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Top Pet-friendly Upstate South Carolina Hotels

Aloft Greenville Downtown

5 North Laurens Street Greenville SC

1 hour drive from Clemson University

Dogs and cats are welcome (fees apply) at this city-center hotel offering pet-friendly amenities, like food and water bowls. While you're here, take a stroll ...

9/10 Wonderful! (1,005 reviews)

Everything was great except for the mattress in the room. The mattresses need to be replaced. You can feel the springs and there was a hole that I kept rolling into. In addition, the shower needs more pressure.

Reviewed on 2026/1/19

La Quinta Inn & Suites by Wyndham Greenville Haywood

65 W Orchard Park Dr Greenville SC

1 hour drive from Clemson University

This hotel is pet-friendly, allowing dogs and cats with an additional fee. If you're going for a walk during your stay, swing by nearby Butler Springs Park.

7.2/10 Good! (1,134 reviews)

Yes

Reviewed on 2026/1/16

Best Western Greenville Airport Inn

5009 Pelham Road Greenville SC

2 hours drive from Clemson University

Dogs and cats will approve of the pet-friendly amenities, such as a dog park, during their stay at this hotel (fees apply for pets).

7.6/10 Good! (1,000 reviews)

It was clean nice peaceful and quiet no disturbance rest well great

Reviewed on 2025/12/24

See all 2,911 properties in Upstate South Carolina

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.