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Top Adventure Southeast Jacksonville Hotels

Delta Hotels by Marriott™ Jacksonville Deerwood

4700 Salisbury Rd Jacksonville FL

10 min drive from Mayo Clinic Florida

Book a stay at this business-friendly hotel in Jacksonville. Enjoy breakfast (surcharge), a free area shuttle, and room service. Our guests praise the helpful ...

8.4/10 Very Good! (645 reviews)

"Delta Pantry access was great!"

Reviewed on 2026/6/9

Residence Inn by Marriott Jacksonville Butler Boulevard

10551 Deerwood Park Blvd Jacksonville FL

7 min drive from Mayo Clinic Florida

Book a stay at this business-friendly hotel in Jacksonville. Enjoy free breakfast, free WiFi, and a fitness center. Our guests praise the helpful staff and the ...

8.6/10 Excellent! (1,002 reviews)

"Very clean, staff very professional only thing we wanted better looking sheets and they gave us better sheets and everything else was good"

Reviewed on 2026/6/7

Marriott Jacksonville

4670 Salisbury Rd Jacksonville FL

10 min drive from Mayo Clinic Florida

Book a stay at this business-friendly hotel in Jacksonville. Enjoy free parking, breakfast (surcharge), and room service. Our guests praise the helpful staff ...

8.8/10 Excellent! (991 reviews)

"The Bar was the best service 💕💕"

Reviewed on 2026/6/5

See all 586 properties in Southeast Jacksonville

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.