
Uptown - Upper Duval Vacations
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Where to stay in Uptown - Upper Duval
Find the best Uptown - Upper Duval areas and neighborhoods for the activities you enjoy most. Learn more about Uptown - Upper Duval

Old Town Key West
3 out of top 10 points of interest in this area
4.5/5(226 area reviews)
Old Town, the historic heart of Key West, boasts a central business district and numerous tourist attractions. Explore the Key West Aquarium, Ernest Hemingway House, Mallory Square, and more in this vibrant area.
Uptown - Upper Duval Hotel Deals

Southernmost Beach Resort and Guesthouses
1319 Duval Street, Key West, FL
Fully refundable
The price is NT$5,172 per night from Oct 29 to Oct 30
NT$5,172
NT$7,879 total
Oct 29 - Oct 30
includes taxes & fees
8.6/10 Excellent! (2,771 reviews)
"Good location"
Reviewed on 2025/9/23

The Reach Key West, Curio Collection by Hilton
1435 Simonton Street, Key West, FL
Fully refundableReserve now, pay when you stay
The price is NT$6,214 per night from Oct 5 to Oct 6
NT$6,214
NT$8,822 total
Oct 5 - Oct 6
includes taxes & fees
8.4/10 Very Good! (1,013 reviews)
"Great staff, view and food!"
Reviewed on 2025/9/24

Southwinds Motel
1321 Simonton Street, Key West, FL
The price is NT$3,819 per night from Sep 29 to Sep 30
NT$3,819
NT$5,155 total
Sep 29 - Sep 30
includes taxes & fees
8.6/10 Excellent! (1,185 reviews)
"The room was nice, & the area was fairly good. Near the Southernmost Point marker. Only downside was the water pressure was pretty weak."
Reviewed on 2025/9/22
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Frequently asked questions
Discover the most popular places to visit in Uptown - Upper Duval

Southernmost Point
Snap a memorable photograph from the edge of North America at this monumental landmark.

South Beach
The southernmost beach in the continental United States is a convenient sandy enclave, just minutes from the center of town.

Key West Butterfly and Nature Conservatory
With about 60 species of butterfly, an indoor waterfall and a tropical rainforest, this nature conservatory is one of the most popular attractions in Key West.
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.