Cheap flights from Columbus to Knoxville (CMH to TYS)

A tower with a spherical top, fireworks in the sky, and a cityscape with buildings and a tented area.

Popular airlines from John Glenn Columbus Intl. Airport (CMH) to McGhee Tyson Airport (TYS)

Be in the know
Get alerts if flight prices drop or rise*
Book smarter
Save up to 45% on select hotels after you book a flight*
Earn twice
Earn your airline miles on top of our rewards
Sign in

Travel information

Origin airport	John Glenn Columbus Intl. Airport
Destination airport	McGhee Tyson Airport
Distance	476 km away
Airlines serving	American Airlines, Southwest Airlines, Delta, United
Popular airline	American Airlines

Explore a world of travel with Expedia

Flights from Lakeland Intl. Airport (LAL) to Knoxville (TYS)
Standard Link for Flights from Lakeland Intl. Airport (LAL) to Knoxville (TYS)
Flights from Anchorage (MRI) to Knoxville (TYS)
Standard Link for Flights from Anchorage (MRI) to Knoxville (TYS)
Flights from San Antonio (SAT) to Knoxville (TYS)
Standard Link for Flights from San Antonio (SAT) to Knoxville (TYS)
Flights from Harlingen (HRL) to Knoxville (TYS)
Standard Link for Flights from Harlingen (HRL) to Knoxville (TYS)
Flights from Tirana (TIA) to Knoxville (TYS)
Standard Link for Flights from Tirana (TIA) to Knoxville (TYS)
Flights from San Bernardino (SBD) to Knoxville (TYS)
Standard Link for Flights from San Bernardino (SBD) to Knoxville (TYS)
Flights from Somerset (SME) to Knoxville (TYS)
Standard Link for Flights from Somerset (SME) to Knoxville (TYS)
Flights from Kokomo (OKK) to Knoxville (TYS)
Standard Link for Flights from Kokomo (OKK) to Knoxville (TYS)
Flights from Show Low (SOW) to Knoxville (TYS)
Standard Link for Flights from Show Low (SOW) to Knoxville (TYS)
Flights from Clemson (CEU) to Knoxville (TYS)
Standard Link for Flights from Clemson (CEU) to Knoxville (TYS)
Flights from Los Angeles (LAX) to Knoxville (TYS)
Standard Link for Flights from Los Angeles (LAX) to Knoxville (TYS)
Flights from Punta Arenas (PUQ) to Knoxville (TYS)
Standard Link for Flights from Punta Arenas (PUQ) to Knoxville (TYS)
Flights from Aberdeen (ABZ) to Knoxville (TYS)
Standard Link for Flights from Aberdeen (ABZ) to Knoxville (TYS)
Flights from Granada (GRX) to Knoxville (TYS)
Standard Link for Flights from Granada (GRX) to Knoxville (TYS)
Flights from Walland
Standard Link for Flights from Walland
Flights from Samos (SMI) to Knoxville (TYS)
Standard Link for Flights from Samos (SMI) to Knoxville (TYS)
Flights from Kenora (YQK) to Knoxville (TYS)
Standard Link for Flights from Kenora (YQK) to Knoxville (TYS)
Flights from Schenectady (SCH) to Knoxville (TYS)
Standard Link for Flights from Schenectady (SCH) to Knoxville (TYS)
Flights from Stella Maris (SML) to Knoxville (TYS)
Standard Link for Flights from Stella Maris (SML) to Knoxville (TYS)
Flights from Astoria (AST) to Knoxville (TYS)
Standard Link for Flights from Astoria (AST) to Knoxville (TYS)
Flights from Longyearbyen (LYR) to Knoxville (TYS)
Standard Link for Flights from Longyearbyen (LYR) to Knoxville (TYS)
Flights from Gainesville (GVL) to Knoxville (TYS)
Standard Link for Flights from Gainesville (GVL) to Knoxville (TYS)
Flights from Isafjordur (IFJ) to Knoxville (TYS)
Standard Link for Flights from Isafjordur (IFJ) to Knoxville (TYS)
Flights from Auburn (AUO) to Knoxville (TYS)
Standard Link for Flights from Auburn (AUO) to Knoxville (TYS)
Flights from New York (NYC) to Knoxville (TYS)
Standard Link for Flights from New York (NYC) to Knoxville (TYS)
Flights from Tifton (TMA) to Knoxville (TYS)
Standard Link for Flights from Tifton (TMA) to Knoxville (TYS)
Flights from Brasilia (BSB) to Knoxville (TYS)
Standard Link for Flights from Brasilia (BSB) to Knoxville (TYS)
Flights from Bird Island (BDI) to Knoxville (TYS)
Standard Link for Flights from Bird Island (BDI) to Knoxville (TYS)
Flights from Iwakuni (IWK) to Knoxville (TYS)
Standard Link for Flights from Iwakuni (IWK) to Knoxville (TYS)
Flights from Seattle (SEA) to Knoxville (TYS)
Standard Link for Flights from Seattle (SEA) to Knoxville (TYS)
Flights to Knoxville
Standard Link for Flights to Knoxville
Flights from Whitehorse (YXY) to Knoxville (TYS)
Standard Link for Flights from Whitehorse (YXY) to Knoxville (TYS)

*Available to One Key members.

Cheap Flights from Columbus (CMH) to Knoxville (TYS)

Popular airlines from John Glenn Columbus Intl. Airport (CMH) to McGhee Tyson Airport (TYS)

Be in the know

Book smarter

Earn twice

Travel information

Explore a world of travel with Expedia