
Central United States Pet-friendly Vacations
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Top Pet-friendly Central United States Hotels

Drury Inn & Suites Amarillo
8540 W Interstate 40 Amarillo TX
- 31 hours drive from Great Smoky Mountains National Park
This pet-friendly hotel welcomes dogs and cats (fees apply).
9.4/10 Exceptional! (2,464 reviews)
"I would say that everything was excellent except for the Breakfast. Tried the eggs and biscuit and gravy. Did not finish them. Did not taste quite right. Raisin bread and muffins were great."
Reviewed on 2026/9/15

La Quinta Inn & Suites by Wyndham Chattanooga - East Ridge
6650 Ringgold Rd Chattanooga TN
- 4 hours drive from Great Smoky Mountains National Park
This pet-friendly hotel welcomes dogs and cats (fees apply).
8.8/10 Excellent! (1,001 reviews)
"everything as expected... loved the breakfast"
Reviewed on 2026/9/15

La Quinta Inn & Suites by Wyndham Chattanooga - Lookout Mtn
311 Browns Ferry Rd Chattanooga TN
- 4 hours drive from Great Smoky Mountains National Park
Dogs and cats may join you (for a fee) during your stay at this pet-friendly hotel. Take the opportunity to stretch your legs on the nearby hiking or biking ...
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.
