this business-friendly hotel in Clinton. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. ...

7.4/10 Good! (554 reviews)

"To be clear, the STAFF at this property were extremely kind. The room itself, especially the tub, was totally disgusting. I didn’t look at the tub when I checked in, I noticed it the next morning when I took a shower. The staff told me they were required to have bath mats and there was a delay in ..."

Reviewed on 2026/6/2

Hampton Inn & Suites Spartanburg-I-26-Westgate Mall

801 Spartan Blvd Spartanburg SC

2 hours drive from Clemson University

Stay at this hotel in Spartanburg. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. Popular attractions ...

8.6/10 Excellent! (1,000 reviews)

"Convenient location near I85 & I26"

Reviewed on 2026/5/31

Comfort Suites At WestGate Mall

458 West Blackstock Road Spartanburg SC

2 hours drive from Clemson University

Book a stay at this business-friendly hotel in Spartanburg. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful ...

8.2/10 Very Good! (1,014 reviews)

"Easy, convenient off highway to a clean, large, quiet room. Nice breakfast. Lots near by. Will stay again."

Reviewed on 2026/6/6

See all 3,011 properties in Upstate South Carolina

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.