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Top Adventure Central United States Hotels

Moody Gardens Hotel, Spa and Convention Center

7 Hope Blvd Galveston TX

24 hours drive from Great Smoky Mountains National Park

Book a stay at this spa resort in Galveston. Enjoy free WiFi, free parking, and a full-service spa. Our guests praise the pool and the helpful staff in our reviews. ...

Cooper Hotel Conference Center & Spa

12230 Preston Road Dallas TX

4 hours drive from Great Smoky Mountains National Park

Book a stay at this spa hotel in Dallas. Enjoy free WiFi, free parking, and 2 outdoor pools. Our guests praise the helpful staff and the clean rooms in our reviews. ...

Margaritaville Resort Biloxi

195 Beach Blvd Biloxi MS

13 hours drive from Great Smoky Mountains National Park

Book a stay at this beach hotel in Biloxi. Enjoy free WiFi, an outdoor pool, and 3 restaurants. Our guests praise the pool and the helpful staff in our reviews. ...

8.6/10 Excellent! (6,494 reviews)

"Amazing place to stay will stay again looking to book for next year as we speak"

Reviewed on 2026/11/2

See all 322,181 properties in Central United States

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.