San Luis Obispo Wine Country Luxury Vacations

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Top Luxury San Luis Obispo Wine Country Hotels

Madonna Inn

Madonna Inn

3.5 out of 5
100 Madonna Road, San Luis Obispo, CA
  • 6 min drive from California Polytechnic State University
Madonna Inn delivers luxe lodging where you'll enjoy pillowtop beds and more. Notable amenities include a spa, 2 outdoor tennis courts, and an outdoor pool.
Madonna Inn
Avenue Inn Downtown San Luis Obispo

Avenue Inn Downtown San Luis Obispo

2.5 out of 5
345 Marsh St, San Luis Obispo, CA
  • 4 min drive from California Polytechnic State University
Be treated to luxurious accommodations at Avenue Inn Downtown San Luis Obispo, where you can enjoy amenities like premium channels, flat-screen TVs, and ...
Avenue Inn Downtown San Luis Obispo
Avila La Fonda Hotel

Avila La Fonda Hotel

4 out of 5
101 San Miguel St, Avila Beach, CA
  • 22 min drive from California Polytechnic State University
Enjoy a posh stay at Avila La Fonda Hotel, where you'll find private hot tubs and pillowtop beds.
Avila La Fonda Hotel
See all 1,844 properties in San Luis Obispo Wine Country
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.