Photo by Southernmost Illinois Tourism Bureau

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Top Adventure Southern Illinois Hotels

Best Western Heartland Inn

1416 Broadway Avenue East Mattoon IL

5 hours drive from Shawnee National Forest

Book a stay at this business-friendly hotel in Mattoon. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. ...

8.2/10 Very Good! (600 reviews)

"NIGHTMARE STAY! Several flying bugs throughout room. Bathroom was infested with what looked like roaches or some sort of beetles crawling inside the tub, sink and all over the floor & walls. Took pics and video to show General Manager, Celeste. After having to make several calls over a 2 week period ..."

Reviewed on 2026/6/24

SureStay Hotel by Best Western Whittington Rend Lake

13277 Freeway Lane Whittington IL

2 hours drive from Shawnee National Forest

Book a stay at this business-friendly hotel in Whittington. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...

8.8/10 Excellent! (985 reviews)

"Great place for an overnight stay!! Clean, comfy beds and cold AC!"

Reviewed on 2026/6/26

Hampton Inn Carbondale

2175 Reed Station Pkwy Carbondale IL

2 hours drive from Shawnee National Forest

Book a stay at this business-friendly hotel in Carbondale. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...

8.4/10 Very Good! (651 reviews)

"Hotel needs repair but room was good, clean and quiet. Some of the light bulbs in room needed replacing. Location was great for what we needed. Breakfast was adequate and clean."

Reviewed on 2026/6/25

See all 1,136 properties in Southern Illinois

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.