Central United States Luxury Vacations 2026

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Top Luxury Central United States Hotels

The Peabody Memphis

149 Union Avenue Memphis TN

11 hours drive from Great Smoky Mountains National Park

Be treated to luxurious accommodations at The Peabody Memphis, where you can enjoy amenities like 24-hour room service, pillowtop beds, and more. The 2 bars, ...

9.4/10 Exceptional! (1,012 reviews)

"Beautiful property. Excellent staff."

Reviewed on 2026/10/10

The St. Anthony, A Luxury Collection Hotel, San Antonio

300 E Travis St San Antonio TX

25 hours drive from Great Smoky Mountains National Park

Be treated to luxurious accommodations at The St. Anthony, A Luxury Collection Hotel, San Antonio, where you can enjoy amenities like pillowtop beds, designer ...

Hotel Viata

320 S. Capital of Texas Hwy, Bldg. B Austin TX

Go for a luxurious stay at Hotel Viata, where you can enjoy amenities like Champagne service, plush bedding, and more. Deluxe amenities at this hotel include ...

See all 318,202 properties in Central United States

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.