Southern Minnesota Adventure Vacations 2026

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Top Adventure Southern Minnesota Hotels

Kahler Grand Hotel

20 2nd Ave Sw Rochester MN

2 min walk from Mayo Clinic

Book a stay at this business-friendly hotel in Rochester. Enjoy free WiFi, 2 restaurants, and breakfast (surcharge). Our guests praise the helpful staff and ...

8.4/10 Very Good! (2,337 reviews)

"Unable to access account information on TV, so had to go to lobby to check out. Very nice restaurant."

Reviewed on 2026/10/1

Willow Inn Suites Rochester

4323 Highway 52 North, West Frontage Rd Rochester MN

10 min drive from Mayo Clinic

Book a stay at this business-friendly hotel in Rochester. Enjoy free WiFi, free parking, and a 24-hour front desk. Our guests praise the helpful staff in our ...

AmericInn by Wyndham Mankato Event Center

240 Stadium Road Mankato MN

4 hours drive from Mayo Clinic

Book a stay at this business-friendly hotel in Mankato. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...

9.4/10 Exceptional! (1,001 reviews)

"Clean and with good amenities"

Reviewed on 2026/9/30

See all 1,232 properties in Southern Minnesota

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.